A Novel Dual-Mode Biosensing Platform Based on Au@luminol and CdSe QDs for Detection of Trace Heavy Metal Ions in PM2.5

Biosensors and Bioelectronics, Год журнала: 2025, Номер 278, С. 117366 - 117366

Опубликована: Март 10, 2025

Язык: Английский

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Overcoming Kinetic Barriers of Remote Electrochemiluminescence on Boron-Doped Diamond via Catalytic Coreactant Oxidation

Chemical Communications, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Using an Ir( iii )-based redox mediator ([Ir(sppy) 3 ] 3- ) overcomes the traditional kinetic barrier of tri- n -propylamine oxidation on BDD, enhancing ECL from Ru( ii )-labeled beads by up to 46-fold.

Язык: Английский

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Real-Time Visualization of Endogenous H₂O₂ Production in Mammalian Spheroids by Electrochemiluminescence

Chemical & Biomedical Imaging, Год журнала: 2025, Номер unknown

Опубликована: Март 10, 2025

Язык: Английский

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Single-Atom Iron Boosts Counter Electrode Electrochemiluminescence for Biosensing

Analytical Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Апрель 6, 2025

Traditional electrochemiluminescence (ECL) detection makes it difficult to realize the spatial separation of sensing and reporting sides, which inevitably causes mutual interference between target luminescent substance. By studying relationship luminol luminescence position electrode potential in a three-electrode system, this work realized sides for first time. Experimental investigations showed that only emitted ECL signals at electrodes with positive polarity, regardless whether or negative voltage was applied. Inspired by this, we introduced carbon vacancy-modified iron single-atom catalyst (VC-Fe-N-C SAC) excellent oxygen reduction reaction (ORR) activity into working electrode, can catalyze dissolved O2 produce abundant reactive species (ROS). ROS diffused surface counter oxidize high-intensity signal an ultralow trigger potential. As proof-of-concept application, sensitive biosensor constructed microcystin-LR (MC-LR) detection. This solved substance traditional system improved accuracy sensitivity. Furthermore, introduction catalysts (SAC) avoided use coreactant H2O2 tedious electrochemical oxidation process luminol, broadened application biosensors.

Язык: Английский

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Nanoconfinement Effect and Nanozyme Catalysis Enhance ILu/HOF-14 Electrochemiluminescence for Biosensing

Analytical Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Апрель 12, 2025

A low collision frequency and an insufficient number of free radicals are the main problems leading to electroluminescence (ECL) efficiency luminol its derivatives. In order solve above issues, this work used nanoconfinement combined with nanozyme catalysis significantly enhance ECL efficiency. We assembled isoluminol (ILu) into hydrogen-bonded organic framework HOF-14 prepared a novel emitter ILu/HOF-14 for first time. Surprisingly, compared ILu/H2O2 system, signal ILu/HOF-14/H2O2 was increased by 33 times. This because porous structure effectively limited movement their frequency. Therefore, reaction rate between improved achieve amplification. To further increase radicals, we introduced hybrid Zn SAC@CuO2 NPs superior peroxidase (POD)-like activity. It could catalyze coreactant H2O2 produce large amount ROS (OH• O2•-), accelerating ILu improving signal. Based on research, dual-mode biosensing imaging platform constructed detect microcystin-LR (MC-LR). nonspecific trans-cleavage activity CRISPR-Cas12a system dynamic continuity amplification capability platform, detection sensitivity broadening avenues molecular diagnostic strategies.

Язык: Английский

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Sustained Regeneration of Hydrogen Peroxide at the Water–Gas Interface of Electrogenerated Microbubbles on an Electrode Surface

Journal of the American Chemical Society, Год журнала: 2024, Номер 146(46), С. 31945 - 31949

Опубликована: Ноя. 5, 2024

Microbubbles, inside-out microdroplets, act as extraordinary microreactors to facilitate thermodynamically unfavorable reactions in bulk solutions of water. We explored the formation hydrogen peroxide (H

Язык: Английский

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