Soil aggregates as massively concurrent evolutionary incubators

The ISME Journal, Год журнала: 2017, Номер 11(9), С. 1943 - 1948

Опубликована: Апрель 14, 2017

Язык: Английский

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Multi-kingdom ecological drivers of microbiota assembly in preterm infants

Nature, Год журнала: 2021, Номер 591(7851), С. 633 - 638

Опубликована: Фев. 24, 2021

Язык: Английский

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Toxicity drives facilitation between 4 bacterial species

Proceedings of the National Academy of Sciences, Год журнала: 2019, Номер 116(32), С. 15979 - 15984

Опубликована: Июль 3, 2019

Competition between microbes is extremely common, with many investing in mechanisms to harm other strains and species. Yet positive interactions species have also been documented. What makes help or each currently unclear. Here, we studied the 4 bacterial capable of degrading metal working fluids (MWF), an industrial coolant lubricant, which contains growth substrates as well toxic biocides. We were surprised find only neutral Using mathematical modeling further experiments, show that this community likely due toxicity MWF, whereby species' detoxification benefited others by facilitating their survival, such they could grow degrade MWF better when together. The addition nutrients, reduction toxicity, more instead resulted competitive behavior. Our work provides support stress gradient hypothesis showing how harsh, environments can strongly favor facilitation microbial mask underlying interactions.

Язык: Английский

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Lotka-Volterra pairwise modeling fails to capture diverse pairwise microbial interactions

eLife, Год журнала: 2017, Номер 6

Опубликована: Март 28, 2017

Pairwise models are commonly used to describe many-species communities. In these models, an individual receives additive fitness effects from pairwise interactions with each species in the community ('additivity assumption'). All typically represented by a single equation where parameters reflect signs and strengths of ('universality Here, we show that fails qualitatively capture diverse microbial interactions. We build mechanistic reference for two engaging commonly-found chemical-mediated interactions, attempt derive models. Different equations appropriate depending on whether mediator is consumable or reusable, interaction mediated one more mediators, sometimes even quantitative details (e.g. relative species, initial conditions). Our results, combined potential violation additivity assumption communities, suggest modeling will often fail predict dynamics.

Язык: Английский

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Trophic Interactions and the Drivers of Microbial Community Assembly

Current Biology, Год журнала: 2020, Номер 30(19), С. R1176 - R1188

Опубликована: Окт. 1, 2020

Despite numerous surveys of gene and species content in heterotrophic microbial communities, such as those found animal guts, oceans, or soils, it is still unclear whether there are generalizable biological ecological processes that control their dynamics function. Here, we review experimental theoretical advances to argue networks trophic interactions, which the metabolic excretions one primary resource for another, constitute central drivers community assembly. Trophic interactions emerge from deconstruction complex forms organic matter into a wealth smaller intermediates, some released environment serve nutritional buffet community. The structure emergent network rate at resources supplied many features assembly, including relative contributions competition cooperation emergence alternative states. Viewing assembly through lens also has important implications spatial communities well functional redundancy taxonomic groups. Given ubiquity across environments, they impart common logic can enable development more quantitative predictive ecology.

Язык: Английский

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Drivers of microbial community structure in forest soils

Applied Microbiology and Biotechnology, Год журнала: 2018, Номер 102(10), С. 4331 - 4338

Опубликована: Март 29, 2018

Язык: Английский

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Prospects for Biological Soilborne Disease Control: Application of Indigenous Versus Synthetic Microbiomes

Phytopathology, Год журнала: 2016, Номер 107(3), С. 256 - 263

Опубликована: Ноя. 29, 2016

Biological disease control of soilborne plant diseases has traditionally employed the biopesticide approach whereby single strains or strain mixtures are introduced into production systems through inundative/inoculative release. The significant barriers that have long been recognized, including a generally limited spectrum target pathogens for any given biocontrol agent and inadequate colonization host rhizosphere, which can plague progress in utilization this resource commercial field-based crop systems. Thus, although potential exists, model continued to lag its application. New omics' tools enabled more rapid screening microbial populations allowing identification with multiple functional attributes may contribute pathogen suppression. Similarly, these technologies also enable characterization consortia natural provide framework construction synthetic microbiomes control. Harnessing microbiome indigenous agricultural soils suppression application specific management strategies goal pathologists. Although tactic possesses limitation, our enhanced understanding suppressive soil community metagenomic analysis methods opportunity devise effective schemes. As communities large part fostered by resources endemic substrate mediated recruitment disease-suppressive constitutes practical means foster their establishment

Язык: Английский

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Cooperation in microbial communities and their biotechnological applications

Environmental Microbiology, Год журнала: 2017, Номер 19(8), С. 2949 - 2963

Опубликована: Апрель 27, 2017

Summary Microbial communities are increasingly utilized in biotechnology. Efficiency and productivity many of these applications depends on the presence cooperative interactions between members community. Two key processes underlying production public goods metabolic cross‐feeding, which can be understood general framework ecological evolutionary (eco‐evo) dynamics. In this review, we illustrate relevance microbial biotechnological processes, discuss their mechanistic origins analyse resilience. Cooperative behaviours damaged by emergence ‘cheating’ cells that benefit from but do not contribute to them. Despite this, stabilized spatial segregation, feedbacks dynamics ecology community, role regulatory systems coupled environmental conditions action horizontal gene transfer. enrich with a higher degree robustness against stress facilitate evolution more complex traits. Therefore, resilience ability constraint detrimental mutants should considered design robust applications.

Язык: Английский

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Design, construction, and in vivo augmentation of a complex gut microbiome

Cell, Год журнала: 2022, Номер 185(19), С. 3617 - 3636.e19

Опубликована: Сен. 1, 2022

Язык: Английский

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Interaction networks, ecological stability, and collective antibiotic tolerance in polymicrobial infections

Proceedings of the National Academy of Sciences, Год журнала: 2017, Номер 114(40), С. 10666 - 10671

Опубликована: Сен. 18, 2017

Significance In many infections, multiple microbial species are present simultaneously. Such polymicrobial infections can be viewed as small ecosystems. Do bacteria in these communities interact with each other? If so, do interactions affect the stability of ecosystem, particular, when antibiotics present? We focus on urinary tract and demonstrate that there ample ecological between different bacterial species, both presence absence antibiotics. further show they crucially ecosystem resilience to environmental perturbations such Understanding nature point toward ways disrupting infection ecosystems, which could potentially used a new strategy eradicate infective communities.

Язык: Английский

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