Structural characteristics, sugar metabolizing enzyme activity and biological activity of Ganoderma lucidum polysaccharides at different growth stages
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Фев. 9, 2025
The
Ganoderma
lucidum
polysaccharides
(GLPs)
content,
monosaccharide
composition,
molecular
weight,
sugar
metabolism-related
enzyme
activities
and
in
vitro
antioxidant
of
fruiting
body
(GLFB)
from
cassava
stalk
cultivation
at
different
growth
stages
(namely,
differentiation
stage,
umbrella
maturity
stage
spore
stage)
were
determined.
results
showed
that
the
monosaccharides
GLPs
GLFB
mainly
composed
galactose,
glucose,
mannose.
During
maturation
GLFB,
polysaccharide
hexose
kinase
phosphoglucose
isomerase
an
increasing
trend,
structure
functional
groups
did
not
change
significantly,
weight
a
tendency
to
increase
(112
kDa
up
11358
kDa)
then
decrease
(11358
down
7678
kDa).
Of
four
stages,
had
highest
content
4.11%,
hexokinase
(HK)
(PGM)
4051.4
322.1
nmol/(min/g),
respectively,
total
activity
(18.79
mmol/mL)
DPPH
radical
scavenging
capacity
(36.15%).
This
study
provided
theoretical
basis
for
application
stalks
harvesting.
Язык: Английский
Research progress on structural characterization and bioactivities of Poria cocos and Ganoderma polysaccharides
Food & medicine homology.,
Год журнала:
2024,
Номер
2(1), С. 9420040 - 9420040
Опубликована: Сен. 18, 2024
Язык: Английский
A Ligand-Controlled Approach Enabling Gold(I)-Catalyzed Stereoinvertive Glycosylation with Primal Glycosyl ortho-Alkynylbenzoate Donors
Journal of the American Chemical Society,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 24, 2024
A
diarylurea-containing
phosphine
ligand-modulated
stereoinvertive
Язык: Английский
Development of Glycosylation Protocols Using Glycosyl N-Phenylethynyl Pyrrole-2-carboxylates as Donors
Organic Letters,
Год журнала:
2024,
Номер
26(46), С. 9926 - 9930
Опубликована: Ноя. 12, 2024
We
herein
introduce
glycosyl
Язык: Английский
One-Pot Assembly of Octasaccharide Motif from Cranberry Arabinoxyloglucan Oligosaccharides
Synlett,
Год журнала:
2024,
Номер
unknown
Опубликована: Июнь 30, 2024
Abstract
Chemical
synthesis
of
octasaccharide
motif
from
cranberry
arabinoxyloglucan
oligosaccharides
with
antiadhesion
activities
has
been
achieved
for
the
first
time.
Synthetic
approach
highlights
following
features:
1)
stereoselective
constructions
1,2-cis-Xyl
bonds
via
combination
reagent
modulation
and
remote
participation;
2)
modular
[1+3+1+3]
orthogonal
one-pot
assembly
target
on
basis
glycosyl
ortho-(1-phenylvinyl)benzoate,
which
avoids
issues
such
as
aglycone
transfer
associated
glycosylation
based
thioglycosides.
Язык: Английский
ZnI2-Mediated cis-Glycosylations of Various Constrained Glycosyl Donors: Recent Advances in cis-Selective Glycosylations
Molecules,
Год журнала:
2024,
Номер
29(19), С. 4710 - 4710
Опубликована: Окт. 4, 2024
An
efficient
and
versatile
glycosylation
methodology
is
crucial
for
the
systematic
synthesis
of
oligosaccharides
glycoconjugates.
A
direct
intermolecular
an
indirect
intramolecular
have
been
developed,
former
can
be
applied
to
medium-to-long-chain
glycans
like
that
nucleotides
peptides.
The
development
a
generally
applicable
approach
stereoselective
construction
glycosidic
bonds
remains
major
challenge,
especially
1,2-
Язык: Английский
Total Synthesis of the Conjugation‐Ready Hexasaccharides of Pseudomonas aeruginosa Serotype O17 O‐Antigen via One‐Pot Glycosylation
Chinese Journal of Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 28, 2024
Comprehensive
Summary
The
eradication
of
Pseudomonas
aeruginosa
infections
is
becoming
increasingly
complex
due
to
the
emergence
multidrug‐resistant
strains,
underscoring
urgent
need
for
novel
therapeutic
strategies.
Currently,
no
vaccine
available
prevent
P.
and
development
glycoconjugate
vaccines
based
on
lipopolysaccharides
(LPS)
presents
significant
challenges.
To
explore
immunological
activity
serotype
O17
O‐antigen,
we
present
first
chemical
synthesis
two
hexasaccharides
derived
from
O‐antigen
,
which
possess
distinct
sequences.
these
target
was
accomplished
using
a
chemoselective
one‐pot
[2+2+2]
assembly
strategy
common
step‐wise
synthesis,
respectively.
formation
β‐mannosamine
glycosidic
linkages
in
products
1
2
achieved
through
direct
stereoselective
1,2‐
cis
‐glycosylation
involving
4,6‐
O
‐benzylidene‐induced
conformational
locking
facilitated
by
Ph
SO/Tf
pre‐activation,
an
indirect
trans
‐β‐glycosylation
alongside
S
N
substitution
azide
groups
at
C2,
efficient
conjugation‐ready
oligosaccharides
will
provide
foundational
materials
identifying
key
antigens
developing
vaccines.
Язык: Английский
Chemical synthesis of rhynchosporosides
Journal of Carbohydrate Chemistry,
Год журнала:
2024,
Номер
unknown, С. 1 - 10
Опубликована: Окт. 11, 2024
Chemical
synthesis
of
rhynchosporosides
that
cause
scald
diseases
in
barley
has
been
summarized
this
review.
The
features
two
different
strategies,
namely,
two-stage
activation
and
one-pot
glycosylation.
Comparing
with
the
stepwise
synthesis,
assembly
strategy
based
on
glycosyl
ortho-(1-phenylvinyl)benzoates
can
highly
streamline
carbohydrates
avoiding
such
problems
as
aglycone
transfer
associated
traditional
glycosylation
thioglycosides.
Язык: Английский