ACS Applied Bio Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 19, 2024
Afterglow
fluorescence
imaging
has
been
extensively
assessed
in
ultrasensitive
bioimaging.
Since
it
eliminates
the
need
for
real-time
excitation
light
and
thereby
circumvents
autofluorescence
background
of
tissue,
holds
tremendous
potential
accurate
biomedical
imaging.
However,
current
afterglow
probes
are
rare
emit
only
visible
to
near-infrared
(NIR)
range,
which
is
inadequate
vivo
To
resolve
this
issue,
an
ultrasound
(US)-activated
NIR-II
luminescence
probe
(NPs-Ce4-SN)
emitting
with
a
peak
at
∼1100
nm
was
developed.
This
nearly
400
red-shifted
compared
other
reported
probes.
Of
note,
after
US
termination,
NPs-Ce4-SN
undergoes
energy
transformation
produce
1O2
subsequently
internal
oxidation-reduction
reaction
afterglow,
generating
high
signal-to-noise
ratio
high-penetration
depth
In
vitro
experiments
revealed
that
good
biocompatibility
deep
tissue
penetration
depth,
suggesting
diagnostic
strategy
tumor
ratio.
Stimulus-responsive
covalent
organic
frameworks
(COFs)
own
color-switching
characteristics
when
exposed
to
external
stimuli.
However,
the
investigations
on
multiple
solvent-responsive
COFs
remain
a
challenge
due
synthetic
difficulties
and
uncontrollable
charge
transfer
process
toward
various
solvents.
In
this
contribution,
two
novel
isomeric
with
regulated
intramolecular
(ICT)
by
modulating
distance
between
donor/acceptor
linkage
are
synthesized.
The
as-prepared
exhibited
significantly
distinct
solvatochromic
behaviors
in
water,
acid,
halogenated
solvents,
respectively.
These
functions
attributed
enhancement
degrees
of
ICT
hydrogen
bond
interactions,
protonation
halogen/π
addition,
employed
as
stimulation-responsive
powder
or
ink,
displaying
excellent
image
data
encryption
performances.
work
can
not
only
offer
viewpoint
for
creation
but
also
expand
COFs'
potential
applications
information
anti-counterfeiting.
