Asian Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Май 26, 2025

Abstract Photo‐assisted, iron‐catalyzed C─H functionalizations represent nowadays a sustainable tool to develop unprecedented transformations, unviable by common catalytic organometallic approaches promoted transition metals. In fact, the use of this new technology allows for more efficient synthetic transformations increasing chemo‐, regio‐ and site‐selectivity catalysis while reducing formation by‐products shortening reaction times. Further, replacement precious transition‐metals with iron catalysts is highly desiderable development environmentally‐friendly methods. Within review, we aim summarize latest achievements combining most abundant safe metal in “outer‐sphere” functionalization reactions mediated light C─C C─Het bonds, including challenging C─N, C─P, C─B C─S bonds. Particular attention has been directed toward description mechanistic aspects application methods late‐stage polymers, marketed drugs, biologically‐active compounds materials.

Язык: Английский