Electrochemiluminescence Mechanisms and Bioanalysis Based on Multishape Gold Nanoparticles and Visualized ATT-Au NCs

ACS Applied Materials & Interfaces, Год журнала: 2025, Номер unknown

Опубликована: Фев. 12, 2025

Herein, a visual electrochemiluminescence (ECL) luminophore, 6-azido-2-thioxanthine-coated gold nanoclusters (ATT-Au NCs), was prepared efficiently in single step, followed by comprehensive characterization of their structural, optical, and ECL properties using diverse analytical methodologies. Concurrently, nanoparticles, dimers, nanorod (Au NR) dispersions, dimers (parallel perpendicular conformations) were synthesized via chemical reduction, DNA ligation, seed growth, electrostatic adsorption organic ligands, respectively. The finite difference time domain (FDTD) modeling subsequently employed to analyze the electromagnetic field distribution surrounding these revealing that parallel notably enhanced intensity. Based on this, we constructed novel biosensor harnessed surface-plasmon-coupled (SPC-ECL) resonance energy transfer (RET) between ATT-Au NCs Au NR dimers. sensor incorporated Cu2O nanoparticles (NPs) as quenching probes precisely induce RET, leading signal being switched "off". This dual enhancement strategy achieved high signal-to-noise ratio, facilitating sensitive detection microRNA-21 (miRNA-21) with linear range 1 fM–100 nM low limit 0.28 fM. work not only extends our understanding SPC effect application RET mechanism ECL, providing theoretical foundation for further advancements field, but also highlights its considerable potential applications biomedical research clinical diagnostics.

Язык: Английский

Target-triggered dual suppression of self-enhanced ECL sensor for sensitive detection of L-Cysteine

Talanta, Год журнала: 2025, Номер 294, С. 128216 - 128216

Опубликована: Апрель 25, 2025

Язык: Английский

An electrochemiluminescence sensor based on Ru(bpy)32+@Au and GO@CdS for detection of tartrazine

Microchimica Acta, Год журнала: 2025, Номер 192(5)

Опубликована: Апрель 27, 2025

Язык: Английский