A Review on Fluorescent Molecular Probes for Hg²⁺ Ion Detection: Mechanisms, Strategies, and Future Directions

ChemistrySelect, Год журнала: 2025, Номер 10(7)

Опубликована: Фев. 1, 2025

Abstract Fluorescent molecular probes have gained significant attention due to their exceptional attributes, such as enhanced specificity, sensitivity, and reversibility. This review explores how organic probe molecules' fluorescence properties change when metal ions like Hg 2+ bind the receptors. The alteration in results from distinct photophysical mechanisms photoinduced electron transfer, proton energy charge excimer formation, aggregation‐induced emission, C═N isomerization etc. Besides, induce chemical reactions resulting changes structural conformation properties. As a result, this effect specifically affects signal of molecules, which is beneficial for advancing sensor technology developed detect contamination. Focusing on environmental pollution biological sample analysis, study highlights applying fluorescent techniques using chromophores heavy ions, particularly ions. Thus, dyes with modifiable functional groups ensure precise detection offering robust platform monitoring public health safety. We examine capacities, sensing mechanisms, limits, strategies, methodologies utilized. article provides insights into efficacy progress domain sensors detecting

Язык: Английский

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Dual-Mode Multiple Ion Sensing via Analyte-Specific Modulation of Keto–Enol Tautomerization of an ESIPT Active Pyrene Derivative: Experimental Findings and Computational Rationalization

ACS Omega, Год журнала: 2023, Номер 8(7), С. 6349 - 6360

Опубликована: Фев. 13, 2023

A pyrene-based excited-state intramolecular proton transfer (ESIPT) active probe PMHMP was synthesized, characterized, and employed for the ppb-level, dual-mode, high-fidelity detection of Cu2+ (LOD: 7.8 ppb) Zn2+ ions 4.2 in acetonitrile medium. The colorless solution turned yellow upon addition Cu2+, suggesting its ratiometric, naked-eye sensing. On contrary, displayed concentration-dependent fluorescence rise till a 0.5 mole fraction subsequent quenching. Mechanistic investigations indicated formation 1:2 exciplex (Zn2+:PMHMP) at lower concentration Zn2+, which eventually into more stable 1:1 complex with an additional amount ions. However, both cases, it observed that hydroxyl group nitrogen atom azomethine unit were involved metal ion coordination, altered ESIPT emission. Furthermore, green-fluorescent 2:1 PMHMP-Zn2+ developed additionally fluorimetric analysis H2PO4- ion, owing to higher binding affinity PMHMP, could replace from preformed complex. other hand, formed tertiary adduct Zn2+-complex, leading distinguishable optical signal. extensive organized density functional theory calculations performed explore behavior geometrical electronic properties complexes.

Язык: Английский

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Fluorescence chemosensor for anion recognition, solvatochromism and protein binding studies based on Schiff- base derivative

Journal of Molecular Structure, Год журнала: 2024, Номер 1312, С. 138542 - 138542

Опубликована: Май 6, 2024

Язык: Английский

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Multifunctional Chemosensors for the Simultaneous Detection of Copper and Mercury Ions: Applications in Test Strip Fabrication, Spiking Studies, and Logic Gate Formulation

ACS Omega, Год журнала: 2025, Номер 10(9), С. 9527 - 9536

Опубликована: Фев. 25, 2025

This study reports the successful synthesis of three new benzidine-based chemosensors (CRBD-1, CRBD-2, and CRBD-3). Among these, CRBD-1 CRBD-2 exhibited exceptional selectivity ultrafast response toward Cu2+ Hg2+ ions, evident by a distinct naked-eye color change. The sensors demonstrated remarkable stability across broad pH range achieved low detection limits in ppm range. displayed high binding constant for (2.42 × 108) (1.45 107). Notably, limit (LOD) (0.953 ppm) (0.003 was significantly lower than established safety thresholds set WHO ESEPA. mechanism sensing, involving intramolecular charge transfer (ICT), thoroughly validated using UV–vis spectroscopy, 1H NMR, cyclic voltammetry, DFT, Job's plot analysis. Furthermore, reversibility studies enabled development logic gate operations potential future applications. functionality successfully evaluated real-world samples like vegetable juice water, as well test strips convenient, rapid, qualitative, quantitative, colorimetric aqueous environments.

