Fluorescent chemosensors: the past, present and future

Chemical Society Reviews, Год журнала: 2017, Номер 46(23), С. 7105 - 7123

Опубликована: Янв. 1, 2017

Fluorescent chemosensors for ions and neutral analytes have been widely applied in many diverse fields such as biology, physiology, pharmacology, environmental sciences.

Язык: Английский

---

Thioether-Based Fluorescent Covalent Organic Framework for Selective Detection and Facile Removal of Mercury(II)

Journal of the American Chemical Society, Год журнала: 2016, Номер 138(9), С. 3031 - 3037

Опубликована: Фев. 15, 2016

Heavy metal ions are highly toxic and widely spread as environmental pollutants. New strategies being developed to simultaneously detect remove these ions. Herein, we take the intrinsic advantage of covalent organic frameworks (COFs) develop fluorescent COFs for sensing applications. As a proof-of-concept, thioether-functionalized COF material, COF-LZU8, was "bottom-up" integrated with multifunctionality selective detection facile removal mercury(II): π-conjugated framework signal transducer, evenly densely distributed thioether groups Hg2+ receptor, regular pores facilitating real-time mass transfer, together robust structure recycle use. The excellent performance COF-LZU8 achieved in terms high sensitivity, selectivity, easy visibility, response. Meanwhile, efficient from water recycling offers possibility practical In addition, X-ray photoelectron spectroscopy solid-state NMR investigations verified strong interaction between COF-LZU8. This research not only demonstrates utilization both but also highlights construction functionalized

Язык: Английский

---

Luminescent sensors based on metal-organic frameworks

Coordination Chemistry Reviews, Год журнала: 2017, Номер 354, С. 28 - 45

Опубликована: Авг. 1, 2017

Язык: Английский

---

Bio-Integrated Wearable Systems: A Comprehensive Review

Chemical Reviews, Год журнала: 2019, Номер 119(8), С. 5461 - 5533

Опубликована: Янв. 28, 2019

Bio-integrated wearable systems can measure a broad range of biophysical, biochemical, and environmental signals to provide critical insights into overall health status quantify human performance. Recent advances in material science, chemical analysis techniques, device designs, assembly methods form the foundations for uniquely differentiated type technology, characterized by noninvasive, intimate integration with soft, curved, time-dynamic surfaces body. This review summarizes latest this emerging field "bio-integrated" technologies comprehensive manner that connects fundamental developments chemistry, engineering sensing have potential widespread deployment societal benefit care. An introduction chemistries materials active components these contextualizes essential design considerations sensors associated platforms appear following sections. The subsequent content highlights most advanced biosensors, classified according their ability capture information. Additional sections feature schemes electrically powering strategies achieving fully integrated, wireless systems. concludes an overview key remaining challenges summary opportunities where chemistry will be critically important continued progress.

Язык: Английский

---

Metal Sensing by DNA

Chemical Reviews, Год журнала: 2017, Номер 117(12), С. 8272 - 8325

Опубликована: Июнь 9, 2017

Metal ions are essential to many chemical, biological, and environmental processes. In the past two decades, DNA-based metal sensors have emerged. While main biological role of DNA is store genetic information, its chemical structure ideal for binding via both phosphate backbone nucleobases. highly stable, cost-effective, easy modify, amenable combinatorial selection. Two classes functional were developed sensing: aptamers DNAzymes. a few known, it generally quite difficult isolate such aptamers. On other hand, DNAzymes powerful tools sensing since they selected based on catalytic activity, thus bypassing need immobilization. last five years, new surge development has been made isolating metal-sensing sequences. To date, important metals can be selectively detected by often down low parts-per-billion level. Herein, each ion known sequences reviewed. We focus fundamental aspect binding, emphasizing distinct property metal. Instead reviewing published sensor, high-level summary signaling methods as separate section. principle, strategy applied designing sensors. Finally, specific applications highlighted, future research opportunities discussed.

