Towards load-bearing biomedical titanium-based alloys: From essential requirements to future developments

Progress in Materials Science, Год журнала: 2024, Номер 144, С. 101277 - 101277

Опубликована: Март 8, 2024

The use of biomedical metallic materials in research and clinical applications has been an important focus a significant area interest, primarily owing to their role enhancing human health extending lifespan. This article, particularly on titanium-based alloys, explores exceptional properties that can address bone issues amid the growing challenges posed by aging population. Although stainless steel, magnesium-based cobalt-based other are commonly employed medical applications, limitations such as toxic elements, high elastic modulus, rapid degradation rates limit widespread applications. Therefore, alloys have emerged top-performing materials, gradually replacing counterparts various article extensively examines highlights along with in-depth discussion currently utilized inherent limitations. To begin with, essential requirements for load-bearing biomaterials introduced. Then, summarized compared. Afterward, microstructure, properties, preparations explored. Furthermore, surface modification methods discussed enhance biocompatibility, wear resistance corrosion resistance. Finally, proposes development path conjunction additive manufacturing novel alloy nitinol.

Язык: Английский

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A critical review on metal-organic frameworks (MOFs) based nanomaterials for biomedical applications: Designing, recent trends, challenges, and prospects

Heliyon, Год журнала: 2024, Номер 10(3), С. e25521 - e25521

Опубликована: Фев. 1, 2024

Nanomaterials (NMs) have garnered significant attention in recent decades due to their versatile applications a wide range of fields. Thanks tiny size, enhanced surface modifications, impressive volume-to-surface area ratio, magnetic properties, and customized optical dispersion. NMs experienced an incredible upsurge biomedical including diagnostics, therapeutics, drug delivery. This minireview will focus on notable examples that tackle important issues, demonstrating various aspects such as design, synthesis, morphology, classification, use cutting-edge applications. Furthermore, we classified outlined the distinctive characteristics advanced nanoscale particles hybrid NMs. Meanwhile, emphasize potential metal-organic frameworks (MOFs), highly group These MOFs gained recognition promising candidates for bio-applications, bioimaging, biosensing, antiviral therapy, anticancer nanomedicines, theranostics, immunotherapy, photodynamic photothermal gene Although shown great field, clinical is still limited by issues stability, cytotoxicity, biocompatibility, health concerns. review article provides thorough analysis offering valuable insights researchers investigating explore new development, expansion opportunities. Remarkably, ponder prospects nanocomposites conjunction with current technology.

Язык: Английский

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Therapeutic Potential of Microneedle Assisted Drug Delivery for Wound Healing: Current State of the Art, Challenges, and Future Perspective

AAPS PharmSciTech, Год журнала: 2025, Номер 26(1)

Опубликована: Янв. 8, 2025

Язык: Английский

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Oxygen Activation Biocatalytic Precipitation Strategy Based on a Bimetallic Single-Atom Catalyst for Photoelectrochemical Biosensing

Analytical Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 30, 2025

The traditional biocatalytic precipitation (BCP) strategy often required the participation of H2O2, but H2O2 had problem self-decomposition, which prevented its application in quantitative analysis. This work first found that a bimetallic single-atom catalyst (Co/Zn–N–C SAC) could effectively activate dissolved O2 to produce reactive oxygen species (ROS) due superior oxidase (OXD)-like activity. Experimental investigations demonstrated Co/Zn–N–C SAC preferred highly active hydroxyl radicals (•OH), oxidized 3-amino-9-ethyl carbazole (AEC) reddish-brown insoluble precipitates. Based on this property, unique oxygen-activated photoelectrochemical (PEC) biosensor was developed for chloramphenicol (CAP) detection. Cesium platinum bromide nanocrystals (Cs2PtBr6 NCs) were new type halide perovskite with lead-free, narrow band gaps, and water-oxygen resistance. Cs2PtBr6 NCs showed excellent cathodal PEC performance without an exogenous coreactant used As "proof-of-concept application", introduced onto surface by using CAP dual-aptamer sandwich strategy. activated ROS, AEC precipitates, quenching signal In summary, overcome restriction enzymatic BCP requiring improved stability accuracy analysis, also broadened range coreactant-free perovskite-type biosensors.

