Chemistry - A European Journal,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 16, 2024
Abstract
After
systematic
realization
of
decarboxylative
functionalization
carboxylic
acids
under
heating
conditions
in
our
group,
we
herein
reported
an
electrochemical
method
for
Ni‐catalyzed
oxygenation
arylacetic
open
air
conditions.
The
protocol
provided
corresponding
carbonyls
including
aldehydes
and
ketones
moderate
to
satisfactory
yields
with
good
functional
group
tolerance,
furthermore,
the
practicability
advantage
was
highlighted
through
oxidative
decarboxylation
acid‐containing
drugs
preformation
scalable
transformation.
Mechanistic
studies
demonstrated
that
possible
involvement
free
radical
intermediate
conversion.
Journal of the American Chemical Society,
Год журнала:
2022,
Номер
144(44), С. 20201 - 20206
Опубликована: Окт. 31, 2022
The
development
of
efficient
and
sustainable
methods
for
decarboxylative
transformations
is
great
importance
due
to
the
ease
availability
nontoxicity
carboxylic
acids.
Despite
tremendous
efforts
in
this
area,
it
remains
challenging
develop
enantioselective
direct
from
Herein
we
disclose
a
photoelectrocatalytic
method
cyanation.
photoelectrochemical
reactions
convert
acids
enantioenriched
nitriles
by
employing
cerium/copper
relay
catalysis
with
cerium
salt
catalytic
decarboxylation
chiral
copper
complex
stereoselective
C-CN
formation.
European Journal of Organic Chemistry,
Год журнала:
2023,
Номер
26(21)
Опубликована: Апрель 7, 2023
Abstract
The
exceptional
versatility
of
carboxylic
acids
has
been
extensively
exploited
in
organic
synthesis
across
several
decades.
There
a
recent
upsurge
radical
decarboxylative
transformations.
process
can
be
initiated
under
mild
conditions,
and
the
resultant
radicals
have
orthogonal
reactivities
to
closed‐shell
species,
thus
providing
immense
opportunities
for
streamlining
novel
reactions.
use
free
is
most
desirable
owing
its
high
atom
step
economy.
Aiming
demonstrate
attractiveness
strategy
inspire
chemists
tackle
existing
challenges,
this
review
outlines
advances
on
functionalization
acids.
Angewandte Chemie International Edition,
Год журнала:
2024,
Номер
63(8)
Опубликована: Янв. 8, 2024
A
mild
photoredox
catalyzed
construction
of
sulfides,
disulfides,
selenides,
sulfoxides
and
sulfones
from
unstrained
ketone
precursors
is
introduced.
Combination
this
deacylative
process
with
S
ACS Organic & Inorganic Au,
Год журнала:
2024,
Номер
4(6), С. 579 - 603
Опубликована: Окт. 2, 2024
Organic
electrosynthesis
has
gained
much
attention
over
the
last
few
decades
as
a
promising
alternative
to
traditional
synthesis
methods.
Electrochemical
approaches
offer
numerous
advantages
organic
procedures.
One
of
most
interesting
aspects
electroorganic
is
ability
tune
many
parameters
affect
outcome
reaction
interest.
such
parameter
composition
working
electrode.
By
changing
electrode
material,
one
can
influence
selectivity,
product
distribution,
and
rate
reactions.
In
this
Review,
we
describe
several
materials
modifications
with
applications
in
electrosynthetic
transformations.
Included
discussion
are
electrodes
nanoparticles,
composite
materials,
polymers,
frameworks,
surface-bound
mediators.
We
first
discuss
important
physicochemical
electrochemical
properties
each
material.
Then,
briefly
summarize
relevant
examples
class
electrodes,
goal
providing
readers
catalog
for
wide
variety
syntheses.
Organic & Biomolecular Chemistry,
Год журнала:
2024,
Номер
22(37), С. 7537 - 7548
Опубликована: Янв. 1, 2024
With
the
development
of
organic
electrochemical
synthesis,
a
series
notable
achievements
have
been
made
in
Ritter
amination
reactions,
which
enriched
methods
available
for
constructing
C-N
bonds.
In
this
review,
reactions
are
introduced
based
on
classification
reaction
substrates,
including
olefins,
aromatics,
alkylbenzenes,
and
less
reported
carboxylic
acids,
ketones,
sulfides,
alkanes.
The
application
technology
to
has
improved
harsh
conditions
traditional
extended
substrate
scope
structural
diversity
products.
value
synthesis
also
further
expanded.
