Paintable, Fast Gelation, Highly Adhesive Hydrogels for High‐fidelity Electrophysiological Monitoring Wirelessly DOI

Leqi Li,

Xinyuan Ye,

Zichong Ji

и другие.

Small, Год журнала: 2024, Номер unknown

Опубликована: Окт. 25, 2024

High-fidelity wireless electrophysiological monitoring is essential for ambulatory healthcare applications. Soft solid-like hydrogels have received significant attention as epidermal electrodes because of their tissue-like mechanical properties and high biocompatibility. However, it challenging to develop a hydrogel electrode that provides robust contact adhesiveness with glabrous skin hairy scalp high-fidelity, continuous signal detection. Here, paintable, fast gelation, highly adhesive, conductive engineered high-fidelity monitoring. The hydrogel, consisting gelatin, gallic acid, sodium citrate, lithium chloride, glycerol, Tris-HCl buffer solution exhibits reversible thermal phase transition capability, which endows the attributes on-skin applicability in situ gelation 15 s, thereby addressing aforementioned limitations. introduction acid enhances adhesive facilitating secure attachment or scalp. To accentuate potential applications at-home health monitoring, are demonstrated electrocardiogram recording one hour during various daily activities, well simultaneous electroencephalogram 30 min nap.

Язык: Английский

Self-powered hydrogel wearable bioelectronics DOI Creative Commons
Ruosi Chen, Mingyuan Gao, Dewei Chu

и другие.

Nano Energy, Год журнала: 2024, Номер 128, С. 109960 - 109960

Опубликована: Июль 3, 2024

The current wearable devices are largely rigid and bulky, which calls for the development of next-generation soft biocompatible technologies. Another limitation is that conventional generally powered by thick non-compliant batteries, hindering miniaturization improvement electronics. Hydrogels have attracted tremendous attention in field bioelectronics due to their tissue-like properties, can minimize mechanical mismatch between flexible biological tissues. Moreover, take advantage physical chemical energy from human body or ambient environment, such as motions, heat energy, biofuel, water wind power nature, more novel technology portable supply has been carried out, facilitating bioelectronics. In this review, recent advances self-powered based on hydrogels summarized. Firstly, excellent properties introduced, including prominent self-healing high conductivity incorporation conductive polymers additives, interfacial adhesion functionality, biocompatibility, antibacterial properties. Then, several strategies harvesting discussed, triboelectric nanogenerators (TENGs), piezoelectric (PENGs), thermoelectric (TEGs), biofuel cells (BFCs), hydrovoltaics, antennas, hydrogel-based batteries. Next, some representative applications illustrated (i.e., motion monitoring, healthcare monitoring therapies, neural stimulation human-machine interaction). Finally, a brief summary outlook hydrogel presented.

Язык: Английский

Процитировано

9

Beyond External Light: On-Spot Light Generation or Light Delivery for Highly Penetrated Photodynamic Therapy DOI
Xiao Cui, Xiang Li, Peng Cheng

и другие.

ACS Nano, Год журнала: 2023, Номер 17(21), С. 20776 - 20803

Опубликована: Окт. 24, 2023

External light sources, such as lasers, emitting diodes (LEDs) and lamps, are widely applied in photodynamic therapy (PDT); however, their use is severely limited by the nature of shallow tissue penetration depth. The recent exploration delivery or local generation on tumor sites has attracted much attention, owing to fact that these systems significantly endowed with high penetration. In this review, we briefly introduced principle "on-spot systems" PDT. These divided into different categories: (1) implantable luminescence, (2) mechanoluminescence, (3) electrochemiluminescence, (4) Cerenkov (5) chemiluminescence, (6) bioluminescence. Finally, applications, advantages, disadvantages PDT will be appropriately summarized further discussed detail. We believe review provide general guidance for design clinical studies PDT-mediated cancer treatments unparalleled merits.

Язык: Английский

Процитировано

19

Advances in wearable and implantable bioelectronics for precision medicine DOI
Kaichen Xu, Seung Hwan Ko, Jun Chen

и другие.

Bio-Design and Manufacturing, Год журнала: 2024, Номер 7(4), С. 383 - 387

Опубликована: Июль 1, 2024

Язык: Английский

Процитировано

6

Highly elastic, permeable liquid metal–iron fibre mat conductor for electrophysiological monitoring DOI Creative Commons
Jiawei Yang, Qing‐Yuan Sun, Zonglei Wang

и другие.

Wearable electronics., Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0

Progress in the Development of Flexible Devices Utilizing Protein Nanomaterials DOI Creative Commons
Chunhong Zhang, Chenxi Zhang, Yongchun Liu

и другие.

Nanomaterials, Год журнала: 2025, Номер 15(5), С. 367 - 367

Опубликована: Фев. 27, 2025

Flexible devices are soft, lightweight, and portable, making them suitable for large-area applications. These features significantly expand the scope of electronic demonstrate their unique value in various fields, including smart wearable devices, medical health monitoring, human-computer interaction, brain-computer interfaces. Protein materials, due to molecular structure, biological properties, sustainability, self-assembly ability, good biocompatibility, can be applied enhance sensitivity, stability, mechanical strength, energy density, conductivity devices. Protein-based flexible have become an important research direction fields bioelectronics wearables, providing new material support development more environmentally friendly reliable electronics. Currently, many proteins, such as silk fibroin, collagen, ferritin, so on, been used biosensors, memristors, storage power generation Therefore, this paper, we provide overview related field protein-based concept characteristics fabrication processes, characterization, evaluation, point out future

Язык: Английский

Процитировано

0

Wearable Healthcare Monitoring and Therapeutic Bioelectronics DOI Creative Commons
Ya Zhang, Haotian Chen, Yu Song

и другие.

