The Legalome: Microbiology, Omics and Criminal Justice DOI Creative Commons
Alan C. Logan, Pragya Mishra, Susan L. Prescott

и другие.

Microbial Biotechnology, Год журнала: 2025, Номер 18(3)

Опубликована: Март 1, 2025

ABSTRACT Advances in neuromicrobiology and related omics technologies have reinforced the idea that unseen microbes play critical roles human cognition behaviour. Included this research is evidence indicating gut microbes, through direct indirect pathways, can influence aggression, anger, irritability antisocial Moreover, manufacture chemicals are known to compromise cognition. For example, recent court decisions United States Europe acknowledge produce high levels of ethanol, without consumption alcohol by defendants. The dismissal driving while intoxicated charges these cases—so‐called auto‐brewery syndrome—highlights way which microbiome knowledge will enhance precision, objectivity fairness our legal systems. Here opinion essay, we introduce concept ‘legalome’—the application science forensic psychiatry criminal law. We argue rapid pace microbial discoveries, including those challenge ideas free moral responsibility, necessitate a reconsideration traditional doctrines justifications retributive punishment. implications extend beyond courtroom, challenging us reconsider how environmental factors—from diet socioeconomic conditions—might shape preventative rehabilitative efforts their effects on microbiome.

Язык: Английский

Association of Longitudinal Oral Microbiome Activity and Pediatric Concussion Recovery DOI Creative Commons

Justin Ceasar,

D. Saravanan,

Brennen A. Harding

и другие.

Microorganisms, Год журнала: 2025, Номер 13(2), С. 320 - 320

Опубликована: Фев. 1, 2025

Mild traumatic brain injury (mTBI) results in a constellation of symptoms commonly referred to as concussion. It is unclear why certain individuals experience persistent symptoms. Given the growing evidence linking microbiome with cognition and inflammation, we examined whether longitudinal patterns were associated concussion A cohort study 118 children (aged 7–21 years) was conducted. Symptoms assessed at three timepoints post-injury (4, 11, 30 days) using Post-Concussion Symptom Inventory. Saliva microbial activity measured each timepoint RNA sequencing. linear mixed model relationship between symptom burden while controlling for age, sex, days post-mTBI. The participants’ mean age 16 (±3) years. decreased across all (25 ± 22, 13 17, 5 12). elevated Lactobacillus (F = 5.47; adj. p 0.020) Saccharomyces 6.79; reduced Micrococcus 7.94, 0.015). These do not establish causative relationship, or support use measures test. Further studies are needed explore role gut–brain axis mTBI.

Язык: Английский

Процитировано

0
The Legalome: Microbiology, Omics and Criminal Justice DOI Creative Commons
Alan C. Logan, Pragya Mishra, Susan L. Prescott

и другие.

Microbial Biotechnology, Год журнала: 2025, Номер 18(3)

Опубликована: Март 1, 2025

ABSTRACT Advances in neuromicrobiology and related omics technologies have reinforced the idea that unseen microbes play critical roles human cognition behaviour. Included this research is evidence indicating gut microbes, through direct indirect pathways, can influence aggression, anger, irritability antisocial Moreover, manufacture chemicals are known to compromise cognition. For example, recent court decisions United States Europe acknowledge produce high levels of ethanol, without consumption alcohol by defendants. The dismissal driving while intoxicated charges these cases—so‐called auto‐brewery syndrome—highlights way which microbiome knowledge will enhance precision, objectivity fairness our legal systems. Here opinion essay, we introduce concept ‘legalome’—the application science forensic psychiatry criminal law. We argue rapid pace microbial discoveries, including those challenge ideas free moral responsibility, necessitate a reconsideration traditional doctrines justifications retributive punishment. implications extend beyond courtroom, challenging us reconsider how environmental factors—from diet socioeconomic conditions—might shape preventative rehabilitative efforts their effects on microbiome.

Язык: Английский

Процитировано

0