Anti-obesity Medications for Monogenic Syndromic Obesity DOI

Shilpa Chugh Garcha,

Sanjay Kalra

Опубликована: Янв. 1, 2025

Язык: Английский

Impact of COVID-19 Diagnosis on Weight Trajectories of Children in the US National COVID Cohort Collaborative DOI Creative Commons
Md Mozaharul Mottalib, Thao-Ly T. Phan, Carolyn T. Bramante

и другие.

medRxiv (Cold Spring Harbor Laboratory), Год журнала: 2025, Номер unknown

Опубликована: Янв. 5, 2025

Abstract Background The COVID-19 pandemic has exacerbated the obesity epidemic, with both adults and children demonstrating rapid weight gain during pandemic. However, impact of having a diagnosis on this trend is not known. Methods Using longitudinal data from January 2019 to June 2023 collected by US National Institute for Health’s COVID Cohort Collaborative (N3C), (age 2–18 years) positive test results (n=11,474, 53% male, mean [SD] age 5.57 [±3.29] years, 54% white, 5.2 [±2.9] BMI observations per participants) were matched negative identical demographic characteristics similar observation window. We compared percentile trajectories between cohorts, further evaluation performed patients stratified hospitalization status. Results had greater increase in %BMI p95 than (average 2.34 (±7.73) 1.46 (±6.09), p<0.0005). gained more after their before. Non-hospitalized hospitalized 2.38 (±7.65)) 1.87 (±8.54)). Mixed effect regression analyses demonstrated that these associations remained even adjusting time, demographics, baseline . Conclusions Having was associated gain, especially early Future research should explore reasons association implications future health emergencies. Authors’ Contributions M.M.M. drafted initial manuscript assisted curation, formal analysis, methodology, visualization. T.T.P. study design, interpretation results, funding acquisition, drafting editing. C.T.B. C.G.C analysis results. L.A.P. R.B. supervised resources, All authors conceptualization approved it publication. Author Disclosure Statement declare no conflicts interest. Impact This investigating shows led significant among aged 6-11, boys gaining girls. COVID-19-positive found be at risk weight. Declarations described publication conducted or tools accessed through NCATS N3C Data Enclave https://covid.cd2h.org Attribution & Publication Policy v 1.2-2020-08-25b supported U24 TR002306, Axle Informatics Subcontract: NCATS-P00438-B, [DUR RP-0BDD0E] NIH awards, P20GM103446 U54-GM104941. possible because whose information included within organizations ( https://ncats.nih.gov/n3c/resources/data-contribution/data-transfer-agreement-signatories ) scientists who have contributed ongoing development community resource [ https://doi.org/10.1093/jamia/ocaa196 ]

Язык: Английский

Процитировано

0

Dietary habits and weight change during the second wave of the COVID-19 pandemic among the Egyptian population DOI Creative Commons
Samar Abd ElHafeez, Yasmine Amr Issa, Samar Tharwat

и другие.

BMC Nutrition, Год журнала: 2025, Номер 11(1)

Опубликована: Янв. 7, 2025

The pandemic of coronavirus disease–19 (COVID-19) has a profound influence on the health population. This study aimed to assess weight changes and its relation dietary habits physical activity among adult Egyptian population during second wave COVID-19 pandemic. cross–sectional was conducted using anonymous online questionnaire. questionnaire distributed across Egypt via community–based networks, social institutional emailing lists, professional organizations collect data sociodemographic, clinical history, lifestyle habits, activity, anthropometric measurements, stressing factors. participants (n = 1000) had median (interquartile range) age 34.0 (23.0–40.0) years, with 18.7% males, 96.6% having university or postgraduate education. Among them, 69.1% reported gain, 21.3% no change, 9.6% loss. Weight loss predicted by following reports daily [adjusted odds ratio (AOR) 0.50 (95% CI, 0.27–0.93), p 0.03], monthly income change [AOR 2.52 1.51–4.22), < 0.001], starting antidepressants 3.57 1.08–11.76), increase in media use 1.81 1.05–3.13), 0.03]. gain diet 1.57 1.11–2.21), 0.01], 0.49 0.35–0.69), unhealthy food intake 0.40 0.28–0.57), 0.001] More intervention programs aiming improve should be rapidly implemented reduce consequences Egyptians keep healthy weight.

Язык: Английский

Процитировано

0

Circumstances Versus Efforts: Dissecting the Drivers of Adolescent Obesity Inequality DOI Open Access
Kangkang Zhang, Jingjing Fan, Xinpeng Xu

и другие.

Journal of Paediatrics and Child Health, Год журнала: 2025, Номер unknown

Опубликована: Янв. 19, 2025

ABSTRACT Background Previous studies have focused predominantly on socioeconomic disparities in adolescent obesity, but the sources of inequality may be more extensive. Objectives We aim to quantify and decompose opportunity (IOp) obesity caused by circumstances examine indirect effects these through key effort factors. Methods Based IOp framework previous evidence, we categorised age, gender, status, family‐school environments adolescents ( N = 9117) as obesity‐related behaviours efforts. The was quantified decomposed determine contribution each circumstance. also analysed association between sleep debt calculate magnitude effects. Results Of behaviours, only showed a significant with (OR 1.21, p < 0.05). Age gender contributed 45.97% IOp, whereas status 10.43% 43.59%. Older female whose fathers held high‐status occupations tended suffer from due debt, while opposite true for mothers exercised, children, boarders, high school students, those wealthier families. Conclusions Family‐school contribute much greater than plays an essential mediating role. government bears responsibility undertake corresponding prioritised actions.

Язык: Английский

Процитировано

0

Determinants of Longitudinal Changes in Exercise Blood Pressure in a Population of Young Athletes: The Role of BMI DOI Creative Commons
Francesca Battista, Marco Vecchiato,

Kiril Chernis

и другие.

Journal of Cardiovascular Development and Disease, Год журнала: 2025, Номер 12(2), С. 74 - 74

Опубликована: Фев. 15, 2025

Higher exercise blood pressure in adults correlates with many cardiometabolic markers. The aim of this study was to investigate the main determinants longitudinal variations young athletes. A retrospective conducted on adolescent athletes who underwent at least two sport-related pre-participation screening visits, including testing a standardized incremental ramp protocol treadmill. Blood assessed rest (SBPrest), 3rd minute (SBP3min), and peak (SBPpeak). Predictors response (i.e., respective changes vs. baseline (Δ)) were determined by multivariate regression models after adjustment for age, sex, follow-up duration, related SBP values, characteristics sport, ΔBMI. total 351 (mean age 13 ± 2 years, 54% boys, average duration 3.4 2.2 years) enrolled. BMI increased 1.5 1.8 kg/m2 (p < 0.001) during follow-up. At baseline, mean SBPrest 103 14 mmHg, SBP3min 124 18 SBPpeak 154 23 mmHg. significant between-visit increase (ΔSBPrest 7.0 17.4 mmHg; p 0.001), ΔSBP3min (4.8 11 ΔSBPpeak (11.7 24 observed. significantly predicted male sex 0.01), ΔBMI number practiced sports 0.05), whereas positively gender 0.01) negatively resting heart rate 0.01). In logistic model, only independent determinant passing from lower an upper quartile while moving higher 0.001). Increase development are pressure, both light maximal intensity, population

Язык: Английский

Процитировано

0

Anti-obesity Medications for Monogenic Syndromic Obesity DOI

Shilpa Chugh Garcha,

Sanjay Kalra

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0