Enhanced Effects of Polystyrene Nanoplastics and Imidacloprid on Organ Damage in Loaches(Misgurnus Anguillicaudatus): Disrupted Gene Expression Leads to Imbalance in Lipid Metabolism DOI

Jun Zhu,

Pupu Yan,

Yongxi Huang

и другие.

Опубликована: Янв. 1, 2025

Язык: Английский

Metabolic-Associated Fatty Liver Disease: The Influence of Oxidative Stress, Inflammation, Mitochondrial Dysfunctions, and the Role of Polyphenols DOI Creative Commons

Raissa Bulaty Tauil,

Paula Takano Golono,

Enzo Pereira de Lima

и другие.

Pharmaceuticals, Год журнала: 2024, Номер 17(10), С. 1354 - 1354

Опубликована: Окт. 10, 2024

Metabolic-Associated Fatty Liver Disease (MAFLD) is a clinical-pathological scenario that occurs due to the accumulation of triglycerides in hepatocytes which considered significant cause liver conditions and contributes an increased risk death worldwide. Even though possible causes MAFLD can involve interaction genetics, hormones, nutrition, lifestyle (diet sedentary lifestyle) most influential factor developing this condition. Polyphenols comprise many natural chemical compounds be helpful managing metabolic diseases. Therefore, aim review was investigate impact oxidative stress, inflammation, mitochondrial dysfunction, role polyphenols MAFLD. Some reverse part damage related or among them are anthocyanin, baicalin, catechin, curcumin, chlorogenic acid, didymin, epigallocatechin-3-gallate, luteolin, mangiferin, puerarin, punicalagin, resveratrol, silymarin. These have actions reducing plasma enzymes, body mass index, waist circumference, adipose visceral indices, lipids, glycated hemoglobin, insulin resistance, HOMA index. They also reduce nuclear factor-KB (NF-KB), interleukin (IL)-1β, IL-6, tumor necrosis factor-α (TNF-α), blood pressure, fat content, steatosis fibrosis. On other hand, they improve HDL-c, adiponectin levels, fibrogenesis markers. results show promising prevention treatment

Язык: Английский

Процитировано

8
Polystyrene microplastics induce hepatic lipid metabolism and energy disorder by upregulating the NR4A1-AMPK signaling pathway DOI
Hui‐Wen Chiu,

Chun-Wei Chu,

Chih‐Chia Huang

и другие.

Environmental Pollution, Год журнала: 2025, Номер 369, С. 125850 - 125850

Опубликована: Фев. 14, 2025

Язык: Английский

Процитировано

0
Enhanced Effects of Polystyrene Nanoplastics and Imidacloprid on Organ Damage in Loaches(Misgurnus Anguillicaudatus): Disrupted Gene Expression Leads to Imbalance in Lipid Metabolism DOI

Jun Zhu,

Pupu Yan,

Yongxi Huang

и другие.

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0