Photoinduced, additive- and photosensitizer-free multi-component synthesis of naphthoselenazol-2-amines with air in water

Green Chemistry, Год журнала: 2023, Номер 25(20), С. 7983 - 7987

Опубликована: Янв. 1, 2023

An atom- and step-economical, efficient eco-friendly method for constructing naphthoselenazol-2-amines through a visible-light photocatalytic multi-component reaction under aqueous phase conditions is reported.

Язык: Английский

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Visible-light-induced direct perfluoroalkylation/heteroarylation of [1.1.1]propellane to diverse bicyclo[1.1.1]pentanes (BCPs) under metal and photocatalyst-free conditions

Green Chemistry, Год журнала: 2023, Номер 25(3), С. 986 - 992

Опубликована: Янв. 1, 2023

This study describes a green and novel multi-component reaction for direct perfluoroalkylation/heteroarylation of [1.1.1]propellane with heteroarenes perfluoroalkyl iodines to diverse bicyclo[1.1.1]pentanes (BCPs).

Язык: Английский

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Photoinduced, metal- and photosensitizer-free decarboxylative C–H (amino)alkylation of heteroarenes in a sustainable solvent

Green Chemistry, Год журнала: 2023, Номер 25(5), С. 1975 - 1981

Опубликована: Янв. 1, 2023

This study describes a green and sustainable photoinduced strategy for decarboxylative C–H (amino)alkylation of heteroarenes with carboxylic acids under metal- photosensitizer-free conditions.

Язык: Английский

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Merging Photoinduced Electron Transfer with Hydrogen Atom Transfer: Formal β-C(sp³)–H Pyridination of Carbonyls

The Journal of Organic Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 9, 2025

In this study, a novel approach that combines photoinduced electron transfer (ET) with hydrogen atom (HAT) has been introduced for the selective β-C(sp3)–H pyridination of carbonyl compounds. This method is notable its absence transition metals and ability to function under benign reaction conditions, resulting in range pyridinated derivatives consistently moderate good yields. The significance technique further underscored by potential late-stage functionalization pharmaceutically significant molecules. Mechanistic investigations confirmed proceeds via radical-mediated pathway.

Язык: Английский

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Photoelectrochemical upcycling of PVC plastic waste for the synthesis of chlorinated quinolinone derivatives

Organic Chemistry Frontiers, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Herein, an environmentally friendly methodology has been established for the photoelectrochemical chlorination of C(sp 2 )–H bonds in quinolinone derivatives using PVC plastic waste as chlorine source.

Язык: Английский

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Three‐Component Reactions of Quinoxalin‐2(1H)‐ones: Recent Advances

European Journal of Organic Chemistry, Год журнала: 2023, Номер unknown

Опубликована: Сен. 11, 2023

Abstract The multicomponent reactions of quinoxalin‐2(1 H )‐ones has attracted considerable interest due to their significant biological and chemical activities. very recent advances (from 2021 the beginning 2023) on radical three‐component cascade reaction )‐one derivatives at C3 position were summarized in this mini‐review. According kind types involved, some representative examples detailed mechanism have been categorized discussed. red front was covered by Figure 1.

Язык: Английский

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α-Amino Radical-Mediated Difunctionalization of Alkenes with Polyhaloalkanes and N-Heteroarenes

Organic Letters, Год журнала: 2023, Номер 25(11), С. 1994 - 1998

Опубликована: Март 15, 2023

Herein, we report a mild and practical protocol for the α-perchloroalkyl β-heteroarylation of alkenes using available chloroform as dichloromethyl source via α-amino radical-mediated halogen-atom transfer. Various substrates are compatible under reaction conditions, providing corresponding products in moderate to good yields. This strategy gives an efficient convenient method introduction chloroalkyl motifs into N-heteroarenes. The control experiment demonstrates that radical generated situ is key intermediate transformation.

Язык: Английский

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Recent Developments in Direct C–H Functionalization of Quinoxalin-2(1H)-Ones via Multi-Component Tandem Reactions

Molecules, Год журнала: 2023, Номер 28(6), С. 2513 - 2513

Опубликована: Март 9, 2023

The direct C-H multifunctionalization of quinoxalin-2(1H)-ones via multicomponent reactions has attracted considerable interest due to their diverse biological activities and chemical profile. This review will focus on recent achievements. It mainly covers reaction methods for the simultaneous introduction C-C bonds C-RF/C/O/N/Cl/S/D into mechanisms. Meanwhile, future developments multi-component are envisaged, such as construction C-B/SI/P/F/I/SE through reactions; fused ring macrocyclic compounds; asymmetric synthesis; green chemistry; bionic structures other fields. aim is enrich at C3 position, which have rich applications in materials chemistry pharmaceutical pharmacology.

Язык: Английский

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Photo‐Triggered Self‐Induced Homolytic Dechlorinative Sulfonylation/Cyclization of Unactivated Alkenes: Synthesis of Quinazolinones Containing a Sulfonyl Group

Advanced Synthesis & Catalysis, Год журнала: 2021, Номер 364(4), С. 766 - 772

Опубликована: Ноя. 24, 2021

Abstract A self‐photocatalyzed sulfonylation/cyclization of quinazolinones containing unactivated alkenes with various sulfonyl chlorides was developed. The protocol provides access to radicals via energy transfer from the quinazolinone skeleton chloride. Notably, transformations proceeded without any external photocatalysts, additives, or oxidants, providing an alternative method for fabricating sulfonylated compounds. magnified image

Язык: Английский

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Decatungstate-photocatalyzed direct coupling of inert alkanes and quinoxalin-2(1H)-ones with H₂ evolution

Organic Chemistry Frontiers, Год журнала: 2022, Номер 9(10), С. 2728 - 2733

Опубликована: Янв. 1, 2022

A tetrabutylammonium decatungstate (TBADT)-photocatalyzed direct coupling of inert alkanes and quinoxalin-2(1 H )-ones with 2 evolution was developed at room temperature.

Язык: Английский

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