Angewandte Chemie,
Год журнала:
2024,
Номер
unknown
Опубликована: Авг. 24, 2024
Abstract
Our
interest
in
the
design
of
heavy
pnictogen‐based
Lewis
acids
for
anion
trafficking
across
biological
membrane
mimics
has
led
us
to
investigate
trivalent
bismuthenium
cations
as
chloride
transporters.
Here,
we
describe
two
chlorodiarylbismuthines,
elaborated
on
a
peri
‐substituted
naphthalene
backbone
and
stabilized
by
an
adjacent
thio‐
or
seleno‐ether
functionality
that
engages
bismuth
center
Ch→Bi
interaction
(Ch=chalcogen).
These
new
derivatives
are
stable
aqueous
environment
readiliy
transport
anions
phospholipid‐based
vesicles
loaded
with
KCl.
In
addition
establishing
use
such
motifs
transport,
this
investigation
shows
acidity,
lipophilicity,
thus
properties
depend
nature
chalcogen.
Dalton Transactions,
Год журнала:
2024,
Номер
53(20), С. 8524 - 8534
Опубликована: Янв. 1, 2024
The
synthetic
strategies
employed
to
isolate
monomeric
stibinidene
chalcogenides
(RSbCh)
and
stibine
(R
3
SbCh)
are
discussed,
a
perspective
on
the
outcomes
future
directions
of
this
exciting
area
is
provided.
Organometallics,
Год журнала:
2024,
Номер
43(11), С. 1246 - 1255
Опубликована: Май 29, 2024
With
an
interest
in
chalcogen
bonding,
we
use
a
rigid
indazolium
backbone
to
install
formally
zero-valent
Se
center
next
divalent
Te
center,
allowing
us
investigate
the
effects
of
oxidation
on
observed
Te···Se
interaction.
Through
spectroscopic
and
computational
comparison
Se(0)
species
with
its
Se(II)
counterpart
their
monochalcogen
analogues,
experimentally
computationally
effect
modulating
basicity
resulting
Comparison
well-studied
naphthalene
acenaphthene
variants
indicates
that
increased
allows
for
comparably
strong
interaction
despite
longer
peri
distances
larger
splay
angle.
Finally,
our
study
illuminates
potential
non-innocence
cationic
organic
substituents
chalcogen-bonding
catalysis
transfer
hydrogenation
quinolines.
Organic Letters,
Год журнала:
2023,
Номер
26(1), С. 344 - 349
Опубликована: Дек. 26, 2023
In
this
study,
we
present
a
nickel-catalyzed
reductive
C(sp3)–Sb
coupling
of
unactivated
alkyl
chlorides
with
chlorostibines.
This
approach
is
highly
versatile,
tolerating
various
functional
groups
such
as
acetal,
alkene,
nitrile,
amine,
ester,
silyl
ether,
thioether,
and
heterocyclic
compounds.
Notably,
the
late-stage
modification
bioactive
molecules
satisfactory
anticancer
activity
against
cancerous
MDA-MB-231
also
demonstrate
potential
application.
Angewandte Chemie,
Год журнала:
2024,
Номер
136(31)
Опубликована: Май 10, 2024
Abstract
Die
Anwendung
nichtkovalenter
Wechselwirkungen,
welche
auf
elektrophilen
Halogen‐,
Chalkogen‐,
Pniktogen‐
oder
Tetrelzentren
beruhen,
hat
in
der
Organokatalyse
deutlich
an
Aufmerksamkeit
gewonnen.
Wir
geben
hier
einen
Überblick
über
die
wichtigsten
Entwicklungen
letzten
Jahre,
mit
einem
Fokus
experimentellen
Studien
und
Katalysatoren,
nicht‐transiente
derartige
Welchselwirkungen
agieren.
Journal of the American Chemical Society,
Год журнала:
2024,
Номер
146(28), С. 19350 - 19359
Опубликована: Июль 3, 2024
Phosphine
oxides
and
arsine
are
common
laboratory
reagents
with
diverse
applications
that
stem
from
the
chemistry
exhibited
by
these
monomeric
species.
