The role and therapeutic potential of mitophagy in major depressive disorder DOI Creative Commons
Xiulin Shi,

Chenyue Liu,

Li Lin

и другие.

Frontiers in Pharmacology, Год журнала: 2025, Номер 16

Опубликована: Март 26, 2025

Major depressive disorder, also known as MDD, affects more than 264 million people globally, making it a prevalent and critical health challenge. Traditional treatments show limited efficacy in many patients. Therefore, exploring new treatment methods is particularly crucial. Mitophagy, regulatory process, can help understand treat MDD. This paper focuses on the molecular mechanisms of mitophagy, starting from proteins related pathways, its role The study explores associations between mitophagy neuroinflammation, oxidative stress, neurotransmitter synthesis, neuroplasticity MDD discusses progress clinical research In addition, article describes current pharmaceutical non-pharmaceutical interventions that regulate unravels potential challenges these therapeutic strategies settings. offers deeper insight into pathogenesis scientific basis for development strategies.

Язык: Английский

The role and therapeutic potential of mitophagy in major depressive disorder DOI Creative Commons
Xiulin Shi,

Chenyue Liu,

Li Lin

и другие.

Frontiers in Pharmacology, Год журнала: 2025, Номер 16

Опубликована: Март 26, 2025

Major depressive disorder, also known as MDD, affects more than 264 million people globally, making it a prevalent and critical health challenge. Traditional treatments show limited efficacy in many patients. Therefore, exploring new treatment methods is particularly crucial. Mitophagy, regulatory process, can help understand treat MDD. This paper focuses on the molecular mechanisms of mitophagy, starting from proteins related pathways, its role The study explores associations between mitophagy neuroinflammation, oxidative stress, neurotransmitter synthesis, neuroplasticity MDD discusses progress clinical research In addition, article describes current pharmaceutical non-pharmaceutical interventions that regulate unravels potential challenges these therapeutic strategies settings. offers deeper insight into pathogenesis scientific basis for development strategies.

Язык: Английский

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