Язык: Английский

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Gold and silver nanoparticles as tools to combat multidrug-resistant pathogens

Current Opinion in Colloid & Interface Science, Год журнала: 2023, Номер 66, С. 101710 - 101710

Опубликована: Май 29, 2023

The sudden emergence and rapid spreading of viral, bacterial, fungal infections the usual development resistance against traditional molecular drugs prompt urgent need for alternative approaches to kill or inactivate pathogenic agents. This motivation has inspired a vast number research works devoted design, synthesis, application nanomaterials, specifically inorganic plasmonic nanoparticles, as antimicrobial We will pay special attention articles from 2019 2023 where control colloidal properties, i.e., size, morphology, stability, are properly considered. Here we discuss latest advancement in characterization, activity Au Ag well hybrid systems based on combining metallic NPs with organic materials. also consider contributions focusing green synthesis particles, highlighting opportunities better predictivity functional properties.

Язык: Английский

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Copper-based nanomaterials for the treatment of bacteria-infected wounds: material classification, strategies and mechanisms

Coordination Chemistry Reviews, Год журнала: 2024, Номер 522, С. 216205 - 216205

Опубликована: Сен. 11, 2024

Язык: Английский

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Expanding Our Horizons: AIE Materials in Bacterial Research

Advanced Materials, Год журнала: 2024, Номер unknown

Опубликована: Сен. 9, 2024

Abstract Bacteria share a longstanding and complex relationship with humans, playing role in protecting gut health sustaining the ecosystem to cause infectious diseases antibiotic resistance. Luminogenic materials that aggregation‐induced emission (AIE) characteristics have emerged as versatile toolbox for bacterial studies through fluorescence visualization. Numerous research efforts highlight superiority of AIE this field. Recent advances are categorized into four areas: understanding interactions, antibacterial strategies, diverse applications, synergistic applications bacteria. Initial focuses on visualizing unseen bacteria progresses developing strategies involving electrostatic amphiphilic luminogens (AIEgens), various enhance affinity. progress includes using photodynamic photothermal therapies, toxicity studies, combined therapies. Diverse from environmental disinfection disease treatment, utilizing coatings, sensors, wound healing materials, etc., also provided. Finally, combining achieve enhanced outcomes explored. This review summarizes developmental trend is expected provide future directions advancing methodologies.

Язык: Английский

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3D printing technology and its revolutionary role in stent implementation in cardiovascular disease

Current Problems in Cardiology, Год журнала: 2024, Номер 49(6), С. 102568 - 102568

Опубликована: Апрель 8, 2024

Язык: Английский

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Bacterial elimination via cell membrane penetration by violet phosphorene peripheral sub-nanoneedles combined with oxidative stress

Chemical Science, Год журнала: 2024, Номер 15(13), С. 4926 - 4937

Опубликована: Янв. 1, 2024

The antibacterial performance and mechanism of antimicrobials depend on their structure. We propose bacterial eradication via cell membrane penetration induced by violet phosphorene peripheral sub-nanoneedles combined with oxidative stress.

Язык: Английский

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Probing capping mechanisms and polymer matrix loading of biogenic vaterite CaCO₃–Ag hybrid through X-ray photoelectron spectroscopy (XPS)

RSC Advances, Год журнала: 2024, Номер 14(21), С. 14624 - 14639

Опубликована: Янв. 1, 2024

XPS revealed Ag + and 0 in biogenic vaterite CaCO 3 –Ag microspheres. CMC PSS capping agents influenced species distribution. Polymorph transformations vaterite's stability were highlighted.

Язык: Английский

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