Manganese-catalyzed hydrogenation, dehydrogenation, and hydroelementation reactions

Chemical Society Reviews, Год журнала: 2022, Номер 51(11), С. 4386 - 4464

Опубликована: Янв. 1, 2022

The emerging field of organometallic catalysis has shifted towards research on Earth-abundant transition metals due to their ready availability, economic advantage, and novel properties. In this case, manganese, the third most abundant transition-metal in Earth's crust, emerged as one leading competitors. Accordingly, a large number molecularly-defined Mn-complexes been synthesized employed for hydrogenation, dehydrogenation, hydroelementation reactions. regard, catalyst design is based three pillars, namely, metal-ligand bifunctionality, ligand hemilability, redox activity. Indeed, developed catalysts not only differ chelating atoms they possess but also working principles, thereby different turnover numbers product molecules. Hence, critical assessment molecularly defined manganese terms atoms, reaction conditions, mechanistic pathway, significant. Herein, we analyze complexes catalytic activity, versatility allow multiple transformations routes convert substrates target This article will be helpful get significant insight into design, aiding design.

Язык: Английский

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Advancements in multifunctional manganese complexes for catalytic hydrogen transfer reactions

Chemical Communications, Год журнала: 2021, Номер 57(69), С. 8534 - 8549

Опубликована: Янв. 1, 2021

Manganese catalyzed hydrogen transfer reactions enabled net reductions and cascade CC- CN-bond formation reactions. The success is aided by multifunctional ligand design namely metal–ligand bifunctionality, hemilability, redox non-innocence.

Язык: Английский

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Towards ligand simplification in manganese-catalyzed hydrogenation and hydrosilylation processes

Coordination Chemistry Reviews, Год журнала: 2022, Номер 458, С. 214421 - 214421

Опубликована: Янв. 31, 2022

Язык: Английский

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Recent advances in homogeneous base-metal-catalyzed transfer hydrogenation reactions

Tetrahedron, Год журнала: 2021, Номер 98, С. 132435 - 132435

Опубликована: Сен. 8, 2021

Язык: Английский

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Manganese—New prominent actor in transfer hydrogenation catalysis

Current Opinion in Green and Sustainable Chemistry, Год журнала: 2021, Номер 31, С. 100511 - 100511

Опубликована: Май 8, 2021

Язык: Английский

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Manganese-Catalyzed Anti-Markovnikov Hydroamination of Allyl Alcohols via Hydrogen-Borrowing Catalysis

ACS Catalysis, Год журнала: 2021, Номер 11(12), С. 7060 - 7069

Опубликована: Июнь 2, 2021

Controlling the selectivity in a hydroamination reaction is an extremely challenging yet highly desirable task for diversification of amines. In this article, selective formal anti-Markovnikov allyl alcohols presented. It enables versatile synthesis valuable γ-amino alcohol building blocks. A phosphine-free Earth's abundant manganese(I) complex catalyzed under hydrogen-borrowing conditions. vast range aliphatic, aromatic amines, drug molecules, and natural product derivatives underwent successful with primary secondary allylic excellent functional group tolerance (57 examples). The catalysis could be performed on gram scale has been applied molecules. mechanistic studies revealed metal–ligand bifunctionality as well hemilability ligand backbone key design principle success catalysis.

Язык: Английский

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Ammonia borane-enabled hydrogen transfer processes: Insights into catalytic strategies and mechanisms

Green Energy & Environment, Год журнала: 2022, Номер 8(4), С. 948 - 971

Опубликована: Апрель 5, 2022

Transfer hydrogenation (TH) with in situ generated hydrogen donor is of great importance reduction reactions, and an alternative strategy to traditional processes involving pressurized molecular hydrogen. Ammonia borane (NH3BH3, AB) a promising material storage, it has attracted much attention reductive organic transformations owing its high activity, good atom economy, non-toxicity, sustainability, ease transport storage. This review focuses on summarizing the recent progress AB-mediated TH reactions diverse substrates including nitro compounds, nitriles, imines, alkenes, alkynes, carbonyl compounds (ketones aldehydes), carbon dioxide, N- O-heterocycles. Syntheses protocols (metal-containing metal-free), effect reaction parameters, product distribution, variation reactivity are surveyed, mechanism each action mode AB as well structure-activity relationships discussed detail. Finally, perspectives presented highlight challenges opportunities for AB-enabled unsaturated compounds.

Язык: Английский

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Well-Defined NNS-Mn Complex Catalyzed Selective Synthesis of C-3 Alkylated Indoles and Bisindolylmethanes Using Alcohols

The Journal of Organic Chemistry, Год журнала: 2022, Номер 87(6), С. 3989 - 4000

Опубликована: Март 8, 2022

Herein, we demonstrated Mn-catalyzed selective C-3 functionalization of indoles with alcohols. The developed catalyst can also furnish bis(indolyl)methanes from the same set substrates under slightly modified reaction conditions. Mechanistic studies reveal that is going via a borrowing hydrogen pathway. To highlight practical utility, diverse range including nine structurally important drug molecules are synthesized. Furthermore, introduced one-pot cascade strategy for synthesizing functionalized directly 2-aminophenyl ethanol and alcohol.

Язык: Английский

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The Rise of Manganese-Catalyzed Reduction Reactions

Synthesis, Год журнала: 2021, Номер 54(03), С. 517 - 534

Опубликована: Сен. 29, 2021

Abstract Recent developments in manganese-catalyzed reducing transformations—hydrosilylation, hydroboration, hydrogenation, and transfer hydrogenation—are reviewed herein. Over the past half a decade (i.e., 2016 to present), more than 115 research publications have been reported these fields. Novel organometallic compounds new reduction transformations discovered further developed. Significant challenges that had historically acted as barriers for use of manganese catalysts reactions are slowly being broken down. This review will hopefully assist developing this area, by presenting clear concise overview catalyst structures substrate published so far. 1 Introduction 2 Hydrosilylation 3 Hydroboration 4 Hydrogenation 5 Transfer 6 Conclusion Perspective

Язык: Английский

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Recent Developments in Manganese, Iron and Cobalt Homogeneous Catalyzed Synthesis of Primary Amines via Reduction of Nitroarenes, Nitriles and Carboxamides

Advanced Synthesis & Catalysis, Год журнала: 2023, Номер 365(7), С. 948 - 964

Опубликована: Фев. 18, 2023

Abstract The preparation of primary amines attracts huge attention in the molecular synthetic community. Indeed, play a crucial role chemistry as they are important substructures amount drug molecules, agrochemicals, dyes and materials. Compared to stoichiometric reductions using metal hydride based reagents, catalyzed reduction nitroarenes, nitriles carboxamides appears be an attractive option, mainly when associated first row transition metals such manganese, iron, or cobalt. In this short review, we illustrate progress achieved homogeneous hydrogenation, hydrogen transfer, borrowing hydrosilylation carboxamides. magnified image

Язык: Английский

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