Язык: Английский

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A chemosensing approach for the colorimetric and spectroscopic detection of Cr3+, Cu2+, Fe3+, and Gd3+ metal ions

The Science of The Total Environment, Год журнала: 2022, Номер 845, С. 157242 - 157242

Опубликована: Июль 9, 2022

Язык: Английский

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A highly selective Schiff base fluorescent sensor for Zn2+, Cd2+ and Hg2+ based on 2,4-dinitrophenylhydrazine derivative

Inorganic Chemistry Communications, Год журнала: 2023, Номер 154, С. 110959 - 110959

Опубликована: Июнь 26, 2023

Язык: Английский

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Highly sensitive and selective Schiff base chemosensor for Cu2+ and 2,4-D detection: A promising analytical approach

Microchemical Journal, Год журнала: 2023, Номер 197, С. 109817 - 109817

Опубликована: Дек. 19, 2023

Язык: Английский

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A Simple and Rapid Quinoline Schiff Base as a Fluorescent Probe for Zn²⁺ and Its Application in Test Strips

ChemistrySelect, Год журнала: 2024, Номер 9(9)

Опубликована: Март 1, 2024

Abstract A simple fluorescent probe, ( E )‐ N ‐(3‐methoxy‐4‐methylphenyl)‐1‐(quinolin‐2‐yl)methanimine L ), was synthesized via Schiff base condensation reaction between quinoline‐2‐carboxaldehyde and 3‐methoxy‐4‐methylaniline. can be used as a ′turn‐on′ probe for the selective sensitive detection of Zn 2+ ions in CH 3 OH/HEPES medium. The limit 1.04×10 −7 M. Job plot analysis shows that binding stoichiometry is 1 : 1, further verified by single crystal structure. fluorescence‐enhanced response towards may related to chelation‐enhanced fluorescence (CHEF) supported theoretical calculations. By adding EDTA, reversibility demonstrated, enabling construction functional molecular logic circuit. In addition, successfully incorporated into test strips quantitative .

Язык: Английский

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A Spectroscopic Reassessment of 2,6‐Diformyl‐4‐methyl Phenol and its Use as a Fluorescent Probe in Solution and Solid Phases

ChemistrySelect, Год журнала: 2025, Номер 10(3)

Опубликована: Янв. 1, 2025

Abstract 4‐methyl 2,6‐diformyl phenol ( DFP ) is widely used for constructing metal complexes as well an array of chemosensors. However, the detailed photophysical understanding in various media and states aggregation has not been explored. shows excellent dependence on solvent polarity to furnish varyingly emitting species, which were studied by steady state time resolved emission spectroscopy. In lower solvents from keto form, whereas polar aprotic protic a cumulative contribution locally excited enol anion form. solid state, was due presence aggregated forms undergoing ESIPT make it yellow emitter. could act ratiometric sensor detecting water THF ACN (LOD∼ 0.4%). neat water, detect Zn 2+ upto 7.05 × 10 −7 (M) change maximum green blue. coated filter papers utilized reversible optical ammonia vapor using UV light smartphone‐based application. The sensing materialized ease loss polar/protic medium NH 3 .

Язык: Английский

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Schiff Bases and Their Metal Complexes: Synthesis, Structural Characteristics and Applications

IntechOpen eBooks, Год журнала: 2023, Номер unknown

Опубликована: Март 2, 2023

The development of Schiff base was a major step forward in the area coordination chemistry. bases, class organic compounds, carry imine or azomethine (>C=N–) functional group. bases played an influencing role chemistry and were key point inorganic, bioinorganic optical materials. widely used organic, analytical chemistry, account for significant portion more commonly employed classes molecules. ability ligands to form stable metal complexes with wide range transition other ions makes them extremely useful. Condensation primary amine aldehyde ketone yields bases. In this chapter, we focused on introducing classified their complexes, discussed several synthesis methods, including conventional green approaches. This chapter also elaborated industries’ applications, such as food industry, agrochemical dye catalysis, energy storage, environmental, chemo-sensing, bio-sensing, biomedical applications novel complexes.

Язык: Английский

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