The Journal of Organic Chemistry,
Год журнала:
2022,
Номер
87(21), С. 14715 - 14722
Опубликована: Окт. 11, 2022
1,5-Hydrogen
atom
transfer
(HAT)
is
an
effective
strategy
to
achieve
remote
desaturation
of
nonfunctionalized
alkanes.
Herein,
we
report
a
photoinduced
reaction
N-alkoxypyridinium
salts,
which
serve
as
alkoxyl
radical
precursors.
Mechanistic
studies
show
that
single
electron
between
the
excited
palladium
complex
and
salt
initiates
chain
process
leading
salts.
This
mechanism
supported
by
measurement
quantum
yield
this
(Φ
=
82).
applicable
range
including
some
molecule-derived
ones.
Chemical Reviews,
Год журнала:
2022,
Номер
122(22), С. 16365 - 16609
Опубликована: Ноя. 9, 2022
Photocatalyzed
and
photosensitized
chemical
processes
have
seen
growing
interest
recently
become
among
the
most
active
areas
of
research,
notably
due
to
their
applications
in
fields
such
as
medicine,
synthesis,
material
science
or
environmental
chemistry.
Among
all
homogeneous
catalytic
systems
reported
date,
photoactive
copper(I)
complexes
been
shown
be
especially
attractive,
not
only
alternative
noble
metal
complexes,
extensively
studied
utilized
recently.
They
are
at
core
this
review
article
which
is
divided
into
two
main
sections.
The
first
one
focuses
on
an
exhaustive
comprehensive
overview
structural,
photophysical
electrochemical
properties
mononuclear
typical
examples
highlighting
critical
structural
parameters
impact
being
presented
enlighten
future
design
complexes.
second
section
devoted
application
(photoredox
catalysis
organic
reactions
polymerization,
hydrogen
production,
photoreduction
carbon
dioxide
dye-sensitized
solar
cells),
illustrating
progression
from
early
current
state-of-the-art
showcasing
how
some
limitations
can
overcome
with
high
versatility.
Chemical Society Reviews,
Год журнала:
2024,
Номер
53(3), С. 1068 - 1089
Опубликована: Янв. 1, 2024
Leveraging
light
energy
to
expose
the
‘dark’
reactive
states
describes
whole
essence
of
triplet–triplet
transfer.
This
offers
an
impressive
opportunity
conduct
a
multitude
diverse
reactions
and
access
sought-after
molecular
motifs.
Angewandte Chemie International Edition,
Год журнала:
2023,
Номер
62(25)
Опубликована: Апрель 15, 2023
Abstract
A
visible
light
photosensitizing
metal‐organic
cage
is
applied
as
an
artificial
supramolecular
reactor
to
control
the
reaction
of
aryl
radicals
with
terminal
olefins
under
green
light/solvent
conditions,
which
facilitates
selective
transformation
in
confined
enzyme‐mimicking
environment
give
a
series
geometrically
defined
E
/
Z
‐alkenes.
The
hydrophobic
displays
good
host–guest
inclusion
aromatic
substrates,
promoting
Meerwein
arylation
and
protecting
‐isomeric
products
during
reaction;
while
small
amount
benzonitrile
can
turn
on
efficient
→
isomerization.
Besides
π–π
stacking,
hydrogen
bonding
halogen
interactions
also
act
forces
for
aliphatic
known
poor
acceptors
classic
arylation.
application
this
switchable
cage‐confined
catalysis
has
been
demonstrated
by
syntheses
Tapinarof
marine
natural
product
from
same
substrate
via
controllable
selectivity.
Journal of the American Chemical Society,
Год журнала:
2024,
Номер
146(30), С. 21137 - 21146
Опубликована: Июль 18, 2024
The
different
enantiomers
of
specific
chiral
molecules
frequently
exhibit
disparate
biological,
physiological,
or
pharmacological
properties.
