Recent Developments for the Catalytic Asymmetric Synthesis of Indolin-3-one Derivatives

Organic & Biomolecular Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

2,2-Disubstituted indolin-3-ones, which are essential components in many manufactured chemicals, dyes, and naturally occurring bioactive alkaloids, have emerged as exciting synthetic targets. Much attention has been paid to accessing these units, particularly an asymmetric fashion, during the last decade. In this review article, we discuss current state of available methods with existing mechanistic pathways for chiral indolin-3-one derivatives under various catalytic systems. This overall presentation protocols access 2,2-disubstituted or fused indolin-3-ones aza-quaternary centre is categorized based on reaction modes 2-substituted-3H-indole-3-one other similar protocols.

Язык: Английский

Organocatalyzed Asymmetric [2+2] Cycloaddition of Saccharin-Derived Endocyclic Ketimines and Allenoates for the Synthesis of Fused Azetidines

Tetrahedron Chem, Год журнала: 2025, Номер 14, С. 100133 - 100133

Опубликована: Май 10, 2025

Язык: Английский