2D Nanomaterials in Biosensing: Synthesis, Characterization, Integration in Biosensors and their Applications

Biosensors and Bioelectronics X, Год журнала: 2025, Номер unknown, С. 100615 - 100615

Опубликована: Март 1, 2025

Язык: Английский

Development of a Rapid-Response Fluorescent Probe for H2S: Mechanism Elucidation and Biological Applications

Biosensors, Год журнала: 2025, Номер 15(3), С. 174 - 174

Опубликована: Март 7, 2025

Hydrogen sulfide (H2S) is an important signaling molecule involved in various physiological and pathological processes, making its accurate detection biological systems highly desirable. In this study, two fluorescent probes (M1 M2) based on 1,8-naphthalimide were developed for H2S via a nucleophilic aromatic substitution. M1 demonstrated high sensitivity selectivity aqueous media, with limit of 0.64 µM strong linear fluorescence response the range 0–22 NaHS. The reaction kinetics revealed rapid response, rate constant 7.56 × 102 M−1 s−1, was most effective pH 6–10. Mechanism studies using 1H NMR titration confirmed formation 4-hydroxyphenyl-1,8-naphthalimide as product H2S-triggered applied MDA-MB-231 cells cell imaging, which provided significant enhancement upon NaHS treatment, confirming applicability detecting environments. comparison, M2, designed extended conjugation red-shifted emission, exhibited weaker due to reduced stability naphtholate lower solubility. These results demonstrate that selective probe H2S, providing valuable resource investigating roles health disease.

Язык: Английский

Advances in memristive gas sensors: a review

Talanta, Год журнала: 2025, Номер unknown, С. 128058 - 128058

Опубликована: Апрель 1, 2025

Язык: Английский