Materials Today Chemistry, Год журнала: 2022, Номер 26, С. 101155 - 101155
Опубликована: Сен. 30, 2022
Язык: Английский
ACS Nano, Год журнала: 2022, Номер 16(5), С. 7080 - 7115
Опубликована: Май 5, 2022
This paper provides an overview of recent developments in the field volatile organic compound (VOC) sensors, which are finding uses healthcare, safety, environmental monitoring, food and agriculture, oil industry, other fields. It starts by briefly explaining basics VOC sensing reviewing currently available quickly progressing approaches. then discusses main trends materials' design with special attention to nanostructuring nanohybridization. Emerging materials strategies highlighted their involvement different types technologies is discussed, including optical, electrical, gravimetric sensors. The review also detailed discussions about limitations offers potential solutions. status suggestions promising directions for future development summarized.
Язык: Английский
Процитировано
294
Analytical Chemistry, Год журнала: 2021, Номер 93(24), С. 8585 - 8594
Опубликована: Июнь 3, 2021
The global pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus has revealed urgent need for accurate, rapid, and affordable diagnostic tests epidemic understanding management monitoring population worldwide. Though current methods including real-time polymerase chain reaction (RT-PCR) provide sensitive detection of SARS-CoV-2, they require relatively long processing time, equipped laboratory facilities, highly skilled personnel. Laser-scribed graphene (LSG)-based biosensing platforms have gained enormous attention as miniaturized electrochemical systems, holding an potential point-of-care (POC) tools. We describe here a LSG-based sensing scheme disease 2019 (COVID-19) diagnosis combined with three-dimensional (3D) gold nanostructures. This electrode was modified SARS-CoV-2 spike protein antibody following proper surface modifications proved X-ray photoelectron spectroscopy (XPS) scanning electron microscopy (SEM) characterizations well techniques. system integrated into handheld POC operated using custom smartphone application, providing user-friendly platform due to its ease operation, accessibility, systematic data management. analytical features immunoassay were evaluated standard solution S-protein in range 5.0-500 ng/mL limit 2.9 ng/mL. A clinical study carried out on 23 patient blood serum samples successful COVID-19 diagnosis, compared commercial RT-PCR, test, enzyme-linked immunosorbent assay (ELISA) IgG IgA test results. Our provides faster results tools offers promising alternative next-generation applications.
Язык: Английский
Процитировано
153
Advanced Materials Technologies, Год журнала: 2021, Номер 7(1)
Опубликована: Сен. 3, 2021
Abstract Wearable sensors are emerging as a new technology to detect physiological and biochemical markers for remote health monitoring. By measuring vital signs such respiratory rate, body temperature, blood oxygen level, wearable offer tremendous potential the noninvasive early diagnosis of numerous diseases Covid‐19. Over past decade, significant progress has been made develop with high sensitivity, accuracy, flexibility, stretchability, bringing reality paradigm In this review paper, latest advances in sensor systems that can measure at an accuracy level matching those point‐of‐care tests presented. particular, focus is placed on behavior, which identified critical signals diagnosing monitoring Various designs based different materials working mechanisms summarized. This concluded by identifying remaining challenges future opportunities field.
Язык: Английский
Процитировано
110
Sensors, Год журнала: 2022, Номер 22(3), С. 1238 - 1238
Опубликована: Фев. 6, 2022
Early-stage disease diagnosis is of particular importance for effective patient identification as well their treatment. Lack compliance the existing diagnostic methods, however, limits prompt diagnosis, rendering development non-invasive tools mandatory. One most promising methods that has also attracted great research interest during last years breath analysis; method detects gas-analytes such exhaled volatile organic compounds (VOCs) and inorganic gases are considered to be important biomarkers various disease-types. The ability gas-pattern detection using analytical techniques especially sensors been widely discussed in literature; incorporation novel nanomaterials sensor-development proved enhance sensor performance, both selective cross-reactive applications. aim first part this review provide an up-to-date overview main categories studied applications via highlight role nanomaterials. second concentrates on remarkable applicability analysis differential phenotyping, staging several disease-types, which currently amongst pressing challenges field.
Язык: Английский
Процитировано
89
ACS Sensors, Год журнала: 2022, Номер 7(4), С. 912 - 913
Опубликована: Апрель 22, 2022
ADVERTISEMENT RETURN TO ISSUEEditorialNEXTThe Present and Future of Gas SensorsHee-Tae JungHee-Tae JungKorea Advanced Institute Science Technology, Daejeon 34141, Republic KoreaMore by Hee-Tae Junghttps://orcid.org/0000-0002-5727-6732Cite this: ACS Sens. 2022, 7, 4, 912–913Publication Date (Web):April 22, 2022Publication History Received1 April 2022Published online22 inissue 22 2022https://pubs.acs.org/doi/10.1021/acssensors.2c00688https://doi.org/10.1021/acssensors.2c00688editorialACS PublicationsCopyright © 2022 American Chemical Society. This publication is available under these Terms Use. Request reuse permissions free to access through this site. Learn MoreArticle Views7348Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum full text article downloads since November 2008 (both PDF HTML) across all institutions individuals. These metrics regularly updated reflect usage leading up last few days.Citations number other articles citing article, calculated Crossref daily. Find more information about citation counts.The Altmetric Attention Score a quantitative measure attention that research has received online. Clicking on donut icon will load page at altmetric.com with additional details score social media presence for given article. how calculated. Share Add toView InAdd Full Text ReferenceAdd Description ExportRISCitationCitation abstractCitation referencesMore Options onFacebookTwitterWechatLinked InRedditEmail (638 KB) Get e-AlertscloseSUBJECTS:Electrical conductivity,Materials,Oxides,Sensors,Two dimensional materials e-Alerts
Язык: Английский
Процитировано
79
Exploration, Год журнала: 2023, Номер 3(1)
Опубликована: Янв. 7, 2023
Coronavirus disease 2019 (COVID-19) pandemic has exemplified how viral growth and transmission are a significant threat to global biosecurity. The early detection treatment of infections is the top priority prevent fresh waves control pandemic. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) been identified through several conventional molecular methodologies that time-consuming require high-skill labor, apparatus, biochemical reagents but have low accuracy. These bottlenecks hamper methods from resolving COVID-19 emergency. However, interdisciplinary advances in nanomaterials biotechnology, such as nanomaterials-based biosensors, opened new avenues for rapid ultrasensitive pathogens field healthcare. Many updated namely electrochemical, field-effect transistor, plasmonic, colorimetric employ nucleic acid antigen-antibody interactions SARS-CoV-2 highly efficient, reliable, sensitive, manner. This systematic review summarizes mechanisms characteristics biosensors detection. Moreover, continuing challenges emerging trends biosensor development also discussed.
