4-Benzyl-2-(3-(4-fluorophenyl)-2-oxopropyl)-6-phenyl pyridazin-3(2H)-one as a Carbon Steel Corrosion Inhibitor in an Acidic Environment: Electrochemical, Spectroscopic, Thermodynamic, and Quantum Chemical Assessments

Journal of Bio- and Tribo-Corrosion, Год журнала: 2024, Номер 10(3)

Опубликована: Июнь 18, 2024

Язык: Английский

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Investigation of a pyridazinone derivative as a corrosion inhibitor for carbon steel in acidic conditions using experimental and theoretical methods

International Journal of Electrochemical Science, Год журнала: 2024, Номер 19(9), С. 100732 - 100732

Опубликована: Июль 22, 2024

The anti-corrosive properties of the newly synthesized compound pyridazinone, especially 2-(3-(4-fluorophenyl)-2-oxopropyl)-4-(3-nitrobenzyl)-6-phenylpyridazin-3(2 H)-one (FOPP), on carbon steel in a 1 M hydrochloric acid solution were thoroughly investigated. We used multiple techniques, including potentiodynamic polarization (PDP), electrochemical impedance spectroscopy (EIS), surface morphology analysis, contact angle measurements, UV–visible spectrometry, and quantum chemical calculations. maximum corrosion inhibition efficiency FOPP was found to be 96.3 % at 10−3 concentration 303 K temperature. PDP studies showed that acts as mixed-type inhibitor with anodic predominance. hydrophobicity metal studied considerable improvement by coating using technique. Scanning electron microscopy (SEM) energy dispersive (EDX) confirm results obtained two methods theoretical chemistry, namely density functional analysis (DFT) molecular dynamics simulation, gain better understanding interactions between ability this adhere iron form protective film.

Язык: Английский

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NLRP3 and autophagy in retinal ganglion cell inflammation in age-related macular degeneration: potential therapeutic implications

International Journal of Ophthalmology, Год журнала: 2024, Номер 17(8), С. 1531 - 1544

Опубликована: Июль 24, 2024

Retinal degenerative diseases were a large group of characterized by the primary death retinal ganglion cells (RGCs). Recent studies had shown an interaction between autophagy and nucleotide-binding oligomerization domain-like receptor 3 (NLRP3) inflammasomes, which may affect RGCs in diseases. The NLRP3 inflammasome was protein complex that, upon activation, produces caspase-1, mediating apoptosis promoting occurrence development Upregulated could inhibit while inhibited can promote leaded to accelerated emergence drusen lipofuscin deposition under neurosensory retina. activated further autophagy, thus forming vicious cycle that damage RGCs. This review discussed relationship its effects on age-related macular degeneration, providing new perspective direction for treatment

Язык: Английский

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Integrated bioinformatics analysis of shared biomarkers and mechanisms in united airway allergic disease and Alzheimer's disease

Gene Reports, Год журнала: 2025, Номер 40, С. 102244 - 102244

Опубликована: Май 5, 2025

Язык: Английский

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