Recent Advances of Chiral Isolated and Small Organic Molecules: Structure and Properties for Circularly Polarized Luminescence

Chemistry - An Asian Journal, Год журнала: 2024, Номер 19(9)

Опубликована: Март 7, 2024

Abstract This paper explores recent advancements in the field of circularly polarized luminescence (CPL) exhibited by small and isolated organic molecules. The development application CPL molecule are systematically reviewed through eight different chiral skeleton sections. Investigating intricate interplay between molecular structure properties, aims at providing enlighting novel strategies for CPL‐based applications.

Язык: Английский

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Copper-catalyzed atroposelective synthesis of C–O axially chiral compounds enabled by chiral 1,8-naphthyridine based ligands

Chemical Science, Год журнала: 2024, Номер 15(16), С. 5993 - 6001

Опубликована: Янв. 1, 2024

Axially chiral molecular scaffolds are widely present in therapeutic agents, natural products, catalysts, and advanced materials. The construction of such molecules has garnered significant attention from academia industry. catalytic asymmetric synthesis axially biaryls, along with other non-biaryl molecules, been extensively explored the past decade. However, atroposelective C-O axial chirality remains largely underdeveloped. Herein, we document a copper-catalyzed compounds using novel 1,8-naphthyridine-based ligands. Mechanistic investigations have provided good evidence support mechanism involving synergistic interplay between desymmetrization reaction kinetic resolution process. method described this study holds great significance for compounds, promising applications organic chemistry. utilization ligands copper catalysis is anticipated to find broad copper(i)-catalyzed azide-alkyne cycloadditions (CuAACs) beyond.

Язык: Английский

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Selective multifunctionalization ofN-heterocyclic carbene boranesviathe intermediacy of boron-centered radicals

Chemical Science, Год журнала: 2023, Номер 14(23), С. 6341 - 6347

Опубликована: Янв. 1, 2023

The selective difunctionalization of N-heterocyclic carbene (NHC) boranes with alkenes has been achieved via decatungstate and thiol synergistic catalysis. catalytic system also allows stepwise trifunctionalization, leading to complex NHC three different functional groups which are challenging prepare by other methods. strong hydrogen-abstracting ability the excited enables generation boryl radicals from mono- di-substituted for realizing borane multifunctionalization. This proof-of-principle research provides a new chance fabricating unsymmetrical developing boron-atom-economic synthesis.

Язык: Английский

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Enantioselective copper-catalyzed azidation/click cascade reaction for access to chiral 1,2,3-triazoles

Nature Communications, Год журнала: 2024, Номер 15(1)

Опубликована: Июнь 10, 2024

Chiral 1,2,3-triazoles are highly attractive motifs in various fields. However, achieving catalytic asymmetric click reactions of azides and alkynes for chiral triazole synthesis remains a significant challenge, mainly due to the limited systems substrate scope. Herein, we report an enantioselective azidation/click cascade reaction N-propargyl-β-ketoamides with readily available potent azido transfer reagent via copper catalysis, which affords variety up 99% yield 95% ee under mild conditions. Notably, 1,5-disubstituted triazoles that have not been accessed by previous also prepared good functional group tolerance.

Язык: Английский

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Catalytic insertion of nitrenes into B-H bonds

Chemical Science, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Catalytic insertion of nitrenes into B–H bonds produces unique compounds with chiral boron atoms.

Язык: Английский

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