Язык: Английский

---

Discerning the Chemistry in Individual Organelles with Small‐Molecule Fluorescent Probes

Angewandte Chemie International Edition, Год журнала: 2016, Номер 55(44), С. 13658 - 13699

Опубликована: Авг. 29, 2016

Abstract Principle has it that even the most advanced super‐resolution microscope would be futile in providing biological insight into subcellular matrices without well‐designed fluorescent tags/probes. Developments biology have increasingly been boosted by advances of chemistry, with one prominent example being small‐molecule probes not only allow cellular‐level imaging, but also imaging. A majority, if all, chemical/biological events take place inside cellular organelles, and researchers shifting their attention towards these substructures help fluorescence techniques. This Review summarizes existing target within a single organelle. More importantly, organelle‐anchoring strategies are described emphasized to inspire design new generations probes, before concluding future prospects on possible further development chemical biology.

Язык: Английский

---

Highly fluorescent nitrogen-doped carbon dots derived from Phyllanthus acidus utilized as a fluorescent probe for label-free selective detection of Fe3+ ions, live cell imaging and fluorescent ink

Biosensors and Bioelectronics, Год журнала: 2017, Номер 99, С. 303 - 311

Опубликована: Авг. 1, 2017

Язык: Английский

---

The biological inorganic chemistry of zinc ions

Archives of Biochemistry and Biophysics, Год журнала: 2016, Номер 611, С. 3 - 19

Опубликована: Май 1, 2016

The solution and complexation chemistry of zinc ions is the basis for biology. In living organisms, redox-inert has only one valence state: Zn(II). Its coordination environment in proteins limited by oxygen, nitrogen, sulfur donors from side chains a few amino acids. an estimated 10% all human proteins, catalytic or structural function remains bound during lifetime protein. However, other bind reversibly with dissociation association rates commensurate requirements regulation, transport, transfer, sensing, signalling, storage. contrast to extensive knowledge about "mobile" these processes, i.e. when not virtually unexplored mechanisms ligand exchange are poorly understood. Knowledge biological inorganic essential understanding its cellular biology designing complexes that deliver chelating agents remove detecting ion species qualitative quantitative analysis, proper planning execution experiments involving nanoparticles such as oxide (ZnO). most investigations, reference made Zn2+ without full appreciation how buffered d-block cation differs s-block cations Ca2+ regard significantly higher affinity ligands, preference donor atoms dynamics. Zinc needs be tightly controlled. interaction low molecular weight ligands water organic anions highly relevant but been discussed biochemical literature. From discussion this article, it becoming evident speciation important biochemistry recognition variety have already implicated e.g. ATP, glutathione, citrate, ethylenediaminedisuccinic acid, nicotianamine, bacillithiol.

Язык: Английский

---

Chemical sensing with 2D materials

Chemical Society Reviews, Год журнала: 2018, Номер 47(13), С. 4860 - 4908

Опубликована: Янв. 1, 2018

During the last decade, two-dimensional materials (2DMs) have attracted great attention due to their unique chemical and physical properties, which make them appealing platforms for diverse applications in sensing of gas, metal ions as well relevant entities.

Язык: Английский

---

Fluorescent probes and bioimaging: alkali metals, alkaline earth metals and pH

Chemical Society Reviews, Год журнала: 2014, Номер 44(14), С. 4619 - 4644

Опубликована: Окт. 15, 2014

All living species and life forms have an absolute requirement for bio-functional metals acid–base equilibrium chemistry owing to the critical roles they play in biological processes. Hence, a great need exists efficient methods detect monitor biometals acids. In last few years, attention has been paid development of organic molecule based fluorescent chemosensors. The availability new synthetic probes made fluorescence microscopy indispensable tool tracing biologically important molecules area clinical diagnostics. This review highlights recent advances that design bioimaging applications alkali alkaline earth metal cations, including lithium, sodium potassium, magnesium calcium, pH determination within systems.

Язык: Английский

---