Combination of photocatalytic proton-coupled electron transfer and spin-center shift: direct C-H benzylation of N-heteroarenes with benzaldehydes in continuous-flow
Jia-Cheng Hou,
Jun Jiang,
Hui Dai
и другие.
Science China Chemistry,
Год журнала:
2025,
Номер
68(5), С. 1945 - 1951
Опубликована: Фев. 24, 2025
Язык: Английский
Aldehyde–Olefin Couplings Via Sulfoxylate-Mediated Oxidative Generation of Ketyl Radical Anions
Journal of the American Chemical Society,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 20, 2024
Ketyl
radicals
are
valuable
reactive
intermediates
because
they
allow
carbonyl
chemistry
to
be
extended
beyond
traditional
electrophilic
reactivity
through
simple
single-electron
reduction
a
nucleophilic
radical.
However,
this
pathway
is
challenging
due
the
large
negative
potentials
of
carbonyls,
thus
requiring
highly
reducing
conditions.
Herein,
we
describe
development
an
alternative
strategy
access
ketyl
from
aldehydes,
which
avoids
by
instead
proceeding
via
oxidation
and
desulfination
α-hydroxy
sulfinates.
These
redox-active
aldehyde
adducts
generated
Язык: Английский
Successors of SmI2: Next Generation Metal, Photo and Electro‐Catalysis for Reductive Organic Synthesis
European Journal of Organic Chemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 18, 2025
Abstract
Electron
transfer
plays
a
pivotal
role
in
generating
radical
intermediates
which
are
pillars
of
constructing
complex
molecular
structure.
Since
the
introduction
by
Kagan,
SmI
2
played
key
single
electron
mediated
reductive
transformations.
Despite
significant
applications
high
profile
synthesis
natural
products,
usage
was
discoursed
due
to
weight
reagent,
less
solubility
and
most
importantly
stoichiometric
nature
reactions.
Recent
years
have
witnessed
renaissance
photo‐and
electro‐catalytic
reactions
more
sustainable
nature.
A
handful
these
showed
potential
replace
as
greener
alternative.
This
prospective
article
aims
demonstrate
reducing
systems
use
.
Язык: Английский
Three-component alkenylcarboxylation of two distinct alkenes with CO2 via photoinduced palladium catalysis
Chinese Chemical Letters,
Год журнала:
2025,
Номер
unknown, С. 111304 - 111304
Опубликована: Май 1, 2025
Язык: Английский
Catalytic Aldehyde–Alkyne Couplings Triggered by Ketyl Radicals
Organic Letters,
Год журнала:
2024,
Номер
26(46), С. 9949 - 9954
Опубликована: Ноя. 8, 2024
A
general
and
flexible
platform
for
catalytic
aldehyde-alkyne
couplings
triggered
by
ketyl
radicals
is
described.
This
open-shell
strategy
necessitates
only
a
quantity
of
photoredox
catalyst,
along
with
Hünig's
base
(DIPEA)
as
halogen
atom
transfer
reagent.
The
reaction
proceeds
through
sequential
steps
involving
activation,
transfer,
radical
addition.
carbonyl-alkyne
coupling
exhibits
wide
substrate
scope
functional
group
compatibility
has
been
successfully
applied
to
the
late-stage
modification
complex
architectures.
Язык: Английский