Cobalt-Catalyzed C–H Bond Functionalization: a Personal Account DOI
Liene Grigorjeva, Aleksandrs Cizikovs, Lukass Lukasevics

и другие.

Synlett, Год журнала: 2025, Номер unknown

Опубликована: Апрель 29, 2025

Abstract The development of green and sustainable synthetic methods is great interest worldwide. Today the direct activation functionalization relatively inert C–H bonds one top fields in organic chemistry, this strategy already represents a more environmentally friendly approach due to its atom step economy compared alternative C–C C–Het bond-forming processes. Much progress has been made developing bond using noble-metal catalysts. Cobalt recently emerged as an attractive because it less toxic, cheaper, abundant than noble metals. This Account summarizes cobalt-catalyzed bond-functionalization that have developed during corresponding author’s research career. 1 Introduction Background 2 Bond Functionalization 8-Aminoquinoline Benzamides 3 Mechanistic Investigations Cobalt-Catalyzed, Aminoquinoline-Directed 4 C(sp2)–H Phosphinamides 5 Carbonylation Sulfonamides 6 Benzoic Acids 7 Phenylglycine Derivatives 8 Phenylalanine 9 Conclusion

Язык: Английский

Cobalt-Catalyzed C–H Bond Functionalization: a Personal Account DOI
Liene Grigorjeva, Aleksandrs Cizikovs, Lukass Lukasevics

и другие.

Synlett, Год журнала: 2025, Номер unknown

Опубликована: Апрель 29, 2025

Abstract The development of green and sustainable synthetic methods is great interest worldwide. Today the direct activation functionalization relatively inert C–H bonds one top fields in organic chemistry, this strategy already represents a more environmentally friendly approach due to its atom step economy compared alternative C–C C–Het bond-forming processes. Much progress has been made developing bond using noble-metal catalysts. Cobalt recently emerged as an attractive because it less toxic, cheaper, abundant than noble metals. This Account summarizes cobalt-catalyzed bond-functionalization that have developed during corresponding author’s research career. 1 Introduction Background 2 Bond Functionalization 8-Aminoquinoline Benzamides 3 Mechanistic Investigations Cobalt-Catalyzed, Aminoquinoline-Directed 4 C(sp2)–H Phosphinamides 5 Carbonylation Sulfonamides 6 Benzoic Acids 7 Phenylglycine Derivatives 8 Phenylalanine 9 Conclusion

Язык: Английский

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