C(sp3)‐F Bond Activation by Lewis Base‐Boryl Radicals via Concerted Electron‐Fluoride Transfer DOI
Xiao‐Song Xue,

Xueying Guo,

Yu‐Chen Zhang

и другие.

Angewandte Chemie, Год журнала: 2024, Номер unknown

Опубликована: Окт. 30, 2024

Abstract Selective C−F bond activation through a radical pathway in the presence of multiple C−H bonds remains formidable challenge, owing to extraordinarily strong strength bond. By aid density functional theory calculations, we disclose an innovative concerted electron‐fluoride transfer mechanism, harnessing unique reactivity Lewis base‐boryl radicals selectively activate resilient fluoroalkanes. This enables direct abstraction fluorine atom and subsequent generation alkyl radical, thus expanding boundaries halogen reactions.

Язык: Английский

Modular assembly of amines and diborons with photocatalysis enabled halogen atom transfer of organohalides for C(sp3)–C(sp3) bond formation DOI Creative Commons

Rong‐Bin Liang,

Tingting Miao, Xiang-Rui Li

и другие.

Chemical Science, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

A new photocatalytic approach by using the assembly of DABCO A1 and B 2 Nep B1 has been established to enable cross-coupling organohalides alkenes for C(sp 3 )–C(sp ) bond formation.

Язык: Английский

Процитировано

0
Boryl Radical Mediated Hydro(gem-diboryl)alkylation of Alkenes with Sterically Hindered NHC Boranes DOI

Ruizeng Zhang,

Hao Zhang,

Pan Xu

и другие.

Organic Letters, Год журнала: 2024, Номер unknown

Опубликована: Дек. 9, 2024

NHC boryl radical mediated halogen atom transfer (XAT) is useful in organic synthesis. Yet, most of the reaction ends only with reducing to hydrogen, that is, C-X C-H. This especially dominant for electron-deficient alkyl halides, where formed electrophilic reacts rapidly boranes. Herein, by employing a sterically hindered borane as precursor (IPr·BH

Язык: Английский

Процитировано

1
C(sp3)‐F Bond Activation by Lewis Base‐Boryl Radicals via Concerted Electron‐Fluoride Transfer DOI
Xiao‐Song Xue,

Xueying Guo,

Yuchen Zhang

и другие.

Angewandte Chemie International Edition, Год журнала: 2024, Номер unknown

Опубликована: Окт. 30, 2024

Selective C-F bond activation through a radical pathway in the presence of multiple C-H bonds remains formidable challenge, owing to extraordinarily strong strength bond. By aid density functional theory calculations, we disclose an innovative concerted electron-fluoride transfer mechanism, harnessing unique reactivity Lewis base-boryl radicals selectively activate resilient fluoroalkanes. This enables direct abstraction fluorine atom and subsequent generation alkyl radical, thus expanding boundaries halogen reactions.

Язык: Английский

Процитировано

0
C(sp3)‐F Bond Activation by Lewis Base‐Boryl Radicals via Concerted Electron‐Fluoride Transfer DOI
Xiao‐Song Xue,

Xueying Guo,

Yu‐Chen Zhang

и другие.

Angewandte Chemie, Год журнала: 2024, Номер unknown

Опубликована: Окт. 30, 2024

Abstract Selective C−F bond activation through a radical pathway in the presence of multiple C−H bonds remains formidable challenge, owing to extraordinarily strong strength bond. By aid density functional theory calculations, we disclose an innovative concerted electron‐fluoride transfer mechanism, harnessing unique reactivity Lewis base‐boryl radicals selectively activate resilient fluoroalkanes. This enables direct abstraction fluorine atom and subsequent generation alkyl radical, thus expanding boundaries halogen reactions.

Язык: Английский

Процитировано

0