World Neurosurgery,
Год журнала:
2024,
Номер
194, С. 123538 - 123538
Опубликована: Дек. 26, 2024
Cranioplasty
is
a
common
neurosurgical
procedure
aimed
at
providing
structural
protection
to
cerebral
tissues
and
enhancing
neurological
function.
The
choice
of
implant
material,
particularly
polyetheretherketone
(PEEK)
titanium
mesh,
significantly
influences
postoperative
outcomes,
including
the
incidence
subgaleal
fluid
collections
(SFC).
This
study
investigates
SFC
associated
with
PEEK
mesh
in
cranioplasty,
identifying
risk
factors
implications
for
clinical
practice.
A
retrospective
analysis
was
conducted
on
70
patients
who
underwent
cranioplasty.
SFC,
complications,
demographic
data
were
collected
analyzed.
Statistical
comparisons
made
between
2
materials.
higher
group
(46.2%)
compared
(20.5%)
(P
=
0.023).
identified
as
an
independent
factor
SFC.
Additionally,
approximately
60%
epidural
hematoma
cases
presented
highlighting
importance
meticulous
hemostasis
during
surgery.
overall
reoperation
rate
5.7%,
consistent
existing
literature.
Although
diabetes
mellitus
did
not
show
statistically
significant
association
0.064),
its
potential
impact
complications
warrants
further
investigation.
selection
materials
cranioplasty
affects
Careful
material
selection,
comorbidities,
surgical
techniques
are
essential
improve
patient
outcomes.
Future
research
should
focus
biological
interactions
cranial
refine
guidelines
Advanced Healthcare Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 2, 2025
Medical
catheters
are
susceptible
to
biological
contamination
and
pathogen
invasion,
leading
infection
inflammatory
complications.
The
development
of
antimicrobial
coatings
for
medical
devices
has
emerged
as
a
promising
strategy.
However,
limited
functionality
the
incompatibility
between
bactericidal
properties
biosafety
remain
great
challenges.
Herein,
multifunctional
polymer
coating
(CPB-Ac)
is
created,
incorporating
an
ultrasonic-responsive
carbon
monoxide
release
unit
(CORM-Ac)
antifouling
treat
catheter-related
As-synthesized
CPB-Ac
can
be
stably
anchored
various
with
arbitrary
shapes
compositions
via
facile
UV
treatment.
Both
in
vivo
vitro
experiments
demonstrated
that
this
multi-functional
exhibits
anti-fouling,
anti-inflammatory,
broad-spectrum
antibacterial
activities
well
good
biosafety.
During
initial
implantation
phase,
units
effectively
inhibit
attachment
contaminants,
significantly
reducing
risk
thrombosis
bacterial
infection.
Once
occurs,
ultrasonic
irradiation
activate
CO
much
higher
amount
55.3
µm
than
non-ultrasound
controls,
therefore
rapidly
eliminating
bacteria
alleviating
response.
It
believed
work
may
provide
effective
method
next-generation
intelligent
against
This
study
evaluates
the
clinical
outcomes
associated
with
use
of
an
improved
polyetheretherketone
(PEEK)
cranial
plate
in
cranioplasty
surgery.
A
total
104
patients
were
involved,
significant
findings
revealing
a
reduced
incidence
postoperative
adverse
reactions
PEEK
group
(28.85%)
compared
to
conventional
(50.00%,
P
=
0.027).
Patient
satisfaction
rates
markedly
higher
cohort
(P
<
0.05).
Although
medical
expenses
for
enhanced
greater
(¥
144
600
±
21
200
vs
¥
127
400
20
100,
0.05),
there
no
notable
differences
cerebral
blood
flow
perfusion
or
survival
time
between
two
groups
>
The
conclusions
indicate
that
while
plates
incur
upfront
costs,
their
benefits
terms
safety
and
patient
satisfaction,
along
implant
stability
bone
healing,
support
practice.
Consequently,
upgraded
material
is
recommended
procedures.
