Small-sized
graphite-coated
CeO
2
NPs
with
multi-defective
structures
and
desirable
oxidase-like
activity
were
synthesized
by
an
eco-friendly,
simple,
sustainable
method.
RSC Advances,
Год журнала:
2024,
Номер
14(38), С. 27873 - 27882
Опубликована: Янв. 1, 2024
Copper-doped
carbon
dots
(Cu-CDs)
are
safe
and
act
like
peroxidase.
They
kill
bacteria
E.
coli
S.
aureus
by
turning
H
2
O
into
powerful
·OH.
This
green
nanozyme
could
be
a
new
way
to
make
antibacterial
materials.
Biosensors and Bioelectronics X,
Год журнала:
2024,
Номер
19, С. 100514 - 100514
Опубликована: Июль 5, 2024
Nanozyme
cascade
have
garnered
substantial
interest
in
recent
years
due
to
their
distinctive
properties.
However,
the
conventional
stepwise
reaction
undergoes
tedious
two-step
operation
process
owing
incompatibility
of
conditions.
Moreover,
most
reported
nanozymes
exhibit
favorable
catalytic
performance
only
acidic
medium,
which
greatly
restricts
usage
especially
biochemical
analysis.
To
address
above
challenges,
we
developed
gold
nanoparticles/calcium
hexacyanoferrate
(Ⅲ)/nitrogen-doped
graphitic
alkyne
(AuNPs/CaHF
NPs/N-GDY)
nanozyme
with
superior
activity
at
neutral
pH
comparable
that
acidic.
Specifically,
AuNPs/CaHF
NPs/N-GDY
simultaneously
possessed
glucose
oxidase-like
(GOx)
and
peroxidase-like
(HRP)
activities,
could
induce
one-step
presence
glucose,
resulting
5-fold
enhancement
efficiency
compared
reaction.
Besides,
tripedal
DNA
walker
was
equipped
sufficient
walking
legs
walk
on
directional
highly
controllable
stepped
track,
reducing
possibility
derailment
boosting
efficiency.
As
a
proof
concept,
novel
electrochemical
biosensor
constructed
for
miRNA-21
sensitive
detection
physiological
pH,
successfully
applied
human
serum
samples
as
well
practical
intracellular
analysis,
offering
great
potential
biomedical
research
clinical
diagnosis.
Molecular Pharmaceutics,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 1, 2024
Intracellular
copper
ion
homeostasis
has
become
an
attractive
target
for
cancer
therapy.
Herein,
we
report
a
2,2'-dipicolylamine
(DPA)
functionalized
polyglutamate
derivative
(PDHB)
which
is
capable
of
rapidly
forming
PDHB-copper
complex
(PDHB@Cu)
due
to
the
strong
coordination
ability
pendant
DPA
with
Cu
Small-sized
graphite-coated
CeO
2
NPs
with
multi-defective
structures
and
desirable
oxidase-like
activity
were
synthesized
by
an
eco-friendly,
simple,
sustainable
method.