Nanoscale, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
Biological nanoparticles, particularly rod-shaped plant viruses, have emerged as promising candidates for various biomedical applications. This review focuses on the morphological characteristics and modification strategies of viruses such tobacco mosaic virus, potato virus X, papaya virus. These offer versatile approaches, including chemical, genetic, bio-modifications, well aspect ratio regulation. Their applications in drug delivery, antibacterial treatments, RNA bioimaging, immune modulation are extensively discussed. Rod-shaped exhibit unique advantages, uniformity size molecular weight, excellent biocompatibility, diverse modifiability inherent immunogenicity, making them highly suitable However, challenges remain their clinical translation. aims to provide insights into potential biological nanoparticles stimulate further research field virus-based biomaterials, which may lead innovative solutions immune-related therapies vaccine development.
Язык: Английский