Bone-related
diseases
caused
by
fractures,
bone
infection,
cancer,
and
so
on
have
posed
a
serious
threat
to
human
health.
The
drawbacks
of
traditional
implants
are
gradually
being
solved
through
the
design
construction
nanomaterials.
Among
them,
black
phosphorus
(BP)
is
widely
adopted
in
therapy
due
its
excellent
photo-responsiveness,
biodegradability,
biocompatibility,
which
considered
as
promising
solution
strategy.
This
latest
review
intended
provide
an
elaborate
introduction
recent
advances
BP-contained
nanomaterials
for
therapy,
covers
topics
from
strategies
classified
types
osteogenic
material,
including
3D
printing
scaffolds,
hydrogels,
fibrous
materials,
others,
well
research
works
function
BP
also
discussed.
Finally,
current
status
future
prospects
BP-based
summarized
reference
further
applications.
Biomaterials Science,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
The
development
of
bioink-based
3D-printed
scaffolds
has
revolutionized
bone
tissue
engineering
(BTE)
by
enabling
patient-specific
and
biomimetic
constructs
for
regeneration.
Frontiers in Cellular and Infection Microbiology,
Год журнала:
2025,
Номер
15
Опубликована: Апрель 11, 2025
Bone
marrow
is
vital
for
hematopoiesis,
producing
blood
cells
essential
oxygen
transport,
immune
defense,
and
clotting.
However,
disorders
like
leukemia,
lymphoma,
aplastic
anemia,
myelodysplastic
syndromes
can
severely
disrupt
its
function,
leading
to
life-threatening
complications.
Traditional
treatments,
including
chemotherapy
stem
cell
transplants,
have
significantly
improved
patient
outcomes
but
are
often
associated
with
severe
side
effects
limitations,
necessitating
the
exploration
of
safer,
more
targeted
therapeutic
strategies.
Nanotechnology
has
emerged
as
a
promising
approach
addressing
these
challenges,
particularly
in
delivery
nutraceuticals—bioactive
compounds
derived
from
food
sources
potential
benefits.
Despite
their
promise,
nutraceuticals
face
clinical
limitations
due
poor
bioavailability,
instability,
inefficient
target
sites.
Nanoparticles
offer
viable
solution
by
enhancing
stability,
absorption,
transport
bone
while
minimizing
systemic
effects.
This
study
explores
range
disorders,
conventional
treatment
modalities,
nanoparticles
enhance
nutraceutical-based
therapies.
By
improving
efficacy,
could
revolutionize
disease
management,
providing
patients
effective
less
invasive
options.
These
advancements
represent
significant
step
toward
safer
efficient
approaches,
ultimately
prognosis
overall
health.
Pharmaceutics,
Год журнала:
2025,
Номер
17(4), С. 514 - 514
Опубликована: Апрель 14, 2025
Bone
infection
is
a
disease
that
seriously
affects
patients’
quality
of
life
and
physical
health.
Traditional
treatment
methods
have
many
drawbacks.
Hydrogels
loaded
with
Chinese
Medicine
(TCM),
as
an
emerging
strategy,
combine
the
advantages
good
biocompatibility
hydrogels,
adjustable
drug
release
performance,
multi-target
synergistic
TCM,
showing
great
application
potential.
This
article
elaborates
in
detail
on
research
progress
hydrogels
TCM
for
bone
infections,
including
classification
characteristics
mechanism
action
preparation
examples,
advantages,
challenges
prospects
faced.
The
aim
to
provide
new
ideas
references
clinical
infections.
Bone-related
diseases
caused
by
fractures,
bone
infection,
cancer,
and
so
on
have
posed
a
serious
threat
to
human
health.
The
drawbacks
of
traditional
implants
are
gradually
being
solved
through
the
design
construction
nanomaterials.
Among
them,
black
phosphorus
(BP)
is
widely
adopted
in
therapy
due
its
excellent
photo-responsiveness,
biodegradability,
biocompatibility,
which
considered
as
promising
solution
strategy.
This
latest
review
intended
provide
an
elaborate
introduction
recent
advances
BP-contained
nanomaterials
for
therapy,
covers
topics
from
strategies
classified
types
osteogenic
material,
including
3D
printing
scaffolds,
hydrogels,
fibrous
materials,
others,
well
research
works
function
BP
also
discussed.
Finally,
current
status
future
prospects
BP-based
summarized
reference
further
applications.