From Traditional Nanoparticles to Cluster-Triggered Emission Polymers for the Generation of Smart Nanotheranostics in Cancer Treatment
Journal of Nanotheranostics,
Год журнала:
2025,
Номер
6(1), С. 3 - 3
Опубликована: Янв. 22, 2025
Nanotheranostics
integrates
diagnostic
and
therapeutic
functionalities
using
nanoscale
materials,
advancing
personalized
medicine
by
enhancing
treatment
precision
reducing
adverse
effects.
Key
materials
for
nanotheranostics
include
metallic
nanoparticles,
quantum
dots,
carbon
lipid
nanoparticles
polymer-based
nanocarriers,
each
offering
unique
benefits
alongside
specific
challenges.
Polymer-based
including
hybrid
superparamagnetic
improve
stability
functionality
but
are
complex
to
manufacture.
Polymeric
with
aggregation-induced
emission
(AIE)
present
promising
theranostic
potential
cancer
detection
treatment.
However,
challenges
such
as
translating
the
AIE
concept
living
systems,
addressing
toxicity
concerns,
overcoming
deep-tissue
imaging
limitations,
or
ensuring
biocompatibility
remain
be
resolved.
Recently,
cluster-triggered
(CTE)
polymers
have
emerged
innovative
in
nanotheranostics,
enhanced
fluorescence
biocompatibility.
These
exhibit
increased
intensity
upon
aggregation,
making
them
highly
sensitive
applications.
CTE
crafted
from
biodegradable
polymers,
represent
a
safer
alternative
traditional
that
rely
on
embedding
conventional
fluorophores
metal-based
agents.
This
advancement
significantly
reduces
while
The
intrinsic
allows
real-time
monitoring
of
drug
distribution
activity,
optimizing
efficacy.
Despite
their
potential,
these
systems
face
maintaining
under
physiological
conditions
need
comprehensive
safety
efficacy
studies
meet
clinical
regulatory
standards.
Nevertheless,
properties
position
candidates
strategies
medicine,
bridging
ways.
Язык: Английский
Advances in phototheranostic agents: From imaging to targeted therapy
Materials Today Chemistry,
Год журнала:
2025,
Номер
43, С. 102516 - 102516
Опубликована: Янв. 1, 2025
Язык: Английский
Bio-inspired nitrogen-doped carbon quantum dots: A green route for bioimaging and nano-biosensing
Industrial Crops and Products,
Год журнала:
2025,
Номер
227, С. 120817 - 120817
Опубликована: Март 14, 2025
Язык: Английский
Converting waste Chrysanthemi Flos residues into high-value fluorescent carbon dots for rapid and selective detection of mercury (II) ions in aqueous environments
Industrial Crops and Products,
Год журнала:
2025,
Номер
228, С. 120914 - 120914
Опубликована: Март 31, 2025
Язык: Английский
Kinetic analysis and modelling of therapeutically important dodeca-2E,4E,8Z,10E, Z-tetraenoic acid isobutylamides production from adventitious root cultures of Spilanthes paniculata Wall. ex DC.
Industrial Crops and Products,
Год журнала:
2025,
Номер
229, С. 120997 - 120997
Опубликована: Апрель 11, 2025
Язык: Английский