Journal of the American Chemical Society,
Год журнала:
2018,
Номер
140(13), С. 4508 - 4511
Опубликована: Март 26, 2018
Carborane
cage
chirality
is
an
outstanding
issue
of
great
interest
as
the
icosahedral
carboranes
have
wide
applications
in
medicinal
and
materials
chemistry.
The
synthesis
optically
active
carborane
derivatives,
whose
associated
with
substitution
patterns
on
polyhedron,
will
open
new
avenues
to
We
report
herein
efficient
method
achieve
chiral-at-cage
arylation
o-carboranes
high
regio-
enantioselectivities
by
a
strategy
palladium-catalyzed
asymmetric
intramolecular
B-H
cyclization.
This
represents
first
example
enantioselective
reaction
carboranes,
providing
way
for
construction
compounds
skeletons.
Journal of the American Chemical Society,
Год журнала:
2024,
Номер
146(11), С. 7791 - 7802
Опубликована: Март 10, 2024
The
development
of
new
synthetic
methods
for
B–H
bond
activation
has
been
an
important
research
area
in
boron
cluster
chemistry,
which
may
provide
opportunities
to
broaden
the
application
scope
clusters.
Herein,
we
present
a
reaction
strategy
direct
site-selective
functionalization
nido-carboranes
initiated
by
photoinduced
cage
via
noncovalent
cage···π
interaction.
As
result,
nido-carborane
radical
is
generated
through
single
electron
transfer
from
3D
2D
photocatalyst
upon
irradiation
with
green
light.
resulting
transient
could
be
directly
probed
advanced
time-resolved
EPR
technique.
In
air,
subsequent
transformations
active
have
led
efficient
and
selective
B–N,
B–S,
B–Se
couplings
presence
N-heterocycles,
imines,
thioethers,
thioamides,
selenium
ethers.
This
protocol
also
facilitates
both
late-stage
modification
drugs
synthesis
nido-carborane-based
drug
candidates
neutron
capture
therapy
(BNCT).
Inorganic Chemistry Frontiers,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
A
nickel-catalyzed
direct
cage
B–H
poly-chalcogenation
of
icosahedral
carborane
clusters,
enabled
by
a
variable
bidentate
8-aminoquinoline
traceless
directing
group,
has
been
developed
under
oxidant-free
and
weakly
basic
conditions.
Journal of the American Chemical Society,
Год журнала:
2018,
Номер
140(13), С. 4508 - 4511
Опубликована: Март 26, 2018
Carborane
cage
chirality
is
an
outstanding
issue
of
great
interest
as
the
icosahedral
carboranes
have
wide
applications
in
medicinal
and
materials
chemistry.
The
synthesis
optically
active
carborane
derivatives,
whose
associated
with
substitution
patterns
on
polyhedron,
will
open
new
avenues
to
We
report
herein
efficient
method
achieve
chiral-at-cage
arylation
o-carboranes
high
regio-
enantioselectivities
by
a
strategy
palladium-catalyzed
asymmetric
intramolecular
B-H
cyclization.
This
represents
first
example
enantioselective
reaction
carboranes,
providing
way
for
construction
compounds
skeletons.
