Advanced Synthesis & Catalysis,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 8, 2024
Abstract
Herein,
we
report
the
development
of
photoredox‐catalyzed
N−H
insertion
sulfoxonium
ylides
with
amines
via
oxidative
single‐electron
transfer
(SET).
These
reactions
exhibit
broad
substrate
scope
(32
examples)
and
offer
operationally
simple,
scalable
procedures
for
accessing
α
‐ketoamides
in
a
single
step.
Mechanistic
studies
control
experiments
confirm
participation
photogenerated
carbon
radical
facilitating
(SET)
from
to
initiate
reaction.
Chemical Communications,
Год журнала:
2024,
Номер
60(30), С. 4076 - 4079
Опубликована: Янв. 1, 2024
This
work
discloses
a
new
methodology
for
the
site-selective
direct
installation
of
nitro
group
at
benzene
ring
2
H
-indazoles
with
excellent
selectivity
towards
synthesis
7-nitroindazole
derivatives.
Abstract
The
synthesis
of
acylmethylatated
pyrrolo‐quinazolinones
was
developed
via
photo‐induced
cascade
radical
addition/cyclization
N
‐(but‐3‐enyl)quinazolin‐4(3
H
)‐ones
with
sulfoxonium
ylides
using
4CzIPN
as
the
photocatalyst.
This
approach
also
suitable
for
construction
piperidino‐quinazolinones.
protocol
features
mild
conditions,
convenient
operation,
broad
substrate
scope
and
good
functional
group
compatibility.
Advanced Synthesis & Catalysis,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 8, 2024
Abstract
Herein,
we
report
the
development
of
photoredox‐catalyzed
N−H
insertion
sulfoxonium
ylides
with
amines
via
oxidative
single‐electron
transfer
(SET).
These
reactions
exhibit
broad
substrate
scope
(32
examples)
and
offer
operationally
simple,
scalable
procedures
for
accessing
α
‐ketoamides
in
a
single
step.
Mechanistic
studies
control
experiments
confirm
participation
photogenerated
carbon
radical
facilitating
(SET)
from
to
initiate
reaction.
