bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 23, 2025
A
bstract
Individual
differences
in
neural
circuits
underlying
emotional
regulation,
motivation,
and
decision-making
are
implicated
many
psychiatric
illnesses.
Interindividual
variability
these
may
manifest,
at
least
part,
as
individual
impulsivity
both
normative
clinically
significant
levels.
Impulsivity
reflects
a
tendency
towards
rapid,
unplanned
reactions
to
internal
or
external
stimuli
without
considering
potential
negative
consequences
coupled
with
difficulty
inhibiting
responses.
Here,
we
use
multivariate
brain-based
predictive
models
explore
the
bases
of
across
multiple
behavioral
scales,
neuroanatomical
features
(cortical
thickness,
surface
area,
gray
matter
volume),
sexes
(females
males)
large
sample
youth
from
Adolescent
Brain
Cognitive
Development
(ABCD)
Study
baseline
(n=9,099)
two-year
follow-up
(n=6,432).
is
significantly
associated
variability,
associations
vary
scales
features.
broadly
maps
onto
cortical
thickness
dispersed
regions
(e.g.,
inferior
frontal,
lateral
occipital,
superior
entorhinal),
well
area
volume
specific
medial
parahippocampal,
cingulate)
polar
frontal
temporal)
territories.
Importantly,
while
relationships
stable
time
points,
others
sex-specific
dynamic.
These
results
highlight
complexity
between
neuroanatomy
features,
sexes,
points
youth.
findings
suggest
that
neuroanatomy,
combination
other
biological
environmental
factors,
key
driver
As
such,
markers
help
identify
increased
risk
for
developing
impulsivity-related
Furthermore,
this
work
emphasizes
importance
adopting
multidimensional
approach
neuroimaging
research.
Heliyon,
Год журнала:
2025,
Номер
11(4), С. e42712 - e42712
Опубликована: Фев. 1, 2025
In
recent
years,
there
has
been
an
increase
in
emotional
and
behavioral
disorders
children
adolescents
that
directly
affect
their
personal,
school,
family,
social
spheres.
It
proposed
serious
games
designed
to
train
regulation
skills
can
be
a
more
effective,
accessible,
attractive
alternative
for
than
conventional
therapies.
However,
is
limited
number
of
studies
providing
evidence
the
effectiveness
these
applications.
The
aim
this
review
analyze
level
effectiveness,
feasibility
acceptability
aged
6
18
classified
universal
population
samples,
at
risk
diagnosed.
A
systematic
papers
published
between
2008
2023
was
conducted
following
PRISMA
statement
guidelines.
databases
Scopus,
Web
Science,
PubMed,
ERIC,
IEEE
Xplore,
ACM
Digital
Library
were
used.
Thirty-three
articles
identified
referred
adolescents.
All
used
report
or
self-report
measures
code
recognition
emotions
oneself
decrease
emotions.
Internal
validity
assessed
using
Cochrane
RoB
2
tool
randomized
controlled
trials
ROBINS-I
non-randomized
studies.
random
effects
model
implemented,
effect
sizes
calculated
as
Hedge's
g.
Although
are
limitations
interpreting
results,
such
lack
long-term
follow-up,
game
interventions
incorporated
biofeedback
provided
strongest
generalizability
learned
emotion
real
life.
While
does
not
always
imply
clinically
significant
change,
results
show
acceptable,
feasible
learning
strategies
reducing
symptoms
related
depression,
anxiety,
impulse
control.
bioRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 23, 2025
A
bstract
Individual
differences
in
neural
circuits
underlying
emotional
regulation,
motivation,
and
decision-making
are
implicated
many
psychiatric
illnesses.
Interindividual
variability
these
may
manifest,
at
least
part,
as
individual
impulsivity
both
normative
clinically
significant
levels.
Impulsivity
reflects
a
tendency
towards
rapid,
unplanned
reactions
to
internal
or
external
stimuli
without
considering
potential
negative
consequences
coupled
with
difficulty
inhibiting
responses.
Here,
we
use
multivariate
brain-based
predictive
models
explore
the
bases
of
across
multiple
behavioral
scales,
neuroanatomical
features
(cortical
thickness,
surface
area,
gray
matter
volume),
sexes
(females
males)
large
sample
youth
from
Adolescent
Brain
Cognitive
Development
(ABCD)
Study
baseline
(n=9,099)
two-year
follow-up
(n=6,432).
is
significantly
associated
variability,
associations
vary
scales
features.
broadly
maps
onto
cortical
thickness
dispersed
regions
(e.g.,
inferior
frontal,
lateral
occipital,
superior
entorhinal),
well
area
volume
specific
medial
parahippocampal,
cingulate)
polar
frontal
temporal)
territories.
Importantly,
while
relationships
stable
time
points,
others
sex-specific
dynamic.
These
results
highlight
complexity
between
neuroanatomy
features,
sexes,
points
youth.
findings
suggest
that
neuroanatomy,
combination
other
biological
environmental
factors,
key
driver
As
such,
markers
help
identify
increased
risk
for
developing
impulsivity-related
Furthermore,
this
work
emphasizes
importance
adopting
multidimensional
approach
neuroimaging
research.
