Chemical Communications,
Год журнала:
2024,
Номер
unknown
Опубликована: Янв. 1, 2024
Herein,
we
unveil
a
method
for
synthesizing
substituted
pyrrole
and
pyrazine
compounds
via
double
dehydrogenative
coupling
of
amino
alcohols
with
primary
alcohols,
facilitated
by
Mn(
i
)–PNP
catalysis,
which
uniquely
enables
the
simultaneous
formation
C–C
C–N
bonds.
Catalysis Science & Technology,
Год журнала:
2023,
Номер
13(19), С. 5745 - 5756
Опубликована: Янв. 1, 2023
We
report
manganese-catalyzed
CH
alkylation
of
indole/indolines
with
alcohols,
where
catalyst
control
provides
product
selectivity.
synthesise
several
life
science
molecules
(vibrindole
A,
turbomycin
B
alkaloid
and
antileukemic
anticancer
agents).
Advanced Synthesis & Catalysis,
Год журнала:
2023,
Номер
365(24), С. 4458 - 4494
Опубликована: Ноя. 24, 2023
Abstract
The
preservation
of
scarce
rare
earth
metals,
such
as
palladium,
rhodium,
iridium,
and
others,
poses
a
significant
challenge
for
humanity
due
to
their
limited
availability.
These
metals
might
be
replaced
by
earth‐abundant
3d‐transition
cobalt,
manganese,
iron,
nickel,
copper,
etc
.
Isoquinolines
have
acquired
an
important
position
in
synthetic
organic
chemistry
well
medicinal
chemistry.
They
manifest
diverse
range
natural
molecules,
serving
pivotal
synthons
the
synthesis
numerous
bioactive
compounds
with
notable
significance.
Numerous
reports
on
isoquinoline
derivatives
via
transition
metal
catalysis
been
published
worldwide.
In
this
review,
we
summarize
recent
approaches
synthesizing
various
using
3d‐transition‐metal
catalysts
since
2020.
review
has
divided
into
different
3d‐transition‐metal‐based
catalysis.
We
expect
that
will
bring
better
overview
present
status
progress
made
isoquinolines
persuade
more
advancements
research
area
near
future.
Catalysis Science & Technology,
Год журнала:
2024,
Номер
14(15), С. 4366 - 4375
Опубликована: Янв. 1, 2024
Herein,
an
efficient
and
environmentally
friendly
Cu-BTC
catalytic
system
is
reported,
which
can
be
successfully
applied
to
the
oxidative
coupling
of
benzyl
alcohols
for
construction
C–X
(X
=
N,
O)
bonds.
Catalysis Science & Technology,
Год журнала:
2024,
Номер
14(20), С. 5959 - 5969
Опубликована: Янв. 1, 2024
This
manuscript
describes
the
synthesis
of
triazolyl-pyridine-based
pincer
cationic
and
neutral
nickel
complexes
their
application
in
microwave-assisted
quinolines.
Chemical Communications,
Год журнала:
2023,
Номер
59(60), С. 9267 - 9270
Опубликована: Янв. 1, 2023
Herein,
we
describe
acridine-based
SNS-Ru
pincer-catalysed
unprecedented
dehydrogenative
annulation
of
alcohols
with
2'-aminoacetophenone
to
synthesize
2,3-disubstituted-4-quinolones.
The
developed
protocol
was
utilized
a
wide
range
various
aminoacetophenones.
To
expand
the
synthetic
utility,
4-quinolones
antibiotic
properties
were
synthesized
and
important
post-synthetic
modifications
scaffolds
performed.
Various
control
experiments
performed
understand
mechanism,
which
showed
that
C-alkylation
has
edge
over
N-alkylation
referred
possibility
in
situ
alkenylation
branched
ketones.
PtS/ZnIn2S4
nanocomposites
are
obtained
via
a
microwave-assisted
synthesis
followed
by
photoreduction.
The
resultant
used
as
an
effective
multifunctional
photocatalyst
for
the
reaction
between
alcohols
and
o-aminobenzamide
to
coproduce
quinazolinones
hydrogen
under
visible
light,
cascade
alcohols/aldehydes
transformation,
condensation
aldehydes
o-aminobenzamide,
well
dehydrogenation/cyclization
produce
quinazolinones.
