Naturally sourced hydrogels: emerging fundamental materials for next-generation healthcare sensing

Chemical Society Reviews, Год журнала: 2023, Номер 52(9), С. 2992 - 3034

Опубликована: Янв. 1, 2023

The flourishing development of flexible healthcare sensing systems is inseparable from the fundamental materials with application-oriented mechanical and electrical properties. Thanks to continuous inspiration our Mother Nature, hydrogels originating natural biomass are attracting growing attention for their structural functional designs owing unique chemical, physical biological These highly efficient architectural enable them be most promising candidates electronic devices. This comprehensive review focuses on recent advances in naturally sourced constructing multi-functional sensors applications thereof. We first briefly introduce representative polymers, including polysaccharides, proteins, polypeptides, summarize physicochemical design principles fabrication strategies hydrogel based these polymers outlined after material properties required presented. then highlight various techniques devices, illustrate examples wearable or implantable bioelectronics pressure, strain, temperature, biomarker field systems. Finally, concluding remarks challenges prospects hydrogel-based provided. hope that this will provide valuable information next-generation build a bridge between as matter an applied target accelerate new near future.

Язык: Английский

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Strong and Tough Physical Eutectogels Regulated by the Spatiotemporal Expression of Non‐Covalent Interactions

Advanced Functional Materials, Год журнала: 2022, Номер 32(41)

Опубликована: Авг. 5, 2022

Abstract Physical eutectogels are appealing materials for technological devices due to their superior ionic conductivity, thermal and electrochemical stability, non‐volatility, low cost. Nevertheless, current physical suffering from weak mechanical strength toughness. Here, taking advantage of the distribution difference polyvinyl alcohol (PVA) in water deep eutectic solvents (DESs), a simple universal solvent‐replacement approach is proposed regulate spatiotemporal expression intra/interpolymer interactions prepare strong tough eutectogels. The exchange DESs with can restrengthen weakened between PVA chains water, enabling crystallize construct uniform robust polymer network. Consequently, resultant eutectogel exhibits record‐high (20.2 MPa), toughness (62.7 MJ m –3 ), tear‐resistance (tearing energy Σ42.4 kJ –2 while possessing excellent stretchability (Σ550% strain), repairability, adhesive performance. Furthermore, this strategy proven be universally applicable various species polymers, even utilized fabricate continuous conductive fibers, demonstrating potential as engineering wearable sensors.

Язык: Английский

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Water‐Resistant Ionogel Electrode with Tailorable Mechanical Properties for Aquatic Ambulatory Physiological Signal Monitoring

Advanced Functional Materials, Год журнала: 2021, Номер 31(51)

Опубликована: Сен. 19, 2021

Abstract Underwater electrocardiography (ECG) monitoring, which can monitor cardiac autonomic changes and arrhythmias during diving, is essential for sports management healthcare. However, it crucial yet rather challenging to achieve ECG monitoring in an aquatic environment because the interface electrodes may lose their functionality underwater. Here, ionogel with tailorable mechanical properties prepared by a facile one‐step polymerization used as water‐resistant electrode. The Young's modulus strain at break of be modulated range 0.22–337 MPa 349 >10 000%, respectively. hydrophobic polymer networks inside endow this excellent stability, adhesion, self‐healing ability ionic conductivity imparted free groups allows detect transmit physiological electrical signals. Compared commercial gel electrodes, electrode demonstrates better adhesion ability, conductivity, stability collect real‐time signals effectively both air underwater, data warn users potential risk heart attack.

Язык: Английский

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Highly Stretchable Hydrogels as Wearable and Implantable Sensors for Recording Physiological and Brain Neural Signals

Advanced Science, Год журнала: 2022, Номер 9(16)

Опубликована: Март 31, 2022

Recording electrophysiological information such as brain neural signals is of great importance in health monitoring and disease diagnosis. However, foreign body response performance loss over time are major challenges stemming from the chemomechanical mismatch between sensors tissues. Herein, microgels utilized large crosslinking centers hydrogel networks to modulate tradeoff modulus fatigue resistance/stretchability for producing hydrogels that closely match properties The exhibit notably different characteristics compared nanoparticles reinforced hydrogels. relatively low modulus, good stretchability, outstanding resistance. It demonstrated well suited fashioning into wearable implantable can obtain physiological pressure signals, record local field potentials rat brains, transmit through injured peripheral nerves rats. tissues, negligible response, minimal signal attenuation an extended time, successfully use long-term sensory devices. This work facilitates a deeper understanding biohybrid interfaces, while also advancing technical design concepts probes efficiently information.

