Emerging Rapid Detection Methods for the Monitoring of Cardiovascular Diseases: Current Trends and Future Perspectives

Materials Today Bio, Год журнала: 2025, Номер 32, С. 101663 - 101663

Опубликована: Март 14, 2025

Язык: Английский

Cardiac Troponin I Biosensors: Innovations in Real‐Time Diagnosis of Cardiovascular Diseases

Analytical Science Advances, Год журнала: 2025, Номер 6(1)

Опубликована: Апрель 1, 2025

ABSTRACT Cardiac troponin I (cTnI) is a crucial biological macromolecule found in the contractile apparatus of cardiac myocytes, exclusively expressed cardiomyocytes. It released into bloodstream upon tissue injury, serving as vital biomarker for early detection various heart diseases. Despite advancements cTnI diagnostics and cardiovascular disease (CVD) detection, there an ongoing need more effective diagnostic methods innovative approaches. Current CVD diagnosis often relies on clinical signs symptoms, supplemented by molecular imaging (MI) or biomarkers associated with CVD. However, challenges remain regarding reliability, specificity accuracy analyses myocardial infarction, particularly its stages. Emerging nanomaterial systems present promising solutions enhancing tools due to their unique physical chemical properties. Various nanomaterials, such gold nanoparticles, carbon nanotubes, quantum dots, lipids polymer are paving new pathways detection. The science offer exciting opportunities screening. This article provides comprehensive overview these advancements, categorizing research efforts focused both optical electrochemical platforms, thereby contributing evolution screening methodologies addressing critical reliable solutions.

Язык: Английский

Electrochemiluminescence Lateral Flow Immunosensor Using Luminol-Labeled Silver Nanoparticles for Highly Sensitive and Quan-titative Detection of Cardiac Troponin I

Talanta, Год журнала: 2025, Номер unknown, С. 128159 - 128159

Опубликована: Апрель 1, 2025

Язык: Английский