Occurrence and Toxicity Mechanisms of Perfluorononanoic Acid, Perfluorodecanoic Acid, and Perfluoroundecanoic Acid in Fish: A Review DOI Creative Commons
Emma Ivantsova, Amany Sultan, Christopher J. Martyniuk

и другие.

Toxics, Год журнала: 2025, Номер 13(6), С. 436 - 436

Опубликована: Май 26, 2025

Per- and polyfluoroalkyl substances (PFAS) are used in consumer products manufacturing. Perfluorononanoic acid (PFNA), perfluorodecanoic (PFDA), perfluoroundecanoic (PFUnDA) long-chain PFAS composed of 9, 10, 11 carbons, respectively, which exert sublethal toxicity to aquatic species. Here, we review the data regarding environmental fate ecotoxicology these understudied fish. The objectives this study were (1) compile literature compare physiological or molecular signaling pathways disrupted by PFNA, PFDA, PFUnDA; (2) uncover potential biomarkers longer-chain using gene ontology computational approaches shed light on their mechanism action. Studies show that have a range effects fish, including developmental issues, changes expression, behavioral modifications. Based our review, PFNA has been studied more frequently fish compared PFDA however, longer-chained proposed pose greater toxicity. approach, prominent affected include insulin [“Insulin -> CEBPA/CTNNB/FOXA/FOXO”, “Insulin STAT Expression Targets”], immune system [“TNF Targets”, “IL6 “IL2 growth hormone/prolactin [“GH1/PRLR “PRL/GHR “PRL/PRLR Targets”]. Several transcripts related cholesterol metabolism also PFNA. This summarizes current knowledge distribution, fate, PFUnDA teleost highlighting responses could aid assessing future studies.

Язык: Английский

Per- and Poly-Fluoroalkyl Substances, and Organophosphate Flame Retardants in the Upper Yangtze River: Occurrence, Spatiotemporal Distribution, and Risk Assessment DOI Creative Commons
Wen Sun,

Zhiyou Fu,

Yueyue Liu

и другие.

Toxics, Год журнала: 2025, Номер 13(2), С. 116 - 116

Опубликована: Фев. 1, 2025

Contaminants of Emerging Concern (CECs), including per- and polyfluoroalkyl substances (PFASs) organophosphate flame retardants (OPFRs), have raised global concerns due to their persistence, bioaccumulation potential, toxicity. This study presents a comprehensive investigation the occurrence, spatiotemporal distribution, potential sources, ecological human health risks associated with 18 PFASs 9 OPFRs in surface waters upper Yangtze River, China. The water samples were collected from main stream five major tributaries (Min, Jinsha, Tuo, Jialing, Wu Rivers) 2022 2023. total concentration ranged 16.07 927.19 ng/L, 17.36 190.42 respectively, consistently higher observed compared tributaries. Ultra-short-chain (e.g., TFMS) halogenated TCPP) predominant compounds, likely originating industrial discharges, wastewater effluents, other anthropogenic sources. Ecological risk assessments indicated low-to-moderate at most sampling sites, near discharge points. Human evaluations suggested negligible non-carcinogenic but identified carcinogenic OPFR exposure for adults specific locations, particularly Leshan city. highlights importance understanding fate impacts provides valuable insights developing targeted pollution control strategies management measures.

Язык: Английский

Процитировано

0
The Distribution and Seasonality of Per- and Polyfluoroalkyl Substances (PFAS) in the Vertical Water Column of a Stratified Eutrophic Freshwater Lake DOI Open Access
Patrick R. Gorski

Environments, Год журнала: 2025, Номер 12(2), С. 48 - 48

Опубликована: Фев. 4, 2025

The vertical distribution and potential variability of Per- Polyfluoroalkyl substances (PFAS) in the water column lacustrine systems is important to know for sampling monitoring purposes, but could also relate details their fate, transport, distribution. In this study, a eutrophic freshwater lake (Lake Monona, Madison, WI, USA) was sampled vertically PFAS during summer stratification at several depths (surface microlayer 1 m from bottom) then monitored four dates three following year assess seasonality. concentration did not exhibit or large column. However, seasonal variation detected, as well an increase related drought conditions. This study suggests that surface grab sample may be sufficient representative basic PFAS. But single provide complete understanding lake, multiple samples should taken capture understand events.