Stibine
are,
in
contrast,
generally
dimeric
or
oligomeric
species
because
of
reactivity-quenching
self-association
highly
polarized
stiboryl
(Sb=O/Sb+–O–)
group.
We
recently
isolated
Dipp3SbO
(Dipp
=
2,6-diisopropylphenyl),
first
example
a
kinetically
stabilized
stibine
oxide,
which
exists
as
bench-stable
solid
bears
an
unperturbed
Herein,
we
report
isolation
Mes3SbO
(Mes
mesityl),
less
bulky
substituents
maintain
nature
compound
but
unlock
access
to
wider
range
reactivity
at
group
relative
Dipp3SbO.
was
found
be
potent
Lewis
base
formation
adducts
main-group
acids
PbMe3Cl
SnMe3Cl.
The
accessible
acidity
Sb
atom
results
change
GeMe3Cl,
SiMe3Cl,
CPh3Cl.
With
species,
formally
adds
E–Cl
(E
Ge,
Si,
C)
bond
across
unsaturated
form
5-coordinate
stiborane.
biphilicity
is
sufficiently
activate
even
C–F
Si–F
bonds
C(p-MeOPh)3F
SiEt3F,
respectively.
These
mark
significant
contribution
increasingly
rich
literature
on
polar,
motifs.
Furthermore,
highlight
utility
kinetic
stabilization
approach
unusual
bonding
motifs
unquenched
can
leveraged
for
small-molecule
activation.
Organometallics,
Год журнала:
2024,
Номер
43(19), С. 2334 - 2341
Опубликована: Сен. 26, 2024
Our
interest
in
the
design
of
ambiphilic
ligands
and
their
coordination
to
gold
has
led
us
synthesize
an
indazol-3-ylidene
chloride
complex
functionalized
at
4-position
indazole
backbone
by
a
stibine
functionality.
The
antimony
center
this
new
cleanly
reacts
with
Angewandte Chemie,
Год журнала:
2024,
Номер
136(45)
Опубликована: Июль 5, 2024
Abstract
The
objective
of
this
study
was
to
create
artificial
enzymes
that
capitalize
on
pnictogen
bonding,
a
σ‐hole
interaction
is
essentially
absent
in
biocatalysis.
For
purpose,
stibine
catalysts
were
equipped
with
biotin
derivative
and
combined
streptavidin
mutants
identify
an
efficient
transfer
hydrogenation
catalyst
for
the
reduction
fluorogenic
quinoline
substrate.
Increased
catalytic
activity
from
wild‐type
best
coincides
depth
σ
hole
Sb(V)
center,
emergence
saturation
kinetic
behavior.
Michaelis–Menten
analysis
reveals
transition‐state
recognition
low
micromolar
range,
more
than
three
orders
magnitude
stronger
millimolar
substrate
recognition.
Carboxylates
preferred
by
contribute
hydrogen‐bonded
ion
pairing
anion‐π
interactions
emerging
pyridinium
product.
challenging
stereoselectivity
aqueous
systems
further
emphasizes
compatibility
bonding
higher
order
catalysis.
Angewandte Chemie International Edition,
Год журнала:
2024,
Номер
unknown
Опубликована: Авг. 24, 2024
Our
interest
in
the
design
of
heavy
pnictogen-based
Lewis
acids
for
anion
trafficking
across
biological
membrane
mimics
has
led
us
to
investigate
trivalent
bismuthenium
cations
as
chloride
transporters.
Here,
we
describe
two
chlorodiarylbismuthines,
elaborated
on
a
peri-substituted
naphthalene
backbone
and
stabilized
by
an
adjacent
thio-
or
seleno-ether
functionality
that
engages
bismuth
center
Ch→Bi
interaction
(Ch=chalcogen).
These
new
derivatives
are
stable
aqueous
environment
readiliy
transport
anions
phospholipid-based
vesicles
loaded
with
KCl.
In
addition
establishing
use
such
motifs
transport,
this
investigation
shows
acidity,
lipophilicity,
thus
properties
depend
nature
chalcogen.
