Organic Letters,
Год журнала:
2023,
Номер
25(33), С. 6099 - 6104
Опубликована: Авг. 14, 2023
A
visible-light-induced
glycoarylation
of
activated
olefins
has
been
accomplished.
Glycosyl
radicals
are
generated
via
radical
transfer
strategies
between
(TMS)3SiOH
and
glycosyl
bromides.
Subsequent
translocation
rapid
1,4-aryl
migration
form
β-sugar
amide
derivatives,
eight
types
sugars
compatible
with
this
reaction.
Further,
the
cascade
reaction
produced
a
quaternary
carbon
center
good
functional
group
adaptability
high
regioselectivity
in
mild
conditions.
Journal of the American Chemical Society,
Год журнала:
2022,
Номер
144(45), С. 20875 - 20883
Опубликована: Окт. 31, 2022
We
report
the
first
palladium
hydride
enabled
hydroalkenylation
of
strained
molecules.
This
new
mild
protocol
proceeds
via
a
regio-
and
chemoselective
hydropalladation
step,
followed
by
photoinduced
radical
alkyl
Heck
reaction.
methodology
represents
reactivity
mode
for
molecules
opens
avenues
catalysis.
The
reaction
is
compatible
with
wide
range
functional
groups
can
be
applied
to
complex
structures,
delivering
diverse
array
highly
valuable
modifiable
alkenylated
cyclobutanes
cyclopropanes.
A
hydroalkenylation/diastereoselective
rearrangement
cascade
toward
cyclopentene
scaffold
has
also
been
demonstrated.
Angewandte Chemie International Edition,
Год журнала:
2023,
Номер
62(38)
Опубликована: Июнь 7, 2023
Glycosyl
radical
functionalization
is
one
of
the
central
topics
in
synthetic
carbohydrate
chemistry.
Recent
advances
metal-catalyzed
cross-coupling
chemistry
and
metallaphotoredox
catalysis
provided
powerful
platforms
for
glycosyl
diversification.
In
particular,
discovery
new
precursors
conjunction
with
these
advanced
reaction
technologies
have
significantly
expanded
space
compound
synthesis.
this
Review,
we
highlight
most
recent
progress
area
starting
from
2021,
reports
included
will
be
categorized
based
on
different
types
better
clarity.
Journal of the American Chemical Society,
Год журнала:
2023,
Номер
145(36), С. 19856 - 19865
Опубликована: Авг. 31, 2023
Introducing
an
external
visible-light
field
would
be
a
promising
strategy
to
improve
the
activity
of
electrocatalytic
CO2
reduction
reaction
(CO2RR),
but
it
still
remains
challenge
due
short
excited-state
lifetime
active
sites.
Herein,
Ru(bpy)3Cl2
struts
as
powerful
photosensitive
donors
were
immobilized
into
backbones
Co-porphyrin-based
covalent
organic
frameworks
(named
Co-Bpy-COF-Rux,
x
is
molar
ratio
Ru
and
Co
species,
=
1/2
2/3)
via
coordination
bonds,
for
photo-coupled
CO2RR
produce
CO.
The
optimal
Co-Bpy-COF-Ru1/2
displays
high
CO
Faradaic
efficiency
96.7%
at
-0.7
V
vs
reversible
hydrogen
electrode
(RHE)
partial
current
density
16.27
mA
cm-2
-1.1
RHE
under
assistance
light,
both
which
far
surpassing
values
observed
in
dark.
significantly
enhanced
mainly
attributed
incorporation
donor
with
long
concomitantly
giant
built-in
electric
Co-Bpy-COF-Ru1/2,
efficiently
accelerate
photo-induced
electron
transfer
from
cobalt-porphyrin
light.
Thus,
sites
have
longer
lower
rate-determining
steps'
energy
occurring
during
actual
process.
This
first
work
porphyrin-based
COFs
CO2RR,
opening
new
frontier
construction
efficient
electrocatalysts.
Angewandte Chemie International Edition,
Год журнала:
2023,
Номер
63(9)
Опубликована: Ноя. 14, 2023
Visible
light-induced
Pd
catalysis
has
emerged
as
a
promising
subfield
of
photocatalysis.
The
hybrid
nature
radical
species
enabled
wide
array
radical-based
transformations
otherwise
challenging
or
unknown
via
conventional
chemistry.
In
parallel
to
the
ongoing
pursuit
alternative,
readily
available
precursors,
notable
discoveries
have
demonstrated
that
photoexcitation
can
alter
not
only
oxidative
addition
but
also
other
elementary
steps.
This
Minireview
highlights
recent
progress
in
this
area.
Chemical Science,
Год журнала:
2024,
Номер
15(4), С. 1204 - 1236
Опубликована: Янв. 1, 2024
This
review
article
highlights
the
diverse
ways
in
which
recent
developments
areas
of
photocatalysis
and
visible
light
photochemistry
are
impacting
synthetic
carbohydrate
chemistry.
Green Chemistry,
Год журнала:
2024,
Номер
26(13), С. 7579 - 7655
Опубликована: Янв. 1, 2024
In
this
review
paper,
recent
developments
of
iron
oxide
nanoparticles
are
highlighted
and
discussed
in
the
field
organic
catalysis
environmental
remediation.
Journal of the American Chemical Society,
Год журнала:
2024,
Номер
146(8), С. 5502 - 5510
Опубликована: Фев. 15, 2024
Glycoproteins
account
for
numerous
biological
processes
including
those
associated
with
diseases
and
infections.
The
advancement
of
glycopeptides
has
emerged
as
a
promising
strategy
unraveling
pathways
discovering
novel
medicines.
In
this
arena,
key
challenge
arises
from
the
absence
efficient
synthetic
strategies
to
access
glycoproteins.
Here,
we
present
highly
concise
approach
bridging
saccharides
amino
acids
peptides
through
an
amide
linkage.
Our
amide-linked
C-glycosyl
are
synthesized
cooperative
Ni-catalyzed
photoredox
processes.
catalytic
process
generates
glycosyl
radical
carbonyl
radical,
which
subsequently
combine
yield
products.
saccharide
reaction
partners
encompass
mono-,
di-,
trisaccharides.
All
20
natural
acids,
peptides,
their
derivatives
can
efficiently
undergo
glycosylations
yields
ranging
acceptable
high,
demonstrating
excellent
stereoselectivities.
As
substantial
expansion
applications,
have
shown
that
simple
function
versatile
building
units
constructing
C-glycopeptides
intricate
spatial
complexities.
JACS Au,
Год журнала:
2022,
Номер
2(5), С. 1032 - 1042
Опубликована: Апрель 11, 2022
Spin-center
shift
(SCS)
is
a
radical
process
involving
1,2-radical
translocation
along
with
two-electron
ionic
movement,
such
as
elimination
of
an
adjacent
leaving
group.
Such
was
initially
observed
in
some
important
biochemical
transformations,
and
the
unique
property
has
also
attracted
considerable
interest
synthetic
chemistry.
Experimental,
kinetic,
well
computational
studies
have
been
performed,
series
useful
transformations
developed
applied
organic
synthesis
based
on
SCS
processes
last
20
years.
This
Perspective
overview
mechanism.
