Methanol for Hydrogenation and Methylation of Carbonyls: Advances and Challenges in Homogeneous Catalysis DOI
Sanjay Pratihar,

Manohar Shivaji Padmor

Synlett, Год журнала: 2024, Номер 35(20), С. 2346 - 2366

Опубликована: Окт. 18, 2024

Abstract The catalytic dehydrogenation of methanol to give formaldehyde or formic acid, followed transfer hydrogenation and/or tandem (de)hydrogenation for the and C-methylation carbonyls, offers advantages over traditional methods, including milder reaction conditions, improved safety, greater selectivity, enhanced sustainability. This account provides a comprehensive overview homogeneous catalysts reported various substrates, ketones, chalcones, esters, amides, using as both hydrogen donor methylation source. We provide specific examples mechanistic insights each strategy, offering thorough concise recent advancements from 2014 2024. 1 Introduction 2 Methanol Activation Strategies 3 Hydrogenation Carbonyls 4 Methylation 5 Outlook Summary

Язык: Английский

Oxygen-Dependent Ligand-Controlled Iron-Catalyzed Chemoselective Synthesis of Olefins and Vinyl Nitriles DOI
Amit Kumar Guin, Subhajit Chakraborty,

Subhankar Khanra

и другие.

Organic Letters, Год журнала: 2024, Номер 26(13), С. 2540 - 2545

Опубликована: Март 28, 2024

An oxygen-dependent ligand-controlled chemoselective synthesis of vinyl nitriles and E-olefins by coupling a variety alcohols benzyl cyanides, catalyzed well-characterized, air-stable, easy-to-prepare Fe(II) catalyst (1a) bearing redox-active arylazo pincer (L1a) is reported. The azo-moiety the ligand backbone acts as an electron hydrogen reservoir, enabling 1a to efficiently produce broad spectrum in moderate good yields selectively under oxygen argon atmosphere, respectively.

Язык: Английский

Процитировано

6

Utilization of ruthenium(0) for σ-bond activation: Formation of organoruthenium complexes and emergence of their catalytic activity via in situ Ru-C bond cleavage DOI
M. Das, Aparajita Mukherjee,

Anannya Saha

и другие.

Journal of Organometallic Chemistry, Год журнала: 2025, Номер unknown, С. 123567 - 123567

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

0

Microwave‐Assisted Metal‐Free C─N Coupling for The Synthesis of Common Ligand Precursors of Organometallic Complexes DOI
V. P. Jaiswal,

Ashu Singh,

Naveen Kumar

и другие.

ChemistrySelect, Год журнала: 2025, Номер 10(19)

Опубликована: Май 1, 2025

Abstract This study presents a microwave‐assisted, metal‐free approach for the fast and selective synthesis of pyridine‐functionalized N ‐heterocyclic ligand precursors. Efficient synthetic methods are important in development cost‐effective transition metal complexes commonly used as catalysts various applications. Traditional forming C–N C–C bonds require long reaction times harsh conditions, whereas microwave heating accelerates by significantly reducing time temperature, under metal‐ additive‐free conditions. has enabled mono‐ di‐substituted pyridine‐based synthons starting from 2,6‐dibromopyridine well 2,6‐dichloropyridine. The also applies to other substrates, delivering high‐purity ligands 5–15 min. Notably, this method provides an alternative cross‐coupling reactions, eliminating requirement copper catalysts, more sustainable efficient conventional strategies. prepared using microwave‐assisted reported here have been utilized prepare some common preparation organometallic complexes.

Язык: Английский

Процитировано

0

Room Temperature Transfer Hydrogenation of Aldehydes Using Methanol Catalyzed by Iridium(III) Pyridylidene-Indole Complex DOI

Sandip Bapu Khatal,

Manohar Shivaji Padmor,

Megha Mariet

и другие.

