Cobalt‐Catalyzed Hydrogenation and Deuteration Reactions of Bicyclic Alkenes in an Aqueous Environment

European Journal of Organic Chemistry, Год журнала: 2024, Номер 27(11)

Опубликована: Янв. 27, 2024

Abstract Herein, we report cobalt‐catalyzed hydrogenation and deuteration reactions of bicyclic alkenes using H 2 O D as the sole hydrogen deuterium sources, respectively, employing Zn or Mn a metal reductant. Lewis‐acid co‐catalysts were found to promote reaction whilst simultaneously catalyzing transesterification processes. Use 1 atm allows for catalytic loading In all cases, operated with high functional‐group tolerance produced reduced products in yield.

Язык: Английский

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Hydrogenation of Alkenes Catalyzed by Mn(I) Alkyl Complexes Bearing NHC Phosphine Ligands

ChemCatChem, Год журнала: 2024, Номер 16(22)

Опубликована: Авг. 10, 2024

Abstract An efficient additive free hydrogenation of alkenes with molecular hydrogen is described. The pre‐catalyst a well‐defined bench stable Mn(I) alkyl complex bearing NHC phosphine ligand. These reactions are environmentally benign and atom economic, implementing an inexpensive, earth abundant non‐precious metal catalyst. catalytic process initiated by migratory insertion CO ligand into the Mn‐alkyl bond to yield acyl intermediate which undergoes rapid hydrogenolysis form active 16e hydride catalyst [Mn(PC‐ i Pr)(CO) 2 (H)]. A range mono‐ disubstituted were efficiently converted alkanes in good excellent yields. requires reaction temperature 60 °C. In all cases, loading 1 mol % pressure 50 bar was applied. mechanism based on DFT calculations presented supported experimental studies.

Язык: Английский

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Photocatalytic Hydrogenation of Alkenes Using Water as Both the Reductant and the Proton Source

Advanced Science, Год журнала: 2024, Номер 11(44)

Опубликована: Окт. 9, 2024

Abstract Utilization of clean and low‐cost water as the reductant to enable hydrogenation alkenes is highly attractive in green chemistry. However, this research subject considerably challenging due sluggish kinetics oxidation half‐reaction. It also very difficult avoid undesired because that far easier occur than desired from thermodynamic standpoint. Herein, challenge overcome by applying a cooperative catalysis where HCl used cocatalyst accelerate Pt/g‐C 3 N 4 ‐catalyzed suppress alkene. This provides an example for using proton source photocatalytic alkenes. The present method exhibits broad substrate applicability, allows various arylethenes aliphatic undergo smoothly.

Язык: Английский

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Cobalt-Catalyzed Enantioselective Reductive Amination of Ketones with Hydrazides

Organic Letters, Год журнала: 2023, Номер 26(4), С. 769 - 774

Опубликована: Дек. 4, 2023

An efficient cobalt-catalyzed asymmetric reductive amination of ketones with hydrazides has been realized, directly producing valuable chiral hydrazines in high yields and enantioselectivities (up to 98% enantiomeric excess).

Язык: Английский

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Exploration of Quinim Ligand in Ni-Catalyzed Enantioselective Reductive Carbamoyl-Alkylation of Alkene

Chinese Journal of Organic Chemistry, Год журнала: 2023, Номер 43(12), С. 4239 - 4239

Опубликована: Янв. 1, 2023

Язык: Английский

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