Double dehydrogenative coupling of amino alcohols with primary alcohols under Mn(I) catalysis DOI Creative Commons
Ganesan Sivakumar,

Abhijith Karattil Suresh,

Smruti Padhy

и другие.

Chemical Communications, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Herein, we unveil a method for synthesizing substituted pyrrole and pyrazine compounds via double dehydrogenative coupling of amino alcohols with primary alcohols, facilitated by Mn( i )–PNP catalysis, which uniquely enables the simultaneous formation C–C C–N bonds.

Язык: Английский

Divergence in CH alkylation of indoles under Mn catalysis DOI Creative Commons
Akash Mondal, Rohit Kumar,

Abhijith Karattil Suresh

и другие.

Catalysis Science & Technology, Год журнала: 2023, Номер 13(19), С. 5745 - 5756

Опубликована: Янв. 1, 2023

We report manganese-catalyzed CH alkylation of indole/indolines with alcohols, where catalyst control provides product selectivity. synthesise several life science molecules (vibrindole A, turbomycin B alkaloid and antileukemic anticancer agents).

Язык: Английский

Процитировано

7

Recent Advances in the 3 d‐Transition‐Metal‐Catalyzed Synthesis of Isoquinolines and its Derivatives DOI
Vipin K. Maikhuri, Manish Rawat, Diwan S. Rawat

и другие.

Advanced Synthesis & Catalysis, Год журнала: 2023, Номер 365(24), С. 4458 - 4494

Опубликована: Ноя. 24, 2023

Abstract The preservation of scarce rare earth metals, such as palladium, rhodium, iridium, and others, poses a significant challenge for humanity due to their limited availability. These metals might be replaced by earth‐abundant 3d‐transition cobalt, manganese, iron, nickel, copper, etc . Isoquinolines have acquired an important position in synthetic organic chemistry well medicinal chemistry. They manifest diverse range natural molecules, serving pivotal synthons the synthesis numerous bioactive compounds with notable significance. Numerous reports on isoquinoline derivatives via transition metal catalysis been published worldwide. In this review, we summarize recent approaches synthesizing various using 3d‐transition‐metal catalysts since 2020. review has divided into different 3d‐transition‐metal‐based catalysis. We expect that will bring better overview present status progress made isoquinolines persuade more advancements research area near future.

Язык: Английский

Процитировано

7

Construction of C–X (X = N, O) bonds from benzyl alcohols via Cu-BTC-catalyzed oxidative coupling DOI

Yujuan Wu,

Lianji Zhang,

Huimin Liu

и другие.

Catalysis Science & Technology, Год журнала: 2024, Номер 14(15), С. 4366 - 4375

Опубликована: Янв. 1, 2024

Herein, an efficient and environmentally friendly Cu-BTC catalytic system is reported, which can be successfully applied to the oxidative coupling of benzyl alcohols for construction C–X (X = N, O) bonds.

Язык: Английский

Процитировано

2

Nickel–PNN catalysed sustainable synthesis of polysubstituted quinolines under microwave irradiation DOI
Manali A. Mohite, Sonu Sheokand, Maravanji S. Balakrishna

и другие.

Catalysis Science & Technology, Год журнала: 2024, Номер 14(20), С. 5959 - 5969

Опубликована: Янв. 1, 2024

This manuscript describes the synthesis of triazolyl-pyridine-based pincer cationic and neutral nickel complexes their application in microwave-assisted quinolines.

Язык: Английский

Процитировано

2

Ruthenium-catalyzed dehydrogenative cyclization to synthesize polysubstituted 4-quinolones under solvent-free conditions DOI

Bitan Sardar,

Debjyoti Pal,

Rajashri Sarmah

и другие.

Chemical Communications, Год журнала: 2023, Номер 59(60), С. 9267 - 9270

Опубликована: Янв. 1, 2023

Herein, we describe acridine-based SNS-Ru pincer-catalysed unprecedented dehydrogenative annulation of alcohols with 2'-aminoacetophenone to synthesize 2,3-disubstituted-4-quinolones. The developed protocol was utilized a wide range various aminoacetophenones. To expand the synthetic utility, 4-quinolones antibiotic properties were synthesized and important post-synthetic modifications scaffolds performed. Various control experiments performed understand mechanism, which showed that C-alkylation has edge over N-alkylation referred possibility in situ alkenylation branched ketones.

Язык: Английский

Процитировано

4

Visible‐Light‐Initiated Dehydrogenative Cyclization of o‐Aminobenzamide and Alcohols for Coproduction of Quinazolinones and Hydrogen over PtS/ZnIn2S4 DOI Open Access
Xiao Du,

Jiaqi Wang,

Hurunqing Liu

и другие.