PtS
acts
efficient
cocatalyst
promote
dehydrogenation
of
both
intermediates
production
An
almost
complete
conversion
was
achieved
in
24
h,
with
yield
98.8%
2-phenyl-quinazline-4(3H)-one
quantitative
produced
over
after
irradiated
h.
apparent
quantum
at
450
nm
is
determined
15.2%.
superior
activity
observed
nanocomposite
compared
that
either
NiS/ZnIn2S4
or
MoS2/ZnIn2S4
can
be
ascribed
moderate
binding
surface
adsorbed
H*.
This
study
supplies
effective,
green,
atom-economic
strategy
coproduction
light.
work
also
demonstrates
high
potential
fabrication
metal
sulfide-based
catalysts
light-driven
one-pot
tandem/cascade
reactions.
Dalton Transactions,
Год журнала:
2024,
Номер
53(12), С. 5580 - 5591
Опубликована: Янв. 1, 2024
This
manuscript
describes
the
synthesis
and
Mn
I
complexes
of
triazolyl-pyridine-based
phosphine
ligand
their
catalytic
utility
in
quinoline
derivatives
transfer
hydrogenation
aldehydes
ketones.
Chemistry - A European Journal,
Год журнала:
2023,
Номер
29(61)
Опубликована: Июль 24, 2023
Abstract
Sustainable
chemical
production
requires
fundamentally
new
types
of
catalysts
and
catalytic
technologies.
The
development
coherent
robust
systems
based
on
earth‐abundant
transition
metals
is
essential,
but
highly
challenging.
Herein,
we
systematically
explored
a
general
hydrogenative
cleavage/N‐alkylation
tandem
cyclic
acyclic
diazo
(N=N)
compounds
to
value‐added
amines
under
manganese
catalysis.
reaction
catalyzed
by
single‐site
molecular
complex
proceeds
via
dehydrogenation,
transfer
hydrogenation,
borrowing
hydrogenation
strategies.
Interestingly,
the
involves
abundantly
available
renewable
feedstocks,
such
as
alcohols,
that
can
act
(transfer)hydrogenating
alkylating
agents.
synthetic
application
our
approach
in
large‐scale
pharmaceutical
synthesis
easy
access
demanding
N
‐CH
3
/CD
derivatives
are
also
demonstrated.
Kinetic
studies
show
rate
depends
concentration
alcohol
Mn‐catalyst
follows
fractional
orders.
Several
selective
bond
activation/formation
reactions
occur
sequentially
amine–amide
metal‐ligand
cooperation.
Abstract
Catalytic
hydrogenation/dehydrogenation
reactions
are
one
of
the
most
active
areas
research
for
synthesis
pharmaceuticals
and
fine
chemicals.
Despite
several
efficient
homogeneous
catalysts
that
have
already
been
identified,
highly
heterogeneous
remain
elusive.
Herein,
we
report
an
easy
convenient
wet
impregnation
method
Pd‐nanoclusters
supported
on
ZnO
nanoparticles.
The
catalyst
displays
a
multifunctional
role
in
2‐aryl
quinolines
using
alcohol
2‐nitrobenzyl
as
reactants
via
dehydrogenation/hydrogenation
pathway
under
neat
base‐free
reaction
conditions.
exhibits
excellent
selectivity
can
be
recycled
five
times
without
appreciable
loss
its
activity.
Chemistry - An Asian Journal,
Год журнала:
2022,
Номер
17(23)
Опубликована: Сен. 19, 2022
A
water-soluble
bifunctional,
bistate
ruthenium
catalyst
has
been
developed
using
the
8-aminoquinoline
ligand
which
responds
to
an
acid-base
stimuli
and
is
catalytically
active
for
two
complementary
reactions.
The
"Ru-amino
state"
highly
catalytic
transfer
hydrogenation
of
various
aldehydes
formic
acid
as
hydrogen
source
resulting
in
a
range
primary
alcohols.
On
other
hand,
"Ru-amido
acceptorless
dehydrogenation
alcohols
yield
carboxylate
salts
or
ketones.
reactions
can
be
carried
out
air
without
inert
atmosphere
products
purified
by
simple
extraction
use
any
chromatographic
techniques.
functional
groups
include
electron-rich
deficient
(hetero)arenes
alkenes,
alkynes,
halides,
esters,
cyano,
nitro
groups,
are
all
well
tolerated,
indicating
excellent
chemoselectivity
hydrogenation.