Exploring the Site Selectivity of Arene Oxidation in [(η5-C5Me5)Ir(η6-arene)](OTf)2 Complexes DOI
Carlota Odena, Marina Pérez‐Jiménez, Ronghui Lin

и другие.

Organometallics, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 26, 2024

The oxidation selectivity of the η6-arene ligand in a series [(η5-C5Me5)Ir(η6-arene)](OTf)2 complexes to corresponding [(η5-C5Me5)Ir(η5-phenoxo)](OTf) derivatives was studied as complementary protocol metal-catalyzed borylation-oxidation. A representative compounds prepared with mono-, di-, and trisubstituted arenes well two examples biphenyls rationally explore site C(sp2)–H oxidation. isolated organometallic arene were treated NaClO2 formed desired iridium η5-phenoxo products. While site-selective observed for some compounds, most yielded mixture regioisomers. Regioselectivity primarily determined by electronic factors, while sterics influenced sites that electronically similar.

Язык: Английский

Palladium-catalyzed chemoselective N-monoallylation of aromatic amines with diallylamine through a borrowing hydrogen strategy DOI
Chengcheng Fang, Jian Zhen Ou, Xiaoye Mo

и другие.

Tetrahedron, Год журнала: 2025, Номер unknown, С. 134648 - 134648

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0
Pyridinylphenols: advances in multidisciplinary research and applications driven by multifunctional properties DOI

Zhen-Fu Lin,

Zhongyu Li, Jie Li

и другие.

Dyes and Pigments, Год журнала: 2025, Номер unknown, С. 112866 - 112866

Опубликована: Май 1, 2025

Язык: Английский

Процитировано

0
Direct Amination of Anilines Utilizing Dearomatized Phenolate Species DOI
Shaofeng Wu, Haitao Li, Shicheng Dong

и другие.

Organic Letters, Год журнала: 2025, Номер unknown

Опубликована: Май 15, 2025

Activation of the aryl C-N bond underpins critical challenges in modern organic synthesis. Herein, direct amination anilines is presented via hypervalent iodine-mediated transient dearomatized phenolate intermediates, enabling selective C(aryl)-NH2 cleavage under mild conditions. A library bioactive p-alkylaminophenols synthesized up to 85% yields within 3 h. Being used late-stage drug diversification and mechanistic studies, this protocol offers a modular platform for complex amine construction.

Язык: Английский

Процитировано

0
Strategies for Arene Dissociation from Transition Metal eta-6-Arene Complexes DOI Creative Commons
Brett D. Akana-Schneider, Yahui Guo, Bryan Parnitzke

и другие.

Dalton Transactions, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Transition metal η 6 -arene complexes have unique properties that facilitate a variety of arene substitution reactions, rendering π-activation powerful approach for functionalization.

Язык: Английский

Процитировано

1
Exploring the Site Selectivity of Arene Oxidation in [(η5-C5Me5)Ir(η6-arene)](OTf)2 Complexes DOI
Carlota Odena, Marina Pérez‐Jiménez, Ronghui Lin

и другие.

Organometallics, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 26, 2024

The oxidation selectivity of the η6-arene ligand in a series [(η5-C5Me5)Ir(η6-arene)](OTf)2 complexes to corresponding [(η5-C5Me5)Ir(η5-phenoxo)](OTf) derivatives was studied as complementary protocol metal-catalyzed borylation-oxidation. A representative compounds prepared with mono-, di-, and trisubstituted arenes well two examples biphenyls rationally explore site C(sp2)–H oxidation. isolated organometallic arene were treated NaClO2 formed desired iridium η5-phenoxo products. While site-selective observed for some compounds, most yielded mixture regioisomers. Regioselectivity primarily determined by electronic factors, while sterics influenced sites that electronically similar.

Язык: Английский

Процитировано

0