Wearable electronics., Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0

Bioinspired Intelligent Electronic Skin for Medicine and Healthcare DOI Open Access
Zhirong Liu,

Junhao Hu,

Guozhen Shen

и другие.

Small Methods, Год журнала: 2025, Номер unknown

Опубликована: Фев. 5, 2025

Abstract Intelligent electronic skin aims to mimic, enhance, and even surpass the functions of biological skin, enabling artificial systems sense environmental stimuli interact more naturally with humans. In healthcare, intelligent is revolutionizing diagnostics personalized medicine by detecting early signs diseases programming exogenous for timely intervention on‐demand treatment. This review discusses latest progress in bioinspired its application healthcare. First, strategies development simulate or human are discussed, focusing on basic characteristics, as well sensing regulating functions. Then, applications health monitoring wearable therapies illustrating potential provide warning Finally, significance bridging gap between emphasized challenges future perspectives summarized.

Язык: Английский

Процитировано

0

Polydopamine Assisted Electroless Deposition of Strongly Adhesive NiFe Films for Flexible Spintronics DOI
Akhil K. Ramesh, Xingyu Chen, Ian P. Seetoh

и другие.

ACS Applied Materials & Interfaces, Год журнала: 2025, Номер unknown

Опубликована: Фев. 13, 2025

Cost-effective techniques for depositing durable magnetic thin films are essential realizing flexible spintronic devices in wearable and soft robotics applications. Here, we introduce a highly scalable electroless deposition technique coating ferromagnetic Ni80Fe20 onto polyimide polyethylene terephthalate substrates via polydopamine intermediate layer. The resultant demonstrated very good adhesion strength, especially those on substrates, which attained the highest ASTM 3359 rating of 5B exhibited tensile pull-off strength greater than 5.82 MPa (ASTM D4541). With assistance XPS TEM results, this unusual adhesive NiFe polymers can be traced to formation primary bonds across entire coating: (i) covalent bonding between polymer substrate polydopamine, (ii) coordinate catechol groups palladium ions, (iii) metallic NiFe. By annealing NiFe-on-polyimide samples at 300 °C-400 °C, crystallinity material was found improve, increased saturation magnetization 1350 emu/cm3 decreased coercivity 20 Oe. Ferromagnetic resonance also showed ∼31% improvement film's Gilbert damping constant after °C. Application bending strain squareness ratio by 22% but annealed film 18%. These results suggest that were sufficient quality devices, although their properties could improved if surface roughness physically deposited films.

Язык: Английский

Процитировано

0

Dynamic Electronic Structure Fluctuations in the De Novo Peptide ACC-Dimer Revealed by First-Principles Theory and Machine Learning DOI Creative Commons
Peter Mastracco, Luke N. Mohanam, Giacomo Nagaro

и другие.

Journal of Chemical Information and Modeling, Год журнала: 2025, Номер unknown

Опубликована: Фев. 14, 2025

Recent studies have reported long-range charge transport in peptide- and protein-based fibers wires, rendering this class of materials as promising charge-conducting interfaces between biological systems electronic devices. In the complex molecular environment biomolecular building blocks, however, it is unclear which chemical structural dynamic features support conductivity. Here, we investigate role finite temperature fluctuations on structure its implications for conductivity a peptide-based fiber material composed an antiparallel coiled coil hexamer, ACC-Hex, block. All-atom classical dynamics (MD) first-principles density functional theory (DFT) are combined with interpretable machine learning (ML) to understand relationship physical peptide dimer subunit ACC-Hex. For 1101 unique MD "snapshots" ACC dimer, hybrid DFT calculations predict significant variation near-gap orbital energies among snapshots, increase predicted number nearly degenerate states near highest occupied (HOMO), suggests improved Interpretable ML then used nuclear conformations states. We find that conformation descriptors interphenylalanine distance orientation are, expected, highly correlated increased state HOMO. Unexpectedly, also tightly backbones, well those describing change electrostatic around important predicting hole-accessible Our study illustrates utility tool understanding trends large-scale ab initio simulations.

Язык: Английский

Процитировано

0

Novel Electroactive Therapeutic Platforms for Cardiac Arrhythmia Management DOI Creative Commons
J. C. Yang, Longfei Li, Yiran Hu

и другие.

Advanced Science, Год журнала: 2025, Номер unknown

Опубликована: Фев. 14, 2025

Abstract Electroactive platforms have gained significant attention for their ability to convert various types of energy into electrical signals, offering promising applications in diverse biomedical fields. In cardiovascular care, these are increasingly valued innovative solutions managing cardiac functions and disorders. By regulating activity the heart, electroactive offer novel methods abnormal heart rhythms. This review explores latest advancements systems, categorizing them based on sources mechanisms, such as self‐powered conductive systems. It also highlights arrhythmia management, including monitoring, intervention, pacing, repairing. Finally, challenges, limitations, future opportunities clinical translation technologies discussed.

Язык: Английский

Процитировано

0