3d-Printed Advanced Multifunctional 58s Bg/Ag/Ceo2-Based Composite Scaffolds For Bone Tissue Engineering DOI
Indrajeet Singh, Ing Kong,

Ashok Viswakarma

и другие.

Опубликована: Янв. 1, 2024

58S Bioglass (BG) has been considered an effective bioceramics in bone tissue engineering for accelerating healing, however, its poor antibacterial and printing properties remain a challenge developing ideal patient-specific fully interconnected bone-like scaffolds. Therefore, this study, novel 3D printed BG/Ag/CeO2-(BGAC3D) based composites scaffold with pores (≈99%) porosity of ≈64% highly suitable pore strut sizes 404 ±15 µm, 394 ±30 µm healing have developed. Adding AgNPs, nanoceria significantly increased the by bridging microcracks dimensional accuracy. The nanoindentation studies revealed that BGAC3D exhibited increase elastic modulus (10 mm disc), hardness compressive strength 76% (⁓57.9 ±8 GPa), 24% (⁓3.1 ±1 275% (1.5 ±0.4 MPa), respectively, concerning BG.At same time, adding silver ceria nanoparticles BG ⁓99.3, 99.4% against Escherichia coli Staphylococcus aureus, respectively. Additionally, cytocompatibility apatite mineralization were comparable to pristine BG. Thus, on results, could be scaffolding composition repairing damaged ineffective healing.

Язык: Английский

Innovative Insights into Samarium–Doped 58SiO2-(36-x)CaO-6P2O5- xSm2O3 Bioceramics: A Comprehensive Study utilizing Bioactivity, Cytotoxicity, and Photoluminescence Behaviors DOI
Mukesh Kumar,

Vikas Anand

Ceramics International, Год журнала: 2025, Номер unknown

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

1

Advanced alginate/58S bioactive glass inks with enhanced printability, mechanical strength, and cytocompatibility for soft tissue engineering DOI Creative Commons
Indrajeet Singh,

Santosh T. R. B. Rao,

Helen Irving

и другие.

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 141106 - 141106

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0

Advanced 3D-printed Antibacterial Nano 58S Bioglass/AgNPs/CeO2-based Scaffolds for Bone Tissue Engineering DOI Creative Commons
Indrajeet Singh, Ing Kong,

Ashok Viswakarma

и другие.

Ceramics International, Год журнала: 2025, Номер unknown

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0

Atomic force microscopic investigations of transient early-stage bacterial adhesion and antibacterial activity of silver and ceria modified bioactive glass DOI Creative Commons

Shivani Gour,

Abhijit Mukherjee, Kantesh Balani

и другие.

Journal of materials research/Pratt's guide to venture capital sources, Год журнала: 2024, Номер unknown

Опубликована: Июль 31, 2024

Abstract Bioactive glass 58S (BG58S) is widely recognised for its bioactivity and antibacterial properties, making it a promising material orthopaedic implant applications. This study investigates the effects of incorporating silver (BG58S-2.5Ag) cerium oxide (BG58S-5C) into BG58S on early-stage bacterial adhesion subsequent growth inhibition. Using high-intensity ball milling approach, was modified with 5% (CeO 2 ) 2.5% (Ag) nanoparticles to create homogeneous BG58S-2.5Ag BG58S-5C nanocomposites. Custom-made biomineral probes were employed measure within one second contact Gram-negative Escherichia coli Gram-positive Staphylococcus aureus , using Atomic Force Microscopy (AFM). The results demonstrated that showed significantly stronger transient bacteria compared BG58S, leading more effective long-term response. Additionally, observed effect Ag commenced contact. These findings indicate potential correlation between rate bond strengthening cell wall penetration. highlights enhancing effectiveness surfaces various biomaterial Graphical abstract

Язык: Английский

Процитировано

2

3d-Printed Advanced Multifunctional 58s Bg/Ag/Ceo2-Based Composite Scaffolds For Bone Tissue Engineering DOI
Indrajeet Singh, Ing Kong,

Ashok Viswakarma

и другие.

Опубликована: Янв. 1, 2024

58S Bioglass (BG) has been considered an effective bioceramics in bone tissue engineering for accelerating healing, however, its poor antibacterial and printing properties remain a challenge developing ideal patient-specific fully interconnected bone-like scaffolds. Therefore, this study, novel 3D printed BG/Ag/CeO2-(BGAC3D) based composites scaffold with pores (≈99%) porosity of ≈64% highly suitable pore strut sizes 404 ±15 µm, 394 ±30 µm healing have developed. Adding AgNPs, nanoceria significantly increased the by bridging microcracks dimensional accuracy. The nanoindentation studies revealed that BGAC3D exhibited increase elastic modulus (10 mm disc), hardness compressive strength 76% (⁓57.9 ±8 GPa), 24% (⁓3.1 ±1 275% (1.5 ±0.4 MPa), respectively, concerning BG.At same time, adding silver ceria nanoparticles BG ⁓99.3, 99.4% against Escherichia coli Staphylococcus aureus, respectively. Additionally, cytocompatibility apatite mineralization were comparable to pristine BG. Thus, on results, could be scaffolding composition repairing damaged ineffective healing.

Язык: Английский

Процитировано

0