Chemical Communications, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

An air- and moisture-stable (L)Ir( iii )Cp* catalyst with electron-rich pyridylidene–indole ligands enables efficient, selective transfer hydrogenation of aldehydes to alcohols using methanol at low temperatures (10–25 °C).

Язык: Английский

Процитировано

0

Base-controlled NHC-Ru-catalyzed transfer hydrogenation and α-methylation/transfer hydrogenation of ketones using methanol DOI
Ming Huang, Xiuju Cai, Yan Liu

и другие.

Chinese Chemical Letters, Год журнала: 2023, Номер 35(7), С. 109323 - 109323

Опубликована: Ноя. 19, 2023

Язык: Английский

Процитировано

4

Microwave-assisted Transfer Hydrogenation of Carbonyl and Nitro Compounds by Bimetallic Ru(II) cymene Complexes DOI
Ramaswamy Murugavel, Gopal Deshmukh

Synlett, Год журнала: 2024, Номер unknown

Опубликована: Март 25, 2024

Abstract We report an investigation of the microwave-assisted catalytic transfer hydrogenation (TH) carbonyl and nitro compounds by employing Ru(II) complexes: bimetallic [(p-cymene)2(RuCl)2L1]2X (X = BF4 (Cat2); X PF6 (Cat3)) mononuclear [(p-cymene)(RuCl)L2]BF4 (Cat4) (where L1 N,N′-(3,3′,5,5′-tetraisopropyl-[1,1′-biphenyl]-4,4′-diyl)bis(1-(pyridin-2-yl)methanimine) L2 N-(2,6-diisopropylphenyl)-1-(pyridin-2-yl)methanimine). At a low catalyst loading 0.01 mol% (Cat2/Cat3), broad range substrates, comprising aromatic as well aliphatic ketones aldehydes, undergo TH reaction in short time just 10 minutes. Additionally, chemoselective nitroaromatic is achieved under microwave irradiation presence Cat2 within 5 Control experiments demonstrate that heating conditions outperform conventional terms improved activity efficiency. The used at very 0.001 to achieve high TONs TOFs 7.7 × 104 2.3 105 h–1, respectively, for reaction. Spectrometry involving trapping intermediates are propose mechanism compounds.

Язык: Английский

Процитировано

1

Ruthenium catalyzed dehydrogenative α-C–H functionalization of β-naphthol using alcohols: a metal–ligand cooperative borrowing hydrogen approach DOI
Amit Kumar Guin, Santana Chakraborty,

Subhankar Khanra

и другие.

Catalysis Science & Technology, Год журнала: 2024, Номер 14(12), С. 3540 - 3549

Опубликована: Янв. 1, 2024

Chemoselective α-C–H functionalization of β-naphthol is achieved with inexpensive and readily available alcohols using a well-defined, air-stable, easy-to-prepare Ru( ii )-catalyst (1a) bearing redox-active tridentate pincer ( L 1a).

Язык: Английский

Процитировано

0

Methanol for Hydrogenation and Methylation of Carbonyls: Advances and Challenges in Homogeneous Catalysis DOI
Sanjay Pratihar,

Manohar Shivaji Padmor

Synlett, Год журнала: 2024, Номер 35(20), С. 2346 - 2366

Опубликована: Окт. 18, 2024

Abstract The catalytic dehydrogenation of methanol to give formaldehyde or formic acid, followed transfer hydrogenation and/or tandem (de)hydrogenation for the and C-methylation carbonyls, offers advantages over traditional methods, including milder reaction conditions, improved safety, greater selectivity, enhanced sustainability. This account provides a comprehensive overview homogeneous catalysts reported various substrates, ketones, chalcones, esters, amides, using as both hydrogen donor methylation source. We provide specific examples mechanistic insights each strategy, offering thorough concise recent advancements from 2014 2024. 1 Introduction 2 Methanol Activation Strategies 3 Hydrogenation Carbonyls 4 Methylation 5 Outlook Summary

Язык: Английский

Процитировано

0