The Cation−π Interaction in Chemistry and Biology

Chemical Reviews, Год журнала: 2025, Номер unknown

Опубликована: Фев. 20, 2025

The cation-π interaction is an important noncovalent binding force that impacts all areas of chemistry and biology. Extensive computational gas phase experimental studies have established the potential strength essential nature interaction. Previous reviews emphasized model systems a variety biological examples. This work includes discussion those but emphasizes other are perhaps less well appreciated. These include novel ability alkali metals in water; application to organic synthesis chemical biology; cooperative behaviors multiple interactions, including adhesive proteins from mussels similar organisms formation modulation biomolecular condensates (phase separation); interactions involved recognizing DNA/RNA.

Язык: Английский

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Rapid Fluid-Induced-Expanding Chitosan-Derived Hemostatic Sponges with Excellent Antimicrobial and Antioxidant Properties for Incompressible Hemorrhage and Wound Healing

Biomacromolecules, Год журнала: 2025, Номер 26(1), С. 689 - 704

Опубликована: Янв. 1, 2025

Chitosan-based materials are known for their excellent biocompatibility and inherent hemostatic properties. However, efficiency is significantly affected by poor wettability mechanical strength. Herein, we developed a novel super elastic sponge from mussel-inspired chitosan modified with long alkyl catechol functional groups (HMCC) via simple freezing-drying procedure. The incorporation of decanal in the HMCC enhances its antimicrobial antioxidant properties facilitates multiple interactions blood cells, thus promoting enrichment rapid hemostasis. Moreover, sponges exhibit high compressibility fluid-induced size recovery capacity, enabling wound shape adaptation to ensure minimizing irritation. In vivo experiments revealed that possessed enhanced procoagulant, hemostasis abilities, favorable degradability could promote healing rat skin model. These results highlight potential as promising solution clinical management major bleeding.

Язык: Английский

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Thioctic Acid-Based Solvent-Free and Recoverable Adhesive for Dry/Wet Environments

ACS Applied Materials & Interfaces, Год журнала: 2024, Номер unknown

Опубликована: Сен. 24, 2024

Metal adhesive synthesis typically involves heating and solvents, the resultant adhesives lack degradability suffer from recycling sustainable problems. Herein, we developed a solvent-free chemically degradable biobased (p(Elp-TA)+PVP) thioctic acid (TA), its derivative (Elp), polyvinylpyrrolidone (PVP). Through rapid acid-triggered cationic ring-opening polymerization of dithiolane at ambient conditions, p(Elp-TA)+PVP could build up strong lap shear strength 1123 kPa in air an underwater 534 to copper plate. Molecular dynamics simulations show that compared p(Elp-TA), presence appropriate amount PVP can significantly enhance binding energy molecules metal substrate, adhesion substrates was achieved through synergistically dynamic adaptive network enhanced by hydrogen bonding, reversible coordination bonding 40 ps. More importantly, applied be easily degraded reverted small-molecular-weight lipoic species. Upon exposure dithiothreitol, green reducing agent, average molecular weight quickly decrease 1603 kDa 274 Da. This constructed simple method provides promising general strategy for developing controlled recoverable natural resources.

Язык: Английский

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Advances in Stimuli-Responsive Injectable Hydrogels for Biomedical Applications

Biomaterials Science, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

The development of new multi-responsive injectable hydrogels with cascades or even synergistic effects will be great significance in the field precision medicine.

Язык: Английский

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Nano-fibrous biopolymers as building blocks for gel networks: Interactions, characterization, and applications

Advances in Colloid and Interface Science, Год журнала: 2025, Номер 338, С. 103398 - 103398

Опубликована: Янв. 9, 2025

Biopolymers derived from natural resources are highly abundant, biodegradable, and biocompatible, making them promising candidates to replace non-renewable fossil fuels mitigate environmental health impacts. Nano-fibrous biopolymers possessing advantages of entangle with each other through inter-/intra-molecular interactions, serving as ideal building blocks for gel construction. These biopolymer nanofibers often synergize nano-building enhance gels desirable functions eco-friendliness across various applications in biomedical, environmental, energy sectors. The interactions directly affect the assembly blocks, which determines structure gels, integrity connected influencing mechanical properties performance specific applications. This review focuses on four (cellulose, chitin, silk, collagen), commonly used preparations, representatives polysaccharides polypeptides. covalent non-covalent between materials have been categorized discussed relation resulting network structures properties. Nanomechanical characterization techniques, such surface forces apparatus (SFA) atomic force microscopy (AFM), employed precisely quantify intermolecular blocks. these classified correlated their act "sewing threads", connecting all establish suitable functions. aims provide a comprehensive understanding involved preparation design principles needed achieve targeted functional gels.

Язык: Английский

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Phytic acid/chitosan-assisted zwitterionic double-network hydrogels with enhanced mechanical properties, adhesion ability and ionic conductivity for wearable strain sensors

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 142841 - 142841

Опубликована: Апрель 1, 2025

Язык: Английский

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Mussel‐Inspired Molecular Strategies for Fabricating Functional Materials With Underwater Adhesion and Self‐Healing Properties

Advanced Materials, Год журнала: 2025, Номер unknown

Опубликована: Май 16, 2025

Abstract The exceptional underwater adhesion and self‐healing capabilities of mussels have fascinated researchers for over two decades. Extensive studies shown that these remarkable properties arise from a series reversible dynamic molecular interactions involving mussel foot proteins. Inspired by interaction strategies, numerous functional materials exhibiting strong performance been successfully developed. This review systematically explores the nanomechanical mechanisms mussel‐inspired interactions, mainly revealed direct force measurement techniques such as surface forces apparatus atomic microscopy. development materials, including coacervates, coatings, hydrogels, with properties, is then summarized. Furthermore, macroscopic material performances are correlated underlying mechanisms, providing valuable insights rational design next‐generation enhanced properties.

Язык: Английский

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Incorporation of multi-dynamic interactions into carboxyl graphene oxide-enhanced PVA/PAA/agarose hydrogels for multifunctional wearable sensors

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 144336 - 144336

Опубликована: Май 1, 2025

Язык: Английский

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Physical crosslinking of hydrogels: The potential of dynamic and reversible bonds in burn care

Coordination Chemistry Reviews, Год журнала: 2025, Номер 542, С. 216868 - 216868

Опубликована: Июнь 6, 2025

Язык: Английский

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Research on advanced photoresponsive azobenzene hydrogels with push–pull electronic effects: a breakthrough in photoswitchable adhesive technologies

Materials Horizons, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

This study presents azobenzene-based hydrogels for photo-controlled, reversible adhesion. The ABOMe ionic hydrogel exhibits strong adhesion, self-healing, and underwater capabilities, advancing the field of smart biomedical wearable adhesives.

Язык: Английский

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