Advances of Metal‐Based Nanomaterials in the Prevention and Treatment of Oral Infections
Advanced Healthcare Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 17, 2025
The
complicated
environment
of
the
oral
cavity
presents
significant
challenges
to
traditional
antibacterial
approaches,
which
has
driven
exploration
novel
therapeutic
strategies.
Metal-based
nanomaterials
(MNMs),
with
diverse
mechanisms
(e.g.,
membrane
disruption,
oxidative
stress)
and
evolution
from
empirical
theory-guided
design,
exhibit
immense
potential.
This
review
introduces
pioneering
Hierarchical
Response
Strategy
Framework,
systematically
classifying
MNM
systems
into
three
progressive
levels:
Primary
category,
comprising
MNMs
that
exert
spontaneous
effects
based
on
inherent
physicochemical
properties
ion
release);
Secondary
including
precisely
controlled
actions
by
microenvironmental
or
stimulus-responsive
light-induced
ROS);
Tertiary
encompassing
integrate
regenerative
functions
for
multidimensional
therapy
remineralization).
Through
this
framework,
authors
elucidate
MNMs'
transition
single-function
precision-controlled,
multifunctional
synergy,
analyze
impact
metal
elements
structural
design
efficacy,
summarize
their
applications
in
dental
caries,
endodontic
infections,
periodontal
disease,
etc.
framework
offers
a
perspective
existing
research
theoretical
foundation
rational
next-generation
precise,
smart,
comprehensive
anti-infective
materials.
Язык: Английский
Gelatin Assisted Green Synthesis of Silver Ferrite Nanoparticles Using Capparis Cartilaginea Extract for Enhanced Antimicrobial Activity
ChemistrySelect,
Год журнала:
2025,
Номер
10(17)
Опубликована: Апрель 29, 2025
Abstract
In
this
study,
Capparis
cartilaginea
extract
was
used
as
a
reducing
and
stabilizing
agent
to
perform
an
eco‐friendly
synthesis
of
gelatin‐coated
silver
ferrite
nanoparticles
(GAgFeO
2
).
The
had
crystallite
size
approximately
25
nm
were
characterized
via
X‐ray
diffraction
(XRD),
Fourier
transform
infrared
spectroscopy
(FTIR),
field‐emission
scanning
electron
microscopy
(FESEM),
Brunauer–Emmett–Teller
(BET)
surface
area
analysis.
BET
analysis
revealed
that
the
gelatin
coating
results
in
GAgFeO
having
slightly
lower
specific
(22.87
m
/g),
than
AgFeO
had.
exhibited
moderate
stability
with
zeta
potential
−17.5
mV,
while
showed
higher
−23.8
indicating
stronger
electrostatic
repulsion
enhanced
colloidal
stability.
Antimicrobial
tests
26
mm
inhibition
zone
against
MRSA,
14
Pseudomonas
aeruginosa
,
16
Salmonella
Typhimurium
outperforming
uncoated
nanoparticles.
minimum
inhibitory
concentration
(MIC)
Candida
albicans
0.062
mg/mL
antifungal
potential.
These
demonstrate
superior
antimicrobial
efficacy
well
their
application
medical
environmental
fields.
Язык: Английский
Sustainable synthesis of iron-doped manganese oxide nanoparticles for effective photo-accelerated detoxification of tetracycline
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Май 24, 2025
The
widespread
use
of
antibiotics
has
severely
impacted
water
bodies
and
ecosystems,
necessitating
well-designed
photocatalysts
for
effective
degradation.
In
this
regard,
present
work
reports
the
synthesis
MnO2:xFe3+
(MF-x,
x
=
0,
2,
4,
6,
8,
10)
nanoparticles
via
bio-mediated
process
using
Tridax
procumbens
as
reducing
stabilizing
agents.
Various
physicochemical
approaches
confirmed
structural,
optical,
morphological
properties
MF-x
nanoparticles,
revealing
a
reduced
optical
bandgap
(2.06-0.97
eV)
visible-light
photocatalysis.
PXRD
analysis
reveals
cubic
crystalline
nature
belonging
to
space
group
number
206
(I
a-3)
with
crystallite
sizes
ranging
39-70
nm,
which
was
further
refined
Rietveld
method
acceptable
χ2
value
2.3
doped
sample.
Raman
spectra
existence
Fg
Eg
+
active
modes
from
bixbyite
structure
corresponding
I
a-3.
Furthermore,
FESEM
TEM
analyses
showed
highly
uniform
porous
morphology
evaluated
particle
in
agreement
results.
Additionally,
quantitative
aspects
precursor
elements
were
through
XPS
studies.
photocatalytic
activity
MF-10
degrading
Tetracycline
hydrochloride
(TC-HCl)
under
optimized
pH,
catalyst
dosage,
TC-HCl
concentration
visible
light.
Results
show
that
weight
(100
mg)
as-synthesized
exhibit
high
performance
94.23%
degradation
against
20
ppm
90
min.
On
other
hand,
pH
variation
reusability
test
indicated
efficiency
significant
at
neutral
5th
cycle
(64.28)
authenticated
by
pHPZC
evaluation
(7.55).
Thus,
showcased
potential
application
MnO2:
Fe3+
low-cost
environmentally
friendly
material
treatment
applications.
Язык: Английский