Advances of Metal‐Based Nanomaterials in the Prevention and Treatment of Oral Infections
Advanced Healthcare Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 17, 2025
The
complicated
environment
of
the
oral
cavity
presents
significant
challenges
to
traditional
antibacterial
approaches,
which
has
driven
exploration
novel
therapeutic
strategies.
Metal-based
nanomaterials
(MNMs),
with
diverse
mechanisms
(e.g.,
membrane
disruption,
oxidative
stress)
and
evolution
from
empirical
theory-guided
design,
exhibit
immense
potential.
This
review
introduces
pioneering
Hierarchical
Response
Strategy
Framework,
systematically
classifying
MNM
systems
into
three
progressive
levels:
Primary
category,
comprising
MNMs
that
exert
spontaneous
effects
based
on
inherent
physicochemical
properties
ion
release);
Secondary
including
precisely
controlled
actions
by
microenvironmental
or
stimulus-responsive
light-induced
ROS);
Tertiary
encompassing
integrate
regenerative
functions
for
multidimensional
therapy
remineralization).
Through
this
framework,
authors
elucidate
MNMs'
transition
single-function
precision-controlled,
multifunctional
synergy,
analyze
impact
metal
elements
structural
design
efficacy,
summarize
their
applications
in
dental
caries,
endodontic
infections,
periodontal
disease,
etc.
framework
offers
a
perspective
existing
research
theoretical
foundation
rational
next-generation
precise,
smart,
comprehensive
anti-infective
materials.
Язык: Английский
Mild Phototherapy Strategies for Preventing Pathogen Infection and Enhancing Cell Proliferation in Diabetic Wound
Mingji Jiang,
Renhao Nie,
Jing Kang
и другие.
Advanced Healthcare Materials,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 27, 2025
Abstract
Excessive
inflammation,
bacterial
infection,
and
impaired
cell
proliferation
posed
significant
challenges
to
diabetic
wound
healing.
There
is
an
urgent
need
for
effective
method
that
can
simultaneously
provide
antibacterial
activity
promote
facilitate
the
healing
of
bacteria‐infected
wounds.
In
this
study,
a
novel
nanoplatform,
GDYO‐VPIM‐Au
designed,
by
co‐decorating
1‐vinyl‐3‐pentylimidazolium
bromide
([VPIM]Br)
gold
nanorods
(Au
NRs)
on
graphdiyne
oxide
(GDYO)
nanosheets.
exhibited
excellent
properties
against
drug‐resistant
bacteria
through
reactive
oxygen
species
(ROS)
generation
electrostatic
interactions.
Moreover,
with
synergistic
effect
mild
phototherapy
therapy
(mPTT)
produced
Au
NRs
efficient
significantly
accelerate
infected
This
work
represented
promising
therapeutic
strategy
addressing
infections
enhancing
Язык: Английский
Anthracene and pyrene containing fluorescent metallacycles/cages (MOCs) and their applications
APL Materials,
Год журнала:
2025,
Номер
13(5)
Опубликована: Май 1, 2025
Metal–organic
cycle/cages
(MOCs)
are
a
class
of
molecular
structures
characterized
by
their
unique
shapes
and
dimensions,
created
using
the
systematic
combination
an
organic
donor
metal
center.
Due
to
versatile
properties,
MOCs
highly
useful
in
materials
science.
Owing
structural
photoelectric
polycyclic
aromatic
hydrocarbons
have
significant
application
potential
optoelectronic
devices,
chemical
sensing,
biomedical
fields.
Fluorescent
constructed
with
units
such
as
anthracene
pyrene
backbones
show
fluorescence
properties
broad
applications
recognition,
bioimaging,
functional
materials.
This
review
highlights
latest
research
progress
on
these
multiple
areas,
including
luminescence,
resonance
energy
transfer,
host–guest
chemistry,
bioimaging.
In
addition,
design
strategies
related
involving
conformational
distortions
cycloaddition
reactions
discussed.
provides
summary
advances
this
field
during
past
three
years.
Язык: Английский