Therefore,
the
efficient
synthesis
single
is
particular
importance
not
only
to
pharmaceutical
sector
but
also
other
industrial
sectors,
such
as
agrochemical
and
fine
chemical
industries.
Deracemization,
a
process
during
which
racemic
mixture
converted
into
nonracemic
product
with
100%
atom
economy
theoretical
yield,
most
straightforward
method
access
enantioenriched
challenging
task
due
decrease
in
entropy
microscopic
reversibility.
Axially
allenes
bear
distinctive
structure
two
orthogonal
cumulative
π-systems
are
acknowledged
synthetically
versatile
synthons
organic
synthesis.
selective
creation
axially
high
optical
purity
under
mild
reaction
conditions
has
always
been
very
popular
hot
topic
remains
challenging.
Herein,
photoexcited
palladium-catalyzed
deracemization
nonprefunctionalized
disubstituted
disclosed.
This
provides
an
economical
strategy
accommodate
broad
scope
good
enantioselectivities
yields
(53
examples,
up
96%
yield
95%
ee).
use
suitable
palladium
complex
visible
light
irradiation
essential
factor
achieving
this
transformation.
A
metal-to-ligand
charge
transfer
mechanism
was
proposed
based
on
control
experiments
density
functional
theory
calculations.
Quantum
mechanical
studies
implicate
dual
modes
asymmetric
induction
behind
our
new
protocol:
(1)
sterically
controlled
stereoselective
binding
one
allene
enantiomer
ground-state
(2)
facile,
noncovalent
interaction-driven
excited-state
isomerization
toward
opposite
enantiomer.
success
newly
established
photochemical
should
provide
inspiration
for
expansion
multisubstituted
will
open
mode
enantioselective
catalysis.
Angewandte Chemie International Edition,
Год журнала:
2024,
Номер
63(44)
Опубликована: Июль 13, 2024
Allylic
amines
are
prevalent
and
vital
structural
components
present
in
many
bioactive
compounds
natural
products.
Additionally,
they
serve
as
valuable
intermediates
building
blocks,
with
wide-ranging
applications
organic
synthesis.
However,
direct
α-C(sp
ACS Catalysis,
Год журнала:
2024,
Номер
14(16), С. 11974 - 11989
Опубликована: Июль 26, 2024
Photoactive
copper
complexes
have
gained
significant
attention
due
to
their
photocatalytic
activities.
Different
homogeneous
Cu(I)
complexes,
Cu(II)
and
heterogeneous
copper-based
photocatalysts
been
investigated
utilized
in
a
broad
spectrum
of
organic
transformations.
These
applications
span
radical
additions,
C–C
bond
C–heteroatom
cross-couplings,
aerobic
oxidative
reactions,
kinetic
resolutions.
This
review
summarizes
the
advancements
this
dynamic
field
visible-light-induced,
excited-state
copper-catalyzed
reactions
over
recent
years.
It
is
organized
according
type
excited
species
involved
provides
perspective
on
current
future
developments.
Journal of the American Chemical Society,
Год журнала:
2024,
Номер
146(39), С. 27196 - 27203
Опубликована: Сен. 17, 2024
The
functionalization
of
C-H
bonds
streamlines
the
synthesis
complex
molecules
by
eliminating
need
for
substrate
preactivation.
Traditionally,
Kharasch-Sosnovsky
reaction,
which
directly
oxidizes
allylic
into
esters
under
copper
catalysis,
has
been
hampered
long
reaction
times,
limited
scope,
and
low
enantioselectivity
with
acyclic
olefins.
Herein,
we
present
a
novel,
visible
light-driven,
copper-catalyzed
asymmetric
that
overcomes
these
challenges.
This
method
expands
scope
to
include
internal
alkenes
improves
conditions
using
eco-friendly
light
catalysis.
It
enhances
radical
reactivity
achieves
superior
regioselectivity
in
producing
acyloxylation
products.
breakthrough
significantly
advances
direct
techniques,
offering
more
efficient
sustainable
approach
synthesizing
chiral
molecules.