Язык: Английский

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Tough and Ultrastretchable Liquid‐Free Ion Conductor Strengthened by Deep Eutectic Solvent Hydrolyzed Cellulose Microfibers

Advanced Functional Materials, Год журнала: 2022, Номер 32(29)

Опубликована: Май 3, 2022

Abstract Ion conductors (ICs) have gained extensive research interest in various advanced application scenarios including sensors, batteries, and supercapacitors. However, stretchable, tough, long‐term stable ICs are still hard to achieve yet highly demanded. In this study, the authors propose a one‐pot green sustainable fabrication of cellulose based through polymerizable deep eutectic solvents treated followed by an situ photo‐polymerization. The obtained exhibit extremely high stretchability (3210 ± 302%), toughness (13.17 2.32 MJ m −3 ), transparency, self‐healing ability. Notably, introduction fibers greatly enhances mechanical properties while eliminating environmental concerns traditional nanocellulose process. More importantly, possess good performance stability after 1 month storage. Due these outstanding properties, feasibility applying human motion sensing physiological signal detecting is demonstrated. This simple method will contribute development self‐healing, transparent, ICs.

Язык: Английский

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Highly stretchable, self-healing, and adhesive polymeric eutectogel enabled by hydrogen-bond networks for wearable strain sensor

Chemical Engineering Journal, Год журнала: 2022, Номер 449, С. 137878 - 137878

Опубликована: Июль 2, 2022

Язык: Английский

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Mechanically Robust and Highly Conductive Ionogels for Soft Ionotronics

Advanced Functional Materials, Год журнала: 2022, Номер 33(10)

Опубликована: Дек. 25, 2022

Abstract Ionogels are promising materials for flexible electronics due to their continuous conductive phase, high thermal and chemical stability. However, a large amount of ionic liquid is required get conductivity, resulting in sharp decline the mechanical properties. Therefore, it great challenge prepare ionogels with both conductivity properties, which important practical applications. Herein, strength stretchability, extraordinary excellent transparency, outstanding durability, stability fabricated crosslinked polymer, liquid, lithium salt. The adoption salt can significantly improve common dilemma material science, simultaneously, address conflict between ionogels. It primarily corresponding microphase‐separation effects induced by bonds formed ions carbonyl groups on polymer networks. Ionotronics including resistance‐type sensors strain temperature sensing triboelectric nanogenerators stable output performance fabricated. Moreover, ionogel‐based microcircuit arrays resolution accuracy through digital light processing printing technology. have promise various ionotronics many fields.

Язык: Английский

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Highly conductive, stretchable, durable, breathable electrodes based on electrospun polyurethane mats superficially decorated with carbon nanotubes for multifunctional wearable electronics

Chemical Engineering Journal, Год журнала: 2022, Номер 451, С. 138549 - 138549

Опубликована: Авг. 9, 2022

Язык: Английский

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NIR light-induced rapid self-healing hydrogel toward multifunctional applications in sensing

Nano Energy, Год журнала: 2022, Номер 107, С. 108119 - 108119

Опубликована: Дек. 26, 2022

Язык: Английский

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In Situ Forming Dual‐Conductive Hydrogels Enable Conformal, Self‐Adhesive and Antibacterial Epidermal Electrodes

Advanced Functional Materials, Год журнала: 2023, Номер 33(38)

Опубликована: Май 26, 2023

Abstract Conductive hydrogels (CHs) are regarded as one of the most promising materials for bioelectronic devices on human‐machine interfaces (HMIs). However, conventional CHs cannot conform well with complex skin surfaces, such hairy or wrinkled skin, due to pre‐formation and insufficient adhesion; they also usually lack antibacterial abilities require tissue‐harm time‐consuming preparation (e.g., heating ultraviolet irradiation), which limits their practical application HMIs. Herein, an in situ forming CH is proposed by taking advantage PEDOT:PSS‐promoted self‐polymerization zwitterionic [2‐(methacryloyloxy)ethyl]dimethyl‐(3‐sulfopropyl) (SBMA). The hydrogel formed spontaneously after injection precursor solution onto desired location without any additional treatments. as‐prepared possesses excellent elasticity (elastic recovery >96%), desirable adhesive strength (≈6.5 kPa), biocompatibility, intrinsically properties. Without apparent heat release (<5 °C) during gelation, can form skin. Additionally, obtained establish tight contact highly conformal surfaces irregular wounds. Finally, applied epidermal electrodes record stable reliable surface electromyogram signals from (with high signal‐to‐noise ratio, SNR ≈ 32 dB) accelerate diabetic wound healing under electrical stimulation.

Язык: Английский

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