Solar RRL, Год журнала: 2023, Номер 7(24)

Опубликована: Окт. 9, 2023

PtS/ZnIn2S4 nanocomposites are obtained via a microwave-assisted synthesis followed by photoreduction. The resultant used as an effective multifunctional photocatalyst for the reaction between alcohols and o-aminobenzamide to coproduce quinazolinones hydrogen under visible light, cascade alcohols/aldehydes transformation, condensation aldehydes o-aminobenzamide, well dehydrogenation/cyclization produce quinazolinones. PtS acts efficient cocatalyst promote dehydrogenation of both intermediates production An almost complete conversion was achieved in 24 h, with yield 98.8% 2-phenyl-quinazline-4(3H)-one quantitative produced over after irradiated h. apparent quantum at 450 nm is determined 15.2%. superior activity observed nanocomposite compared that either NiS/ZnIn2S4 or MoS2/ZnIn2S4 can be ascribed moderate binding surface adsorbed H*. This study supplies effective, green, atom-economic strategy coproduction light. work also demonstrates high potential fabrication metal sulfide-based catalysts light-driven one-pot tandem/cascade reactions.

Язык: Английский

Процитировано

4

Catalytic utility of PNN-based MnI pincer complexes in the synthesis of quinolines and transfer hydrogenation of carbonyl derivatives DOI
Manali A. Mohite, Sonu Sheokand, Dipanjan Mondal

и другие.

Dalton Transactions, Год журнала: 2024, Номер 53(12), С. 5580 - 5591

Опубликована: Янв. 1, 2024

This manuscript describes the synthesis and Mn I complexes of triazolyl-pyridine-based phosphine ligand their catalytic utility in quinoline derivatives transfer hydrogenation aldehydes ketones.

Язык: Английский

Процитировано

1

Catalytic Amination of Alcohols Using Diazo Compounds under Manganese Catalysis Through Hydrogenative N‐Alkylation Reaction DOI

Reshma Babu,

Subarna Sukanya Padhy,

Rohit Kumar

и другие.

Chemistry - A European Journal, Год журнала: 2023, Номер 29(61)

Опубликована: Июль 24, 2023

Abstract Sustainable chemical production requires fundamentally new types of catalysts and catalytic technologies. The development coherent robust systems based on earth‐abundant transition metals is essential, but highly challenging. Herein, we systematically explored a general hydrogenative cleavage/N‐alkylation tandem cyclic acyclic diazo (N=N) compounds to value‐added amines under manganese catalysis. reaction catalyzed by single‐site molecular complex proceeds via dehydrogenation, transfer hydrogenation, borrowing hydrogenation strategies. Interestingly, the involves abundantly available renewable feedstocks, such as alcohols, that can act (transfer)hydrogenating alkylating agents. synthetic application our approach in large‐scale pharmaceutical synthesis easy access demanding N ‐CH 3 /CD derivatives are also demonstrated. Kinetic studies show rate depends concentration alcohol Mn‐catalyst follows fractional orders. Several selective bond activation/formation reactions occur sequentially amine–amide metal‐ligand cooperation.

Язык: Английский

Процитировано

3

Accessing 2‐Aryl Quinolines via Acceptorless Dehydrogenation and Transfer Hydrogenation Under Base and Solvent‐Free Reaction Conditions DOI

M. Vageesh,

P. Hima,

R. Prasanna

и другие.

ChemistrySelect, Год журнала: 2023, Номер 8(45)

Опубликована: Дек. 1, 2023

Abstract Catalytic hydrogenation/dehydrogenation reactions are one of the most active areas research for synthesis pharmaceuticals and fine chemicals. Despite several efficient homogeneous catalysts that have already been identified, highly heterogeneous remain elusive. Herein, we report an easy convenient wet impregnation method Pd‐nanoclusters supported on ZnO nanoparticles. The catalyst displays a multifunctional role in 2‐aryl quinolines using alcohol 2‐nitrobenzyl as reactants via dehydrogenation/hydrogenation pathway under neat base‐free reaction conditions. exhibits excellent selectivity can be recycled five times without appreciable loss its activity.

Язык: Английский

Процитировано

3

Acceptorless Dehydrogenation of Alcohols and Transfer Hydrogenation of Aldehydes in Water Using a Single Bifunctional, Bistate, Water‐soluble Ruthenium Catalyst DOI
Susanta Hazra, Abhishek Nair, Pritam Dolui

и другие.

Chemistry - An Asian Journal, Год журнала: 2022, Номер 17(23)

Опубликована: Сен. 19, 2022

A water-soluble bifunctional, bistate ruthenium catalyst has been developed using the 8-aminoquinoline ligand which responds to an acid-base stimuli and is catalytically active for two complementary reactions. The "Ru-amino state" highly catalytic transfer hydrogenation of various aldehydes formic acid as hydrogen source resulting in a range primary alcohols. On other hand, "Ru-amido acceptorless dehydrogenation alcohols yield carboxylate salts or ketones. reactions can be carried out air without inert atmosphere products purified by simple extraction use any chromatographic techniques. functional groups include electron-rich deficient (hetero)arenes alkenes, alkynes, halides, esters, cyano, nitro groups, are all well tolerated, indicating excellent chemoselectivity hydrogenation.

Язык: Английский

Процитировано

3