Protoporphyrin IX-modified chitosan/sodium alginate based cryogels for rapid hemostasis and antibacterial photodynamic therapy of infected wound healing

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 303, С. 140614 - 140614

Опубликована: Фев. 2, 2025

Язык: Английский

Electrospun Nanofiber Platforms for Photodynamic Therapy: Role and Efficacy in Cancer, Antimicrobial, and Wound Healing Applications

Macromolecular Materials and Engineering, Год журнала: 2025, Номер unknown

Опубликована: Фев. 14, 2025

Abstract Electrospinning offers a versatile platform for developing nanofibrous scaffolds capable of enhancing the therapeutic potential photodynamic therapy (PDT). Photosensitizer (PS) loaded fibers exhibit high surface area‐to‐volume ratio, promoting efficient drug delivery, prolonged retention at target site, and controlled release profiles. Inducing reactive oxygen species (ROS) generation through light activation targeted approach, selectively generating cytotoxic effects in cancerous or pathogenic cells while minimizing damage to healthy tissue. This selective cytotoxicity arises because ROS are produced only illuminated areas where PS releases accumulates, limiting their harmful desired regions. Additionally, PS‐loaded highly effective wound healing applications, cell proliferation tissue regeneration providing barrier against microbial infections. review highlights recent advances design biomedical application nanofibers, emphasizing influence on viability effectiveness inhibition, thereby setting stage future innovations cancer therapy, healing, infection control.

Язык: Английский

Visible light-trigged photodynamic antibacterial film with mild temperature enhancement for long-term preservation of perishable products

Chemical Engineering Journal, Год журнала: 2024, Номер 503, С. 158457 - 158457

Опубликована: Дек. 9, 2024

Язык: Английский