Язык: Английский
Процитировано
55
Advanced Science, Год журнала: 2024, Номер 11(19)
Опубликована: Март 13, 2024
Abstract Diabetic ketoacidosis (DKA) is a life‐threatening acute complication of diabetes characterized by the accumulation ketone bodies in blood. Breath acetone, ketone, directly correlates with blood ketones. Therefore, monitoring breath acetone can significantly enhance safety and efficacy care. In this work, design fabrication an InP/Pt/chitosan nanowire array‐based chemiresistive sensor reported. By incorporation chitosan as surface‐functional layer Pt Schottky contact for efficient charge transfer processes photovoltaic effect, self‐powered, highly selective sensing achieved. The has exhibited ultra‐wide detection range from sub‐ppb to >100 000 ppm level at room temperature, covering those exhaled healthy individuals (300–800 ppb) people high risk DKA (>75 ppm). also been successfully integrated into handheld testing prototype, Ketowhistle, which detect different ranges concentrations simulated samples. Ketowhistle demonstrates immediate potential non‐invasive living diabetes, particular prevention.
Язык: Английский
Процитировано
26
Small Science, Год журнала: 2025, Номер unknown
Опубликована: Янв. 15, 2025
Volatile organic compounds (VOCs) are a class of with high vapor pressure and low boiling points, widely present in both natural environments human activities. VOCs released from various sources not only contribute to environmental pollution but also pose threats ecosystems health. Moreover, some considered biomarkers exhaled breath can be utilized identify diseases. Therefore, monitoring controlling VOC emissions concentrations crucial for safeguarding the environment In recent years, significant advancements have been achieved micro‐electromechanical system (MEMS)‐based sensing optical technologies, offering new avenues detection. This article provides comprehensive overview research progress MEMS sensors, focusing on their mechanisms classifications. It then discusses role artificial intelligence enhancing identification quantification, as well trends toward sensor miniaturization intelligence. Furthermore, highlights diverse applications sensors medical diagnostics, agricultural food testing, Internet Things. Finally, it emphasizes opportunities challenges associated providing valuable insights practical applications.
Язык: Английский
Процитировано
3
Frontiers in Genetics, Год журнала: 2021, Номер 12
Опубликована: Июль 23, 2021
Coronavirus disease 2019 (COVID-19) pandemic triggered an unprecedented global effort in developing rapid and inexpensive diagnostic prognostic tools. Since the genome of SARS-CoV-2 was uncovered, detection viral RNA by RT-qPCR has played most significant role preventing spread virus through early tracing suspected COVID-19 cases screening at-risk population. However, a large number alternative test methods based on or proteins host factors associated with infection have been developed evaluated. The application metabolomics infectious diagnostics is evolving area science that boosted urgency pandemic. Metabolomics approaches rely analysis volatile organic compounds exhaled patients hold promise for applications large-scale population point-of-care (POC) setting. On other hand, successful mass-spectrometry to detect specific spectral signatures nasopharyngeal swab specimens may significantly save cost turnaround time testing microbiology virology laboratories. Active research also ongoing discovery potential metabolomics-based markers can be applied serum plasma specimens. Several metabolic pathways related amino acid, lipid energy metabolism were found affected severe COVID-19. In particular, tryptophan via kynurenine pathway persistently dysregulated several independent studies, suggesting roles metabolites this such as tryptophan, 3-hydroxykynurenine disease. standardization clinical validation are necessary before these tests With rapidly expanding data profiles varying degrees severity, it likely will play important near future predicting outcome greater degree certainty.
Язык: Английский
Процитировано
67
Molecules, Год журнала: 2021, Номер 26(18), С. 5514 - 5514
Опубликована: Сен. 11, 2021
The detection of chemical compounds in exhaled human breath presents an opportunity to determine physiological state, diagnose disease or assess environmental exposure. Recent advancements metabolomics research have led improved capabilities explore metabolic profiles breath. Despite some notable challenges sampling and analysis, represents a desirable medium for applications, foremost due its non-invasive, convenient practically limitless availability. Several breath-based tests that target either endogenous exogenous gas-phase are currently established practical and/or clinical use. This review outlines the concept analysis context these unique their applications. respective biomarkers targeted each test discussed relation production body development implementation associated tests. paper concludes with brief insight into prospective outlook future direction research.
Язык: Английский
Процитировано
57