Язык: Английский

Процитировано

0
Enhanced removal of perfluorooctanoic acid and perfluorooctane sulphonic acid by direct current in iron-based constructed wetlands DOI

Haoqin Ma,

Guorui Kong,

Chen Chen

и другие.

Water Research, Год журнала: 2025, Номер 277, С. 123302 - 123302

Опубликована: Фев. 15, 2025

Язык: Английский

Процитировано

0
Sand dollars (Mellita quinquiesperforata): A new bioindicator for tracking PFAS in coastal waters DOI
John A. Bowden, Qaim Mehdi,

Lauren E. Blackman

и другие.

Marine Pollution Bulletin, Год журнала: 2025, Номер 213, С. 117673 - 117673

Опубликована: Фев. 17, 2025

Язык: Английский

Процитировано

0
Background PFAS Concentrations in Surface Soil of Massachusetts and Northern New England: Regional and Global Source Patterns and Regulatory Relevance DOI

Lisa McIntosh,

Catharine Rockwell,

Samantha Olney

и другие.

Remediation Journal, Год журнала: 2025, Номер 35(2)

Опубликована: Янв. 1, 2025

ABSTRACT Surface soil (0–15 cm below grade) was collected from 100 locations at 25 properties across Massachusetts and analyzed for 36 per‐ polyfluoroalkyl substances (PFAS). Perfluorooctane sulfonic acid (PFOS) perfluorooctanoic (PFOA) were detected in every sample the highest concentrations relative to other PFAS. Perfluorinated carboxylic acids more common than perfluoroalkyl acids, PFAS significantly correlated with organic carbon content. No fluorotelomers, perfluoroalkane sulfonamide or sulfonyl substances, ether chloropolyfluoroalkyl detected. Comparison results northern New England (Maine, Vermont, Hampshire) exhibit a consistent pattern. PFOS PFOA are most commonly found concentrations. The predominant present their as function of chain length different regional industrial sources like deposition estimates resulting global emissions, including outside North America, atmospheric precursor degradation. Anthropogenic background may exceed cleanup standards based on leaching groundwater, investigation remediation liabilities property owners even though no onsite release has occurred. Given ubiquity today, anthropogenic should be considered during promulgation standards.

Язык: Английский

Процитировано

0
Per- and Polyfluoroalkyl Substances (PFAS) Composition and Distribution in Surface Water of the Miccosukee Indian Reservation, Everglades and Tributaries in the Coastal Environment of Miami, Florida DOI

C. W. Heath,

A. R. Castañeda,

Edward Ornstein

и другие.

Environmental Research, Год журнала: 2025, Номер unknown, С. 121627 - 121627

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0
Occurrence and Toxicity Mechanisms of Perfluorononanoic Acid, Perfluorodecanoic Acid, and Perfluoroundecanoic Acid in Fish: A Review DOI Creative Commons
Emma Ivantsova, Amany Sultan, Christopher J. Martyniuk

и другие.

Toxics, Год журнала: 2025, Номер 13(6), С. 436 - 436

Опубликована: Май 26, 2025

Per- and polyfluoroalkyl substances (PFAS) are used in consumer products manufacturing. Perfluorononanoic acid (PFNA), perfluorodecanoic (PFDA), perfluoroundecanoic (PFUnDA) long-chain PFAS composed of 9, 10, 11 carbons, respectively, which exert sublethal toxicity to aquatic species. Here, we review the data regarding environmental fate ecotoxicology these understudied fish. The objectives this study were (1) compile literature compare physiological or molecular signaling pathways disrupted by PFNA, PFDA, PFUnDA; (2) uncover potential biomarkers longer-chain using gene ontology computational approaches shed light on their mechanism action. Studies show that have a range effects fish, including developmental issues, changes expression, behavioral modifications. Based our review, PFNA has been studied more frequently fish compared PFDA however, longer-chained proposed pose greater toxicity. approach, prominent affected include insulin [“Insulin -> CEBPA/CTNNB/FOXA/FOXO”, “Insulin STAT Expression Targets”], immune system [“TNF Targets”, “IL6 “IL2 growth hormone/prolactin [“GH1/PRLR “PRL/GHR “PRL/PRLR Targets”]. Several transcripts related cholesterol metabolism also PFNA. This summarizes current knowledge distribution, fate, PFUnDA teleost highlighting responses could aid assessing future studies.

Язык: Английский

Процитировано

0