Vascular
diseases
(VDs)
pose
the
leading
threat
worldwide
due
to
high
morbidity
and
mortality.
The
detection
of
VDs
is
commonly
dependent
on
individual
signs,
which
limits
accuracy
timeliness
therapies,
especially
for
asymptomatic
patients
in
clinical
management.
Therefore,
more
effective
early
diagnosis
lesion-targeted
treatments
remain
a
pressing
need.
Metal-organic
frameworks
(MOFs)
are
porous
crystalline
materials
formed
by
coordination
inorganic
metal
ions
organic
ligands.
Due
their
unique
specific
surface
area,
structural
flexibility,
functional
versatility,
MOFs
recognized
as
highly
promising
candidates
diagnostic
therapeutic
applications
field
VDs.
In
this
review,
potential
act
biosensors,
contrast
agents,
artificial
nanozymes,
multifunctional
agents
treatment
from
perspective,
highlighting
integration
between
methods
with
generalized.
At
same
time,
multidisciplinary
cooperation
chemistry,
physics,
biology,
medicine
promote
substantial
commercial
transformation
tackling
called
for.
Journal of Materials Chemistry B,
Год журнала:
2023,
Номер
11(27), С. 6172 - 6200
Опубликована: Янв. 1, 2023
Porphyrins
are
naturally
occurring
organic
molecules
that
have
attracted
widespread
attention
for
their
potential
in
the
field
of
biomedical
research.
Porphyrin-based
metal-organic
frameworks
(MOFs)
utilize
porphyrin
as
ligands
gained
from
researchers
due
to
excellent
results
photosensitizers
tumor
photodynamic
therapy
(PDT).
Additionally,
MOFs
hold
significant
promise
and
other
therapeutic
approaches
tunable
size
pore
size,
porosity,
ultra-high
specific
surface
area.
Active
delivery
nanomaterials
via
targeted
has
demonstrated
greater
accumulation,
lower
drug
doses,
higher
efficacy,
reduced
side
effects
relative
passive
targeting
through
enhanced
permeation
retention
effect
(EPR).
This
paper
presents
a
comprehensive
review
methods
employed
by
porphyrin-based
over
past
few
years.
It
further
discusses
applications
cancer
various
methods.
The
objective
this
is
provide
valuable
reference
source
ideas
using
MOF
materials
inspire
exploration
therapy.
Ecotoxicology and Environmental Safety,
Год журнала:
2023,
Номер
269, С. 115854 - 115854
Опубликована: Дек. 27, 2023
Chlorination
is
a
versatile
technique
to
combat
water-borne
pathogens.
Over
the
last
years,
there
has
been
continued
research
interest
abate
formation
of
chlorinated
disinfection
by-products
(DBPs).
To
prevent
hazardous
DBPs
in
drinking
water,
it
decided
diminish
organic
precursors,
among
which
humic
acids
(HA)
resulting
from
decomposition
and
transformation
biomass.
Metal-organic
frameworks
(MOFs)
such
as
zeolitic
imidazolate
(ZIFs)
have
recently
received
tremendous
attention
water
purification.
Herein,
customized
ZIF-67
MOFs
possessing
various
physicochemical
properties
were
prepared
by
changing
cobalt
source.
The
HA
removal
ZIF-67-Cl,
ZIF-67-OAc,
ZIF-67-NO
Vascular
diseases
(VDs)
pose
the
leading
threat
worldwide
due
to
high
morbidity
and
mortality.
The
detection
of
VDs
is
commonly
dependent
on
individual
signs,
which
limits
accuracy
timeliness
therapies,
especially
for
asymptomatic
patients
in
clinical
management.
Therefore,
more
effective
early
diagnosis
lesion-targeted
treatments
remain
a
pressing
need.
Metal-organic
frameworks
(MOFs)
are
porous
crystalline
materials
formed
by
coordination
inorganic
metal
ions
organic
ligands.
Due
their
unique
specific
surface
area,
structural
flexibility,
functional
versatility,
MOFs
recognized
as
highly
promising
candidates
diagnostic
therapeutic
applications
field
VDs.
In
this
review,
potential
act
biosensors,
contrast
agents,
artificial
nanozymes,
multifunctional
agents
treatment
from
perspective,
highlighting
integration
between
methods
with
generalized.
At
same
time,
multidisciplinary
cooperation
chemistry,
physics,
biology,
medicine
promote
substantial
commercial
transformation
tackling
called
for.
