Palladium(I)-Catalyzed Cross-Electrophile Coupling of Vinyl Triflates and Aryl Iodides DOI
Mark Lautens, Alexa Torelli

Synfacts, Год журнала: 2023, Номер 20(01), С. 0041 - 0041

Опубликована: Дек. 8, 2023

Язык: Английский

Radicalizing CO by Mononuclear Palladium(I) DOI Creative Commons

Tim Bruckhoff,

Joachim Ballmann, Lutz H. Gade

и другие.

Angewandte Chemie International Edition, Год журнала: 2024, Номер 63(19)

Опубликована: Март 18, 2024

Abstract A mononuclear, T‐shaped palladium(I) d 9 metalloradical ( 3 ), stabilized by a bulky carbazole‐based PNP‐ligand, was obtained reduction of palladium chloride or thermal Pd−C bond homolysis the corresponding neopentyl complex. Pressurizing with CO gave Pd(I) carbonyl complex, which structurally characterized X‐ray diffraction. Delocalization unpaired electron to carbon detected EPR spectroscopy and theoretically modeled DFT ab initio methods. The partially reduced radicalized slowly reacts di( tert ‐butyl) disulfide under homolytic S−S cleavage C−S formation give metallathioester.

Язык: Английский

Процитировано

8
Pd-Catalyzed Enantioselective Three-Component Carboamination of 1,3-Cyclohexadiene DOI

Jinrong Wang,

Bing Xu, Yibo Wang

и другие.

Journal of the American Chemical Society, Год журнала: 2024, Номер 146(31), С. 21231 - 21238

Опубликована: Июль 29, 2024

Asymmetric Pd-catalyzed three-component carboamination reactions of dienes to construct chiral cyclohexenylamines, which are great importance in many fields chemistry, have remained largely unexplored. Here, we demonstrate a highly enantio- and regioselective Pd/Ming-Phos-catalyzed 1,3-cyclohexadiene with readily available aryl iodides anilines for facile access diverse valuable cyclohexenylamines. The process shows excellent functional group tolerance, easy scalability, mild conditions. Moreover, mechanistic studies suggest that this reaction has first-order dependence on the concentration palladium catalyst aniline.

Язык: Английский

Процитировано

8
Aryl halide cross-coupling via formate-mediated transfer hydrogenation DOI
Yoon Cho, Yu-Hsiang Chang, Kevin P. Quirion

и другие.

Nature Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Март 11, 2025

Язык: Английский

Процитировано

1
Formate-Mediated C–C Coupling of Aryl/Vinyl Halides and Triflates: Carbonyl Arylation and Reductive Cross-Coupling DOI
Yu-Hsiang Chang, Yoon Cho, Weijia Shen

и другие.

ACS Catalysis, Год журнала: 2025, Номер unknown, С. 8274 - 8283

Опубликована: Май 2, 2025

Язык: Английский

Процитировано

0
Alkylide derivatives of diphyllin: synthesis and preliminary anticancer evaluation DOI

Chenhu Dong,

Hui Wang, Yu-Jie Ma

и другие.

Journal of Asian Natural Products Research, Год журнала: 2024, Номер 26(7), С. 833 - 842

Опубликована: Апрель 7, 2024

Fourteen diphyllin 4-C-substituted alkylide derivatives were designed and synthesized using a Heck coupling subsequent hydrogenation reaction. Olefins 3g 3i exhibited the highest cytotoxicity on breast cancer cell lines MCF-7 with IC50 values of 0.08 0.07 µM, they showed weaker V-ATPase inhibitory potency compared to diphyllin.

Язык: Английский

Процитировано

2
Cine-Substitution of Enolates: Enolate Dance/Coupling of Cycloalkenyl Pivalates by Nickel Catalysis DOI

Eito Moriya,

Kei Muto, Junichiro Yamaguchi

и другие.

ACS Catalysis, Год журнала: 2024, Номер 14(13), С. 10412 - 10417

Опубликована: Июнь 26, 2024

This manuscript describes the development of Ni/dcype-catalyzed enolate dance/coupling reaction alkenyl pivalates with nucleophiles, resulting in cine-substitution. Pivalates derived from 1-tetralone undergo this to produce C2-functionalized dihydronaphthalenes. The direct utilization is also feasible, employing Piv2O generate corresponding enol pivalate situ. Mechanistic investigations, including stoichiometric experiments, suggest that proceeds via C–O oxidative addition, nickel 1,2-translocation, and subsequent coupling a nucleophile.

Язык: Английский

Процитировано

2
Formate-Mediated Reductive Cross-Coupling of Vinyl Halides and Aryl Iodides: cine-Substitution via Palladium(I) Catalysis DOI
Catherine G. Santana,

Yhin Sarah Teoh,

Madeline M. Evarts

и другие.

Organic Letters, Год журнала: 2024, Номер 26(33), С. 7055 - 7059

Опубликована: Авг. 12, 2024

Formate-mediated reductive cross-couplings of vinyl halides with aryl iodides via palladium(I) catalysis occur highly uncommon

Язык: Английский

Процитировано

2
Useful 1,2-dioxygenated dienes: syntheses and Diels–Alder reactions en route to substituted 2-naphthols and phenols DOI

Jiabing Teng,

Xifang Zhang, Ying Song

и другие.

Organic Chemistry Frontiers, Год журнала: 2024, Номер 11(20), С. 5914 - 5920

Опубликована: Янв. 1, 2024

The alkenylation reaction of vinylene carbonate with vinyl triflates using a Pd catalyst provides an access to 1,2-dioxygenated dienes, which undergo tandem DA cycloaddition/decarboxylative aromatization give 2-naphthols and phenols.

Язык: Английский

Процитировано

2
An overview: dinuclear palladium complexes for organic synthesis DOI
Sarita Yadav,

Sangeeta Yadav,

Mookan Natarajan

и другие.

Catalysis Science & Technology, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

From materials science and polymer chemistry to organic synthesis medicinal chemistry, cross-coupling has influenced many scientific fields.

Язык: Английский

Процитировано

1
Trendbericht Organische Chemie 2024 DOI Open Access
Martin Breugst, Jennifer N. Andexer,

Lena Barra

и другие.

Nachrichten aus der Chemie, Год журнала: 2024, Номер 72(3), С. 44 - 67

Опубликована: Фев. 29, 2024

Abstract Unter anderem das hat die Organik im letzten Jahr bewegt: milde Oxidation mit Elektrochemie, zu enantiomerenreinen Sulfonylverbindungen, Flüssigkristallphasen erkennen maschinellem Lernen, CO 2 reagiert Succinat und Carbamaten, eine Alternative Bisphenol A, Subporphyrine, photoschaltbare Spinmaterialien, photochemische Thiophen‐Ringerweiterung, Peptide werden Bor versehen cyclisiert. Die Zusammenstellung des Trendberichts koordiniert Martin Breugst, Universität Chemnitz